Metrics
Publication
104
Open Access
4
UN Sustainable Development Goals
Education
2000 - 2005
2000 - 2005Doctorate
Université Paris XI, Faculté De Pharmacie, France
1998 - 2005
1998 - 2005Doctorate
Hacettepe University, Sağlık Bilimleri Enstitüsü, Farmasötik Teknoloji Anabilim Dalı, Turkey
1994 - 1998
1994 - 1998Postgraduate
Hacettepe University, Sağlık Bilimleri Enstitüsü, Farmasötik Teknoloji Anabilim Dalı, Turkey
1990 - 1994
1990 - 1994Undergraduate
Hacettepe University, Eczacılık Fakültesi, Turkey
Foreign Languages
B1 Intermediate
B1 IntermediateFrench
C1 Advanced
C1 AdvancedEnglish
Research Areas
Health Sciences
Pharmacology and Therapeutics
Pharmaceutics Technology
Pharmaceutical Technology
Research Areas Based on Academic Activities
Avesis Research Areas
WoS Research Areas
Scopus Research Areas
Academic Positions
2015 - 2021
2015 - 2021Associate Professor
Erciyes University, Eczacılık Fakültesi, Eczacılık Teknolojisi
Managerial Experience
2016 - Present
2016 - PresentEthics Committee Member
Erciyes Üniversitesi, Biyoyararlanım/Biyoeşdeğerlik
2010 - Present
2010 - PresentHead of Department
Erciyes Üniversitesi, Farmasötik Teknoloji
2010 - Present
2010 - PresentErciyes University
2016 - 2019
2016 - 2019Director of the Center
Erciyes Üniversitesi, İlaç Uygulama Ve Araştırma Merkezi
2016 - 2019
2016 - 2019Erciyes University
2016 - 2016
2016 - 2016Vice Dean
Erciyes University, Eczacılık Fakültesi
2015 - 2016
2015 - 2016Erciyes University
2010 - 2015
2010 - 2015Vice Dean
Erciyes Üniversitesi, Eczacılık Fakültesi
2010 - 2015
2010 - 2015Erciyes University
Non Academic Experience
2004 - 2006
2004 - 2006Eczacı
TC Sağlık Bakanlığı İlaç ve Eczacılık Genel Müdürlüğü, Eczacı
Supervised Theses
2024
2024Doctorate
Posakonazol İçeren Kendiliğinden Nano Emülsifiye Olabilen Sistemlerin (SNEDDS) Geliştirilmesi ve Karakterizasyonu
Aktaş Y., Çelik Tekeli M. (Co-Advisor)
A.ATMAR(Student)
2020
2020Doctorate
Tip 2 diyabet tedavisinde kullanılmak üzere oral yolla uygulanacak protein/peptit içeren kendiliğinden emülsifiye olan nanoformülasyonunun geliştirilmesi, ın vitro/ın vivo değerlendirilmesi
Aktaş Y. (Co-Advisor), Çelebi F. N.
M.ÇELİK(Student)
2010
2010Postgraduate
Periodontitis Tedavisi için Tetrasiklin HCl İçeren Kitosan Boncukların Hazırlanması ve in vitro Değerlendirilmesi
AKTAŞ Y.
R.Sevinç(Student)
Articles
All (42)
SCI-E, SSCI, AHCI (30)
SCI-E, SSCI, AHCI, ESCI (33)
ESCI (3)
Scopus (32)
TRDizin (11)
Other Publications (1)
2024
20241. In vitro cellular uptake and insulin secretion studies on INS-1E cells of exendin-4-loaded self-nanoemulsifying drug delivery systems
ÇELİK TEKELİ M., Yalçın Y., Verdi H., AKTAŞ Y., Çelebi N.
Pharmaceutical Development and Technology
, vol.29, no.10, pp.1101-1110, 2024 (SCI-Expanded, Scopus)
2024
20242. An all-in-one nanoparticle for overcoming drug resistance: doxorubicin and elacridar co-loaded folate receptor targeted PLGA/MSN hybrid nanoparticles
TONBUL H., ŞAHİN A., ÖZTÜRK S. C., ULTAV G., Tavukçuoğlu E., Akbaş S., et al.
Journal of Drug Targeting
, vol.32, no.9, pp.1101-1110, 2024 (SCI-Expanded, Scopus)
2023
20233. Development and characterization of in situ gelling system containing atorvastatin-loaded polycaprolactone nanoparticles for periodontal diseases
Ünal S., Doğan O., Polat H. K., Aktaş Y.
JOURNAL OF RESEARCH IN PHARMACY , vol.27, no.5, pp.1951-1973, 2023 (TRDizin)
2023
20234. Thermosensitive Pluronic® F127-Based in situ gel formulation containing nanoparticles for the sustained delivery of paclitaxel
Ünal S., Çelik Tekeli M., Doğan O., Aktaş Y.
Medicine Science
, vol.2023, no.12, pp.224-230, 2023 (TRDizin)
2023
20235. Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors
Ünal S., Varan G., Benito J. M., Aktaş Y., Bilensoy E.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
, vol.2023, no.19, pp.139-157, 2023 (SCI-Expanded, Scopus)
2023
20236. Bisphosphonate-loaded PLGA microspheres for bone regeneration in dental surgery: formulation, characterization, stability, and comprehensive release kinetic studies
Ünal S., Aktaş Y.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
, vol.72, no.1, pp.89-100, 2023 (SCI-Expanded, Scopus)
2022
20227. Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics
Ünal S., Doğan O., Aktaş Y.
BEILSTEIN JOURNAL OF NANOTECHNOLOGY
, vol.2022, no.13, pp.1393-1407, 2022 (SCI-Expanded, Scopus)
2022
20228. PACLITAXEL-LOADED POLYCAPROLACTONE NANOPARTICLES FOR LUNG TUMORS; FORMULATION, COMPREHENSIVE IN VITRO CHARACTERIZATION AND RELEASE KINETIC STUDIES
Ünal S., Doğan O., Aktaş Y.
ANKARA UNIVERSITESI ECZACILIK FAKULTESI DERGISI
, vol.46, no.3, pp.1009-1029, 2022 (Scopus, TRDizin)
2022
20229. Tip 2 Diyabet Tedavisinde Kullanılan Exendin-4 ve Exendin-4’ün Alternatif Uygulama Yolları İçin Güncel Yaklaşımlar
ÇELİK TEKELİ M., AKTAŞ Y., ÇELEBİ F. N.
FABAD JOURNAL OF PHARMACEUTICAL SCIENCES
, vol.47, no.12, pp.266-281, 2022 (Scopus, TRDizin)
2021
202110. Therapeutic efficacy and gastrointestinal biodistribution of polycationic nanoparticles for oral camptothecin delivery in early and late-stage colorectal tumor-bearing animal model.
Ünal S., Can Öztürk S., Bilgiç E., Yanık H., Korkusuz P., Aktaş Y., et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
, vol.169, pp.168-177, 2021 (SCI-Expanded, Scopus)
2021
202111. May biodegradable and biocompatible polymeric microneedles be considered as a vaccine and drug delivery system in the covid-19 pandemic? Biyoparçalanır ve biyouyumlu polimerik mikroiğneler covid-19 pandemisinde aşı ve ilaç taşıyıcı sistem olarak değerlendirilebilir mi?
ÜNAL S., Doğan O., AKTAŞ Y.
Turkish Journal of Pharmaceutical Sciences
, vol.18, no.5, pp.527-529, 2021 (ESCI, Scopus, TRDizin)
2021
202112. Folic acid decoration of mesoporous silica nanoparticles to increase cellular uptake and cytotoxic activity of doxorubicin in human breast cancer cells
TONBUL H., Sahin A., Tavukcuoglu E., Ultav G., Akbas S., AKTAŞ Y., et al.
Journal of Drug Delivery Science and Technology
, vol.63, 2021 (SCI-Expanded, Scopus)
2021
202113. Evaluation of the hypoglycemic effect of exendin-4's new oral self-nanoemulsifying system in rats
Celik-Tekeli M., Celebi N., Tekeli M. Y., Aktas Y.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
, vol.158, 2021 (SCI-Expanded, Scopus)
2021
202114. Oral self-nanoemulsifying formulation of GLP-1 agonist peptide exendin-4: development, characterization and permeability assesment on Caco-2 cell monolayer.
Tekeli M., AKTAŞ Y., Celebi N.
Amino acids
, vol.53, pp.73-88, 2021 (SCI-Expanded, Scopus)
2020
202015. Cyclodextrin nanoparticle bound oral camptothecin for colorectal cancer: Formulation development and optimization.
Ünal S., Aktaş Y., Benito J. M., Bilensoy E.
International journal of pharmaceutics
, vol.584, pp.119468, 2020 (SCI-Expanded, Scopus)
2020
202016. Development and characterization of exendin-4 loaded self-nanoemulsifying system and in vitro evaluation on Caco-2 cell line
Aktaş Y., Çelik Tekeli M., Çelebi F. N.
Journal Of Microencapsulation , vol.37, no.1, pp.41-51, 2020 (SCI-Expanded, Scopus)
2019
201917. Development of Paclitaxel and Flurbiprofen Co-Loaded PLGA Nanoparticles: Understanding Critical Formulation and Process Parameters Using Plackett–Burman Design
ŞAHİN A., ÇABAN TOKTAŞ S., TONBUL H., YERLİKAYA F., AKTAŞ Y., ÇAPAN Y.
Istanbul Journal of Pharmacy
, vol.49, no.3, pp.161-166, 2019 (ESCI, TRDizin)
2019
201918. Novel Approach to the Treatment of Diabetes: Embryonic Stem Cell and Insulin-Loaded Liposomes and Nanocochleates
Yücel Ç., Aktaş Y., Değim Z., Yılmaz Ş., Arsoy T., Altıntaş L., et al.
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
, vol.19, pp.3706-3719, 2019 (SCI-Expanded)
2019
201919. Mechanical characterization and ex vivo evaluation of anticancer and antiviral drug printed bioadhesive film for the treatment of cervical cancer
Varan C., Şen M., Sandler N., AKTAŞ Y., BİLENSOY E., Bilensoy E.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
, vol.130, pp.114-123, 2019 (SCI-Expanded, Scopus)
2019
201920. Synthesis of Small-Sized Mesoporous Silica Nanoparticles by Experimental Design and Characterization for Further Drug Delivery
TONBUL H., Ultav G., Akbas S., Sahin A., AKTAŞ Y., ÇAPAN Y.
LATIN AMERICAN JOURNAL OF PHARMACY
, vol.38, no.11, pp.2204-2210, 2019 (SCI-Expanded, Scopus)
2018
201821. EFFECTS OF INSULIN AND EMBRYONIC STEM CELLS LOADED PLGA NANOPARTICLES ON PANCREATIC BETA TC CELLS
Yücel Ç., Aktaş Y., Değim Z., Yılmaz Ş., Arsoy T., Altıntaş L., et al.
ACTA POLONIAE PHARMACEUTICA
, vol.75, pp.1377-1389, 2018 (SCI-Expanded, Scopus)
2018
201822. Development and Characterization of Insulin-loaded Liposome-chitosan-Nanoparticle (LCS-NP) Complex and Investigation of Transport Properties Through a Pancreatic Beta Tc Cell Line
ÇELİK TEKELİ M., YÜCEL Ç., ÜNAL S., AKTAŞ Y.
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
, vol.15, no.1, pp.91-96, 2018 (ESCI, Scopus, TRDizin)
2018
201823. Nanoliposomal Resveratrol as a Novel Approach to Treatment of Diabetes Mellitus
Yücel Ç., Karatoprak G., Aktaş Y.
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
, vol.18, no.6, pp.3856-3864, 2018 (SCI-Expanded)
2017
201724. Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin inclusion complexes on bioadhesive film for cervical administration
VARAN C., WICKSTROM H., Sandler N., AKTAŞ Y., BİLENSOY E.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
, vol.531, no.2, pp.701-713, 2017 (SCI-Expanded, Scopus)
2017
201725. Dosetakselin Siklodekstrin Türevleri İle Farklı Yöntemlerle Kompleks Oluşturması Ve Oluşan İnklüzyon Komplekslerinin Karakterizasyonu
Ünal S., Yücel Ç., Tort S., Çelik Tekeli M., Aktaş Y., Bilensoy E.
Sağlık Bilimleri Dergisi , vol.26, pp.119-125, 2017 (TRDizin)
2017
201726. Physicochemical Characterization and Microbiological Evaluation of Tetracycline HCl Loaded Chitosan Beads for Periodontitis Treatment: A Preliminary Study
SEVİNÇ ÖZAKAR R., AKTAŞ Y., BİLİCİ D., AYYILDIZ A.
Journal of Allied Pharmaceutical Sciences , vol.1, no.1, pp.28-34, 2017 (Peer-Reviewed Journal)
2017
201727. Using PVA and TPGS as combined emulsifier in nanoprecipitation method improves characteristics and anticancer activity of ibuprofen loaded PLGA nanoparticles
ŞAHİN A. E., Spiroux F., Guedon I., ARSLAN F. N., Sarcan E. T., Ozkan T., et al.
PHARMAZIE
, vol.72, no.9, pp.525-528, 2017 (SCI-Expanded, Scopus)
2017
201728. Dosetakselin siklodekstrin türevleri ile farklı yöntemlerle kompleks oluşturması ve oluşan inklüzyon komplekslerinin karakterizasyonu
ÜNAL S., YÜCEL Ç., TORT S., ÇELİK TEKELİ M., AKTAŞ Y., BİLENSOY E.
Sağlık Bilimleri Dergisi , pp.119-125, 2017 (TRDizin)
2017
201729. DOSETAKSELİN SİKLODEKSTRİN TÜREVLERİ İLE FARKLI YÖNTEMLERLE KOMPLEKS OLUŞTURMASI VE OLUŞAN İNKLÜZYON KOMPLEKSLERİNİN KARAKTERİZASYONU
ÜNAL S., YÜCEL Ç., TORT S., ÇELİK TEKELİ M., AKTAŞ Y., BİLENSOY E.
Sağlık Bilimleri Dergisi , vol.26, pp.119-125, 2017 (TRDizin)
2017
201730. A small variation in average particle size of PLGA nanoparticles prepared by nanoprecipitation leads to considerable change in nanoparticles' characteristics and efficacy of intracellular delivery
Sahin A., ESENDAĞLI G., Yerlikaya F., Caban-Toktas S., Yoyen-Ermis D., Horzum U., et al.
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
, vol.45, no.8, pp.1657-1664, 2017 (SCI-Expanded, Scopus)
2017
201731. Evaluation of brain-targeted chitosan nanoparticles through blood-brain barrier cerebral microvessel endothelial cells
Sahin A., Yoyen-Ermis D., Caban-Toktas S., Horzum U., AKTAŞ Y., Couvreur P., et al.
JOURNAL OF MICROENCAPSULATION
, vol.34, no.7, pp.659-666, 2017 (SCI-Expanded, Scopus)
2016
201632. Kersetin Yüklü Kitosan Nanopartiküllerin İn Vitro Değerlendirilmesi
Yücel Ç., Şeker Karatoprak G., Aktaş Y., Koşar M.
Sağlık Bilimleri Dergisi , vol.25, no.2, pp.63-66, 2016 (TRDizin)
2015
201533. Amphiphilic cyclodextrins as enabling excipients for drug delivery and for decades of scientific collaboration: Tribute to a distinguished scientist, French representative and friend - A historical perspective
AKTAŞ Y., YENICE I., BİLENSOY E., Hıncal A. A.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
, vol.30, pp.261-265, 2015 (SCI-Expanded, Scopus)
2013
201334. Development of a New Chitosan Based Nanomaterial for Controlled Delivery of Prilocaine
Aktas Y., ATİLA A., KADIOĞLU Y.
LATIN AMERICAN JOURNAL OF PHARMACY
, vol.32, no.7, pp.1048-1052, 2013 (SCI-Expanded, Scopus)
2012
201235. Development of a HPLC Method for the Determination of Cyclosporine A From Chitosan Nanoparticles
Büyüktuncel E., Yücel Ç., Kaynak M. S., Aktaş Y.
LATIN AMERICAN JOURNAL OF PHARMACY
, vol.31, pp.1083-1088, 2012 (SCI-Expanded, Scopus)
2010
201036. LC-UV Determination of Melatonin from Chitosan Nanoparticles
Yerlikaya F., Aktas Y., Çapan Y.
CHROMATOGRAPHIA
, vol.71, pp.967-970, 2010 (SCI-Expanded, Scopus)
2009
200937. A nano-medicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection
Karataş H., AKTAŞ Y., Gürsoy Özdemir Y., Bodur E., Yemişçi M., Çaban S., et al.
JOURNAL OF NEUROSCIENCE , vol.29, no.44, pp.13761-13769, 2009 (SCI-Expanded, Scopus)
2009
200938. Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles
Pınarbaşlı O., AKTAŞ Y., DALKARA T., Andrieux K., Alonso M. J., Fernandez-Megia E., et al.
PHARMAZIE
, vol.64, no.7, pp.436-439, 2009 (SCI-Expanded, Scopus)
2009
200939. Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors
Bilensoy E., Sarısözen C., Esendağlı G., Doğan A. L., AKTAŞ Y., ŞEN M., et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
, vol.371, pp.170-176, 2009 (SCI-Expanded, Scopus)
2005
200540. Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26
Aktas Y., Yemisci M., Andrieux K., Gursoy R., Alonso M., Fernandez-Megia E., et al.
BIOCONJUGATE CHEMISTRY
, vol.16, no.6, pp.1503-1511, 2005 (SCI-Expanded, Scopus)
2005
200541. Preparation and In Vitro Evaluation of Z-DEVD-FMK Loaded Chitosan Nanoparticles
AKTAŞ Y., Andrieux K., Alonso M. J., Calvo P., Gürsoy R. N., Couvreur P., et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS , vol.298, no.2, pp.378-83, 2005 (SCI-Expanded, Scopus)
2003
200342. Influence of hydroxypropyl beta-cyclodextrin on the corneal permeation of pilocarpine
AKTAŞ Y., Ünlü N., Orhan M., İrkeç M., Hıncal A. A.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
, vol.29, no.2, pp.223-230, 2003 (SCI-Expanded, Scopus)
Papers Presented at Peer-Reviewed Scientific Conferences
2024
20241. Development of Posaconazole-Loaded Self Nanoemulsifying Formulation and Evaluation of in-vitro Antifungal Activity
Aktaş Y., Atmar A., Çelik Tekeli M., Ceylan A.
21st International Pharmaceutical Technology Symposium-IPTS 2024, Ankara, Turkey, 9 - 11 September 2024, pp.303-304, (Full Text)
2024
20242. DEVELOPMENT AND CHARACTERIZATION OF POSACONAZOLE LOADED SELF NANOEMULSIFYING FORMULATION
Atmar A., Çelik Tekeli M., Aktaş Y.
14th International Symposium on Pharmaceutical Sciences (ISOPS) , Ankara, Turkey, 25 - 28 June 2024, pp.277, (Full Text)
2019
20193. ORAL ADMINISTRATION OF EXENDIN-4 AND EXENDIN-4/CHYMOSTATIN LOADED SELF NANOEMULSIFIYING SYSTEM: EVALUATION OF HYPOGLYCEMIC EFFECTS IN NON-DIABETIC AND STZ-INDUCED DIABETIC RATS
Çelik Tekeli M., Tekeli M. Y., Aktaş Y., Çelebi F. N.
8th BBBB Conference on Pharmaceutical Sciences, İzmir, Turkey, 14 - 16 October 2019, pp.83-84, (Full Text)
2019
20194. Folic Acid Conjugated Mesoporous Silica Nanoparticles For Enhanced Therapeutic Efficacy of Doxorubicin İn Breast Cancer
Tonbul H., Ultav G., Akbaş S., Şahin A., Tavukcuoğlu E., Aktaş Y., et al.
8th BBBB Conference on Pharmaceutical Sciences, İzmir, Turkey, 14 - 16 October 2019, vol.1, no.1, pp.184-186, (Full Text)
2019
20195. The Effect Of Local Release Alendronate Applied With Bone Grafts In Maxillary Sinus Lifting In Rabbits On New Bone Formation: A Micro-CT Analysis Study
Yılmaz G., Demirbaş A. E., Ünal S., Aktaş Y., Bilge S., Kütük N., et al.
Oral and Maxillofacial Surgery Society (ACBID) 13th International Congress with EACMFS Endorsement, Antalya, Turkey, 24 - 28 April 2019, vol.1, pp.135, (Full Text)
2018
20186. IN VITRO LIPOLYSIS TEST FOR EXENDIN-4 AND EXENDIN-4/CHYMOSTATIN LOADED SELF NANOEMULSIFIYING SYSTEM
ÇELİK TEKELİ M., AKTAŞ Y., ÇELEBİ F. N.
19th International Pharmaceutical Technology Symposium-IPTS 2018, 17 - 19 September 2018, (Full Text)
2018
20187. Development of Embryonic Stem Cell and Insulin-Loaded Nanocochleates And Evaluation of Efficieny on Pancreatic Beta TC Cells
YÜCEL Ç., DEĞİM Z., AKTAŞ Y., YILMAZ Ş.
19th International Pharmaceutical Technology Symposium, Antalya, Turkey, 17 - 19 September 2018, (Full Text)
2018
20188. Development of Embryonic Stem Cell and Insulin-loaded Nanocohleates and Evaluation of Efficieny on Pancreaitc Beta TC Cells
YÜCEL Ç., DEĞİM Z., AKTAŞ Y., GÖRÜRYILMAZ Ş.
19th International Pharmaceutical Technology Symposium-IPTS 2018, 17 - 19 September 2018, (Full Text)
2018
20189. PREPERATION, CHARACTERIZATION, CYTOTOXICITY EVALUATIONS OFFOLIC ACID CONJUGATED MESOPOROUS SILICA NANOPARTICLES
TONBUL H., ultav g., akbas s., sahin a., tavukcuoglu e., AKTAŞ Y., et al.
19th InternationalPharmaceutical Technology Symposium-IPTS 2018, 17 - 19 September 2018, (Full Text)
2018
201810. DEVELOPMENT AND CHARACTERIZATION OF SELF NANOEMULSIFIYING FORMULATION FOR ORAL PEPTIDE DELIVERY
Çelik Tekeli M., Aktaş Y., Çelebi N.
12th International Symposium On Pharmaceutical Sciences, Ankara, Turkey, 26 - 29 June 2018, (Summary Text)
2018
201811. SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM OF EXENDIN-4: DEVELOPMENT, CHARACTERIZATION AND ASSESMENT OF CYTOTOXICITY ON CACO-2 CELL LINE
Çelik Tekeli M., Aktaş Y., Yücel Ç., Çelebi N.
EUFEPS ANNUAL MEETING 2018, Athens, Greece, 23 - 26 May 2018, (Summary Text)
2018
201812. DEVELOPMET AND EVALUATION OF SILICA NANOPARTICLES USING A QUALITY BY DESIGN APPROACH
Tonbul H., Akbaş S., Ultav G., Şahin A., AKTAŞ Y., Çapan Y.
EUFEPS Annual Meeting 2018-Crossing Barriers For Future Medicines, Atina, Greece, 23 - 26 May 2018, (Full Text)
2018
201813. IN VITRO EVALUATION OF PACLITAXEL LOADED MESOPOROUS SILICA NANOPARTICLES
Tonbul H., Akbaş S., Ultav G., Şahin A., AKTAŞ Y., Çapan Y.
EUFEPS Annual Meeting 2018-Crossing Barriers For Future Medicines, Atina, Greece, 23 - 26 May 2018, (Full Text)
2018
201814. MECHANICAL CHARACTERIZATION AND EX VIVO EVALUATION OF INKJET PRINTED BIOADHESIVE FILM FORMULATION OF COMPLEXED PACLITAXEL AND NANOPARTICULATE CIDOFOVIR
Varan C., Şen M., Sandler N., AKTAŞ Y., Bilensoy E.
EUFEPS Annual Meeting 2018-Crossing Barriers For Future Medicines, Atina, Greece, 23 - 26 May 2018, (Full Text)
2017
201715. Development and Characterization of Paclitaxel-Loaded PLGA Nanoparticles and Cytotoxicity Assessment By MTT Assay On A549 Cell Line
ÜNAL S., YÜCEL Ç., ÇELİK TEKELİ M., ŞEKER KARATOPRAK G., AKTAŞ Y., Bilensoy E.
2nd International Conference on Natural Products for Cancer Prevention and Therapy (NPCPT 2017), Kayseri, Turkey, 8 - 11 November 2017, vol.1, no.10, pp.1036, (Summary Text)
2017
201716. Development and Characterization of Paclitaxel-loaded PLGA Nanoparticles and Evaluation of Cytotoxicity on MCF-7 cell line by MTT Assay
ÇELİK TEKELİ M., YÜCEL Ç., ÜNAL S., ŞEKER KARATOPRAK G., AKTAŞ Y., Bilensoy E.
2nd International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 8 - 11 November 2017, vol.1, no.10, pp.1030, (Full Text)
2017
201717. Development and Characterization of Paclitaxel-loaded PLGA Nanoparticles and Evaluation of Cytotoxicity on MCF-7 cell line
ÇELİK TEKELİ M., YÜCEL Ç., ÜNAL S., ŞEKER KARATOPRAK G., AKTAŞ Y., BİLENSOY E.
2nd International Conference on Natural Products for Cancer Prevention and Therapy, 8 - 11 November 2017, vol.1, pp.1030, (Summary Text)
2017
201718. Nanoparticulate Drug Delivery in Cancer Therapy
AKTAŞ Y.
Cancer Research and Targeted Therapy, Miami, United States Of America, 26 - 28 October 2017, pp.34, (Full Text)
2017
201719. INFLUENCE OF EXPERIMENTAL PARAMETERS ON THE CHARACTERISTICS OF CATIONIC NANOPARTICLES PREPARED BY NANOPRECIPITATION AND DOUBLE EMULSION METHODS
ÜNAL S., AKTAŞ Y., Bilensoy E.
2nd International Gazi Pharma Symposium (GPSS-2017), Ankara, Turkey, 11 - 13 October 2017, pp.1, (Full Text)
2017
201720. Synthesis and characterization of silica nanoparticles: Obtaining nanoparticles smaller than 100 nm
Tonbul H., Ultav G., Akbaş S., Şahin A., Kaynak M. S., AKTAŞ Y., et al.
2nd International Gazi Pharma Symposium (GPSS-2017), Ankara, Turkey, 11 - 13 October 2017, pp.1, (Full Text)
2017
201721. Development of a Self Emulsifying Drug Delivery System by Design of Experiment (DoE) Approach
ÇELİK TEKELİ M., Karaküçük A., AKTAŞ Y., Çelebi N.
2nd International Gazi Pharma Symposium (GPSS-2017), Ankara, Turkey, 11 - 13 October 2017, pp.90, (Full Text)
2017
201722. Development of Embryonic Stem Cell and Insulin-loaded Liposomes and Evaluation of Efficieny on Pancreatic Beta TC Cells
YÜCEL Ç., Değim Z., AKTAŞ Y., Yılmaz Ş.
2. Gazi Pharma Symposium Series, Ankara, Turkey, 11 - 13 October 2017, (Full Text)
2017
201723. DEVELOPMENT OF A SELF EMULSIFIYING DRUG DELIVERY SYSTEM BY DESIGN OF EXPERIMENT (DOE) APPROACH
ÇELİK TEKELİ M., KARAKÜÇÜK A. E., AKTAŞ Y., ÇELEBİ F. N.
2nd International Gazi Symposium Series, 11 - 13 October 2017, (Summary Text)
2017
201724. Development and Characterization of Self Nanoemulsifying Systems for Oral Delivery of Peptides
ÇELİK TEKELİ M., Çelebi F. N., AKTAŞ Y.
7th BBBB International Conference on Pharmaceutical Sciences, Balatonfüred, Hungary, 5 - 07 October 2017, pp.112, (Full Text)
2017
201725. Printing and Characterization of Antiviral and Nativiral and Anticancer Drug Loaded Film Formulation by Inkjet Printer
Varan C., Şen M., Sandler N., AKTAŞ Y., Bilensoy E.
7th BBBB International Conference on Pharmaceutical Sciences, Balatonfüred, Hungary, 5 - 07 October 2017, pp.178, (Full Text)
2017
201726. Printing and Characterization of Antiviral and Anticancer Drug Loaded Film Formulation by Inkjet Printer
Varan C., ŞEN M., Sandler N., AKTAŞ Y., BİLENSOY E.
7th BBBB International Conference on Pharmaceutical Sciences, 5 - 07 October 2017, (Summary Text)
2017
201727. Nanoteknolojinin Beslenme Alanındaki Uygulamaları
AKTAŞ Y.
II. Beslenme ve Diyetetik Öğrenci Kongresi, Turkey, 23 - 26 March 2017, (Summary Text)
2017
201728. Majistral Ürünlerde Temel İşlemler/Malzemeler
AKTAŞ Y.
4. Ulusal Hastane ve Kurum Eczacıları Kongresi, Turkey, 8 - 12 March 2017, (Summary Text)
2016
201629. Comparing Intracellular Delivery of PLGA and Chitosan Nanoparticles: Lessons and Challenges
Şahin A., Yerlikaya F., Esendağlı G., AKTAŞ Y., Çapan Y.
American Association of Pharmaceutical Scientists Annual Meeting 2016, Denver, United States Of America, 13 - 17 November 2016, pp.11-12, (Full Text)
2016
201630. Resverotrol ve Yeni Geliştirilen Lipozomal Formülasyonunun MTT Yöntemi ile Pankreatik Beta TC Hücre Hattı Üzerine Sitotoksisitesinin Değerlendirilmesi
YÜCEL Ç., ŞEKER KARATOPRAK G., AKTAŞ Y.
I. Ulusal Marmara Eczacılık Kongresi, Turkey, 3 - 05 November 2016, pp.145, (Summary Text)
2016
201631. Resveratrol ve yeni geliştirilen lipozomal formülasyonunun MTT yöntemi ile pankreatik beta TC hücre hattı üzerine sitotoksisitesinin değerlendirilmesi
YÜCEL Ç., ŞEKER KARATOPRAK G., AKTAŞ Y.
Ulusal Marmara Eczacılık Kongresi (UMEK), İstanbul, Turkey, 3 - 05 November 2016, pp.145, (Full Text)
2016
201632. Intracellular Delivery and Intraperitoneal Retention of Different Sized PLGA Nanoparticles Prepared by Nanoprecipitation Method. International Pharmaceutical Technology Symposium
Şahin A., Esendağlı G., Yerlikaya F., Kozlu S., Yöyen Ermiş D., Horzum U., et al.
International Pharmaceutical Technology Symposium 2016, Antalya, Turkey, 18 - 21 September 2016, pp.141-143, (Full Text)
2016
201633. Formulation and Characterization of Liposome-Chitosan Nanoparticle Complexes (LCS-NP) Containing Insulin
ÇELİK TEKELİ M., ÜNAL S., YÜCEL Ç., AKTAŞ Y.
International Pharmaceutical Technology Symposium 2016, Antalya, Turkey, 18 - 21 September 2016, pp.198-199, (Full Text)
2016
201634. Bitkisel Kaynaklı Bazı Etkin Maddeler ile Hazırlanan İlaç Taşıyıcı Sistemler ve Yapılan Çalışmalar
YÜCEL Ç., ŞEKER KARATOPRAK G., AKTAŞ Y., KOŞAR M.
Bitkisel ilaç hammaddeleri toplantısı, Trabzon, Turkey, 31 August - 05 September 2016, pp.1, (Summary Text)
2016
201635. Bitkisel Kaynaklı Etkin Maddeler İle Hazırlanan İlaç Taşıyıcı Sistemler ve Yapılan Çalışmalar
YÜCEL Ç., ŞEKER KARATOPRAK G., AKTAŞ Y., KOŞAR M.
XXII.Bitkisel İlaç Hammaddeleri Toplantısı, Turkey, 31 August - 05 September 2016, pp.92, (Summary Text)
2016
201636. Intracellular Delivery and Intraperitoneal Retention of Different Sized PLGA Nanoparticles Prepared by Nanoprecipitation Method
ŞAHİN A., ESENDAĞLI G., Yerlikaya F., KOZLU S., YOYEN ERMİŞ D., HORZUM U., et al.
International Pharmaceutical Technology Symposium 2016, 18 - 21 September 2016, (Full Text)
2016
201637. Kristal Yapıların Farmasötik Alandaki Önemi ve Polimorfizm Gösteren Etkin Maddelerin Farmasötik Formülasyonlarda Değerlendirilmeleri
ÜNAL S., AKTAŞ Y.
3. Ulusal Hastane ve Kurum Eczacıları Kongresi, Muğla, Turkey, 23 - 27 March 2016, pp.34, (Full Text)
2015
201538. Embryonic Stem Cell and Insulin-loaded PLGA Nanoparticles and Evaluation of Efficieny on Pancreatic Beta TC Cells
YÜCEL Ç., YÜCEL Ç., AKTAŞ Y., Değim Z., Yılmaz Ş.
Gazi Pharma Symposium Series, Antalya, Turkey, 12 - 15 November 2015, pp.84, (Full Text)
2015
201539. Preparation and In Vitro Evaluation Of Ziconotide Loaded PLGA And Chitosan Nanoparticles
Şahin A., Çaban S., AKTAŞ Y., Çapan Y.
Biomed Conference-Blood Brain Barrier, Barselona, Spain, 2 - 04 November 2015, pp.11-12, (Full Text)
2015
201540. Determination of Critical Parameters of Paclitaxel and Flurbiprofen Co-Loaded PLGA Nanoparticles Prepared By Nanoprecipitation
Şahin A., Çaban S., Kzyz G., Yerlikaya F., AKTAŞ Y., Çapan Y.
American Association of Pharmaceutical Scientists Annual Meeting 2015, Orlando, United States Of America, 25 - 29 October 2015, pp.13-14, (Full Text)
2015
201541. Particle Size Optimization of Ibuprofen Loaded PLGA Nanoparticles Using Box–Behnken Design
Şahin A., Çaban S., AKTAŞ Y., Çapan Y.
American Association of Pharmaceutical Scientists Annual Meeting 2015, Orlando, United States Of America, 25 - 29 October 2015, pp.11-12, (Full Text)
2015
201542. FORMULATION AND CHARACTERIZATION OF PLGA NANOPARTICLES CONTAINING DOCETAXEL
ÇELİK TEKELİ M., TANBAY M., YÜCEL Ç., AKTAŞ Y.
INTERNATIONAL MULTIDISCIPLINARY SYMPOSIUM ON Drug Research & Development, Eskişehir, Turkey, 15 - 17 October 2015, pp.220, (Full Text)
2015
201543. Nanoparticulate Cidofovir and Paclitaxel-Cyclodextrin Complex Combination in Ink Jet Printed Adhesive Film for HPV Infection
Varan C., Sandler N., AKTAŞ Y., Bilensoy E.
4th European Conference on Cyclodextrins, Lille, France, 6 September - 09 October 2015, pp.11-12, (Full Text)
2015
201544. Preparation and characterization of Cidofovir and Paclitaxel loaded bioadhesive film for the treatment of HPV-induced cervical cancer by printing technology
Varan C., Sandler N., AKTAŞ Y., Bilensoy E.
EUFEPS Annual Meeting -System Approches for Better Medicines and Health, Cenevre, Switzerland, 15 - 17 June 2015, pp.11-12, (Full Text)
2015
201545. Arometerapik karışımların hazırlanması
AKTAŞ Y.
Tamamlayıcı ve Destekleyici Bakım Uygulamaları Kongresi, Turkey, 27 - 29 May 2015
2012
201246. Preparation and in vitro Evaluation of Cyclosporin A-Loaded Liposome Chitosan Nanoparticle Complexes, 16th International Pharmaceutical Technology Symposium
AKTAŞ Y., YÜCEL Ç., büyüktuncel e., kaynak m. s., Gül M.
International Pharmaceutical Technology Symposium 2012, Antalya, Turkey, 10 - 12 September 2012, pp.11-12, (Full Text)
2012
201247. Preparation and in Vitro Evaluation of Cyclosporin a Loaded Liposome-Chitosan Nanoparticle Complexes
AKTAŞ Y., YÜCEL Ç., BÜYÜKTUNCEL S. E., KAYNAK M. S., GÜL M.
16th International Pharmaceutical Technology Symposium, Turkey, 10 - 12 September 2012, pp.0-192, (Full Text)
2012
201248. Kitosan nanopartiküllerden siklosporin A tayini için HPLC metodu geliştirilmesi
YÜCEL Ç., büyüktuncel e., kaynak m. s., AKTAŞ Y.
Kromatografi Kongresi, Tokat, Turkey, 6 - 09 June 2012, pp.1, (Full Text)
2012
201249. Kitosan Nanopartiküllerinden Siklosporn-A Tayini için HPLC Metodu Geliştirilmesi
BÜYÜKTUNCEL S. E., YÜCEL Ç., KAYNAK M. S., AKTAŞ Y.
Kromatografi 2012 Kongresi, Tokat, Turkey, 6 - 09 June 2012, (Summary Text)
2012
201250. In vitro Evaluation of Quercetin-Loaded Chitosan Nanoparticles
YÜCEL Ç., AKTAŞ Y., KOŞAR M., ŞEKER KARATOPRAK G.
10 th International Syposium Pharmaceutical Sciences, Turkey, 1 - 04 June 2012, pp.314, (Full Text)
2011
201151. Gallic acid-Loaded Chitosan Nanoparticles: A Preliminary Sudy
YÜCEL Ç., ŞEKER KARATOPRAK G., AKTAŞ Y., KOŞAR M.
European Biotechnology Congress, İstanbul, Turkey, 28 September - 01 October 2011, vol.22, pp.127, (Summary Text)
2011
201152. The dose-dependent antioxidant activity of gallic acid-loaded nanoparticles on HepG2 cell line
YÜCEL Ç., inanır m., AYCAN M. B., AKTAŞ Y.
European Biotechnology Congress, İstanbul, Turkey, 28 September - 01 October 2011, vol.22, no.1, pp.122, (Summary Text)
2011
201153. Gallic acid-loaded chitosan nanoparticles: A preliminary study
YÜCEL Ç., ŞEKER KARATOPRAK G., AKTAŞ Y., KOŞAR M.
European Biotechnology Congress, İstanbul, Turkey, 28 September - 01 October 2011, vol.22, no.1, pp.127, (Summary Text)
Books
2016
20161. Türk Farmakopesi II Monograflar Avrupa Farmakopesi Adaptasyonu
ÖZKAN Y., SALTAN H. G., SARAÇ TARHAN S., ÖZKAN S. A., AYDIN A., SÜZEN H. S., et al.
TC SAĞLIK BAKANLIĞI, 2016
2014
20142. Bitmiş Ürünlerin Teknik Bilgi Dosyasında Bulunan Güvenlilik Değerlendirmesi
AKTAŞ Y.
in: Avrupa’da Kozmetiklerin Güvenlilik Değerlendirmesi, Kadıoğlu Y., Editor, Cosming.Com, Ankara, pp.147-166, 2014
2007
20073. Development and Validation of an Analytical Method for The Determination of PBN from Chitosan Nanoparticles
Pınarbaşlı O., AKTAŞ Y., Çapan Y.
in: Advances in Chitin Science, Senel S., Varum K.M., Sumnu M.M., Hincal A.A. , Editor, Alp Ofset, Ankara, pp.370-375, 2007
2007
20074. Bioadhesive Chitosan Nanoparticles for Effective Delivery of Mitomycin C in Superficial Bladder Cancer Therapy
Sarısözen C., Doğan A. L., Esendağlı G., AKTAŞ Y., Mungan A. N., Bilensoy E.
in: Advances in Chitin Science, Senel S., Varum K.M., Sumnu M.M., Hincal A.A., Editor, Alp Ofset, Ankara, pp.236-241, 2007
2007
20075. Bioadhesive Chitosan Nanoparticles For Effectıve Delivery of Mitomycin C in Superficial Bladder Cancer Therapy
sarısözen c., DOĞAN A. L., ESENDAĞLI G., AKTAŞ Y., MUNGAN N. A., BİLENSOY E.
in: Advances in Chitin Science, , Editor, Alp Ofset, Ankara, pp.236-241, 2007
2007
20076. Development and Validation of Analytical Method For The Determination of PBN From Chitosan Nanoparticles
PINARBAŞLI O., AKTAŞ Y., ÇAPAN Y.
in: Advances in Chitin Science, , Editor, Alp Ofset, Ankara, pp.370-375, 2007
Funded Projects
2021 - 2024
2021 - 2024Posakonazol İçeren Kendiliğinden Nano Emülsifiye Olabilen Sistemlerin (SNEDDS) Geliştirilmesi ve Karakterizasyonu
Project Supported by Higher Education Institutions , BAP PhD
AKTAŞ Y. (Executive), ATMAR A.
2019 - 2021
2019 - 2021
Kolorektal Kanserlerin Lokal Tedavisinde Oral Uygulanabilen Nanopartiküler İlaç Taşıyıcı Sistem Geliştirilmesi ve in vitro/in vivo Değerlendirilmesi
Project Supported by Higher Education Institutions , BAP Research Project
AKTAŞ Y. (Executive), ÖZTÜRK S. C., BİLENSOY E., ESENDAĞLI G., KORKUSUZ P., ÜNAL S.
2017 - 2018
2017 - 2018Oral yoldan uygulanmak üzere peptid içeren nanoemülsiyon formülasyonunun geliştirilmesi ve intestinal geçiş çalışmaları
Project Supported by Higher Education Institutions , BAP Research Project
AKTAŞ Y. (Executive), ÇELEBİ N., ÇELİK TEKELİ M., YÜCEL Ç.
2016 - 2017
2016 - 2017Doğal Kaynaklı ve Sentetik İlaçların Farmasötik Formülasyon, Biyoanalitik, Toksisite ve Kalite Kontrol Araştırmaları için Ar-Ge Çalışmaları
Project Supported by Higher Education Institutions , BAP Guided
BOŞGELMEZ İ. İ. (Executive), KOŞAR M., GÜZEL Y., AYCAN M. B., AKTAŞ Y., EKEN A., et al.
2015 - 2016
2015 - 2016Resveratrol yüklü lipozomal formülasyonların geliştirilmesi ve antidiyabetik etkinliğinin araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
YÜCEL Ç. (Executive), AKTAŞ Y., ŞEKER KARATOPRAK G.
2011 - 2014
2011 - 2014''Oküler uygulama için siklosporin A yüklü lipozom-kitosan nanopartikül kompleksinin hazırlanması ve in vitro değerlendirilmesi''
Project Supported by Higher Education Institutions , BAP Research Project
AKTAŞ Y. (Executive), YÜCEL Ç., KAYNAK M. S.
Peer Reviews in Scientific Publications
January 2013
January 2013Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi
National Scientific Refreed Journal
January 2013
January 2013Drug Delivery
SCI Journal
January 2013
January 2013International Journal of Pharmaceutics
SCI Journal
January 2013
January 2013FABAD Journal of Pharmaceutical Sciences
National Scientific Refreed Journal
January 2013
January 2013Pharmaceutical Development and Technology
SCI Journal
Citations
Total Citations (WOS): 590
h-index (WOS): 10
Scientific Research / Working Group Memberships
2015 - Present
2015 - PresentTürkiye İlaç ve Tıbbi Cihaz Kurumu Bilimsel Danışma Komisyonu (Teknolojik Değerlendirme Komisyonu
-
TC Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu, Turkey
2010 - Present
2010 - Present