Doç. Dr. SEDAT ÜNAL

Yayın Ağı

Makaleler 27

1. Thermosensitive in situ gel containing alpha-lipoic acid and rutin for the treatment of corneal neovascularization: formulation, characterization, and in vivo evaluation

Polat H. K., KARAKUYU N. F., ÜNAL S., Turanli Y., PEZİK E., Sofu G. U., et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY , cilt.114, 2025 (SCI-Expanded, Scopus)

2. Herbal drug delivery for ocular treatments-an updated review

Polat H. K., Tuncel E., GÖZCÜ S., Turanli Y., KARAKUYU N. F., ÜNAL S.

EXPERIMENTAL EYE RESEARCH , cilt.260, 2025 (SCI-Expanded, Scopus)

3. Development of lacosamide-loaded in-situ gels through experimental design for evaluation of ocular irritation in vitro and in vivo

Çoban Ö., Pınar S. G., Polat H. K., GEDİK G., KARAKUYU N. F., PEZİK E., et al.

Journal of Pharmaceutical Sciences , cilt.114, sa.2, ss.1342-1350, 2025 (SCI-Expanded, Scopus)

4. **Formulation of hesperidin-loaded in situ gel for ocular drug delivery: a comprehensive study**

Gözcü S., Polat H., Gültekin Y., ÜNAL S., KARAKUYU N. F., KÖNGÜL ŞAFAK E., et al.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE , cilt.104, sa.10, ss.5846-5859, 2024 (SCI-Expanded, Scopus)

5. Flurbiprofen-encapsulated microsphere laden into heat-triggered situ gel for ocular delivery

Polat H., ÜNAL S.

ISTANBUL JOURNAL OF PHARMACY , cilt.54, sa.2, ss.108-121, 2024 (ESCI, TRDizin)

6. Gingerol containing polymeric nanofibers: a healing touch for accelerated wound recovery

Polat H., Gözcü S., ÜNAL S., Paçaci T., Aytekin E., KARAKUYU N. F., et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY , cilt.50, sa.7, ss.706-719, 2024 (SCI-Expanded, Scopus)

7. Harnessing silk fibroin microparticles for metformin delivery: A novel approach to treating corneal neovascularization

Polat H. K., Aytekin E., Karakuyu N. F., Çaylı Y. A., Çalamak S., Demirci N., et al.

Journal of Drug Delivery Science and Technology , cilt.96, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

8. Formulation Development of Lornoxicam Loaded Heat Triggered Ocular In-situ Gel Using Factorial Design

Polat H. K., Ünal S., Aytekin E., Karakuyu N. F., Pezik E., Haydar M. K., et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY , cilt.49, sa.9, ss.601-615, 2023 (SCI-Expanded, Scopus)

9. Development and characterization of in situ gelling system containing atorvastatin-loaded polycaprolactone nanoparticles for periodontal diseases

Ünal S., Doğan O., Polat H. K., Aktaş Y.

JOURNAL OF RESEARCH IN PHARMACY , cilt.27, sa.5, ss.1951-1973, 2023 (TRDizin)

10. Formulation Development of Dual Drug-Loaded Thermosensitive Ocular In Situ Gel Using Factorial Design

Polat H. K., Arslan A., ÜNAL S., HAYDAR M. K., AYTEKİN E., GÖZCÜ S., et al.

Journal of Pharmaceutical Innovation , cilt.18, sa.2, ss.768-788, 2023 (SCI-Expanded, Scopus)

11. Thermosensitive Pluronic® F127-Based in situ gel formulation containing nanoparticles for the sustained delivery of paclitaxel

Ünal S., Çelik Tekeli M., Doğan O., Aktaş Y.

Medicine Science , cilt.2023, sa.12, ss.224-230, 2023 (TRDizin) Sürdürülebilir Kalkınma

12. Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors

Ünal S., Varan G., Benito J. M., Aktaş Y., Bilensoy E.

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY , cilt.2023, sa.19, ss.139-157, 2023 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

13. Development of in situ gel containing CUR:HP-β-CD inclusion complex prepared for ocular diseases: Formulation, characterization, anti-inflammatory, anti-oxidant evaluation and comprehensive release kinetic studies

Ünal S., Polat H. K., Yuvalı D., Köngül Şafak E.

JOURNAL OF RESEARCH IN PHARMACY , cilt.27, sa.1, ss.97-119, 2023 (ESCI, Scopus, TRDizin)

14. Development of in situ gel containing CUR:HP-?-CD inclusion complex prepared for ocular diseases: Formulation, characterization, anti-inflammatory, anti- oxidant evaluation and comprehensive release kinetic studies

ÜNAL S., Polat H. K., YUVALI D., KÖNGÜL ŞAFAK E.

JOURNAL OF RESEARCH IN PHARMACY , cilt.27, sa.1, ss.97-119, 2023 (ESCI, Scopus, TRDizin)

15. Bisphosphonate-loaded PLGA microspheres for bone regeneration in dental surgery: formulation, characterization, stability, and comprehensive release kinetic studies

Ünal S., Aktaş Y.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS , cilt.72, sa.1, ss.89-100, 2023 (SCI-Expanded, Scopus)

16. **Development and characterization of in situ gelling system containing atorvastatin-loaded polycaprolactone nanoparticles for periodontal diseases**

ÜNAL S., An O. D., Polat H. K., AKTAŞ Y.

JOURNAL OF RESEARCH IN PHARMACY , cilt.27, sa.5, ss.1951-1973, 2023 (ESCI, Scopus, TRDizin)

17. Development of Besifloxacin HCL Loaded Ocular İn Situ Gels; In Vitro Characterization Study

Polat H. K., Ünal S.

Journal of Faculty of Pharmacy of Ankara University , cilt.47, sa.1, ss.39-50, 2023 (Scopus, TRDizin)

18. **Formulation development of Lornoxicam loaded heat triggered ocular in-situ gel using factorial design**

Polat H. K., ÜNAL S., AYTEKİN E., KARAKUYU N. F., PEZİK E., HAYDAR M. K., et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY , cilt.49, ss.601-615, 2023 (SCI-Expanded, Scopus)

19. Ocular Drug Delivery Systems: Traditional Review

Polat H. K., Ünal S., Aytekin E., Gözcü S.

Literatür Eczacılık Bilimleri Dergisi , cilt.11, sa.3, ss.189-200, 2022 (TRDizin)

20. Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics

Ünal S., Doğan O., Aktaş Y.

BEILSTEIN JOURNAL OF NANOTECHNOLOGY , cilt.2022, sa.13, ss.1393-1407, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

21. Development of in situ gel formulation containing bisphosphonate-loaded PLGA microspheres for bone regeneration in maxillofacial surgery applications; Formulation, in vitro characterization and release kinetic studies

Polat H. K., Ünal S.

Journal of Faculty of Pharmacy of Ankara University , cilt.46, sa.3, ss.993-1008, 2022 (Scopus)

22. PACLITAXEL-LOADED POLYCAPROLACTONE NANOPARTICLES FOR LUNG TUMORS; FORMULATION, COMPREHENSIVE IN VITRO CHARACTERIZATION AND RELEASE KINETIC STUDIES

Ünal S., Doğan O., Aktaş Y.

ANKARA UNIVERSITESI ECZACILIK FAKULTESI DERGISI , cilt.46, sa.3, ss.1009-1029, 2022 (Scopus, TRDizin) Sürdürülebilir Kalkınma

23. Therapeutic efficacy and gastrointestinal biodistribution of polycationic nanoparticles for oral camptothecin delivery in early and late-stage colorectal tumor-bearing animal model.

Ünal S., Can Öztürk S., Bilgiç E., Yanık H., Korkusuz P., Aktaş Y., et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V , cilt.169, ss.168-177, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

24. May biodegradable and biocompatible polymeric microneedles be considered as a vaccine and drug delivery system in the covid-19 pandemic? Biyoparçalanır ve biyouyumlu polimerik mikroiğneler covid-19 pandemisinde aşı ve ilaç taşıyıcı sistem olarak değerlendirilebilir mi?

ÜNAL S., Doğan O., AKTAŞ Y.

Turkish Journal of Pharmaceutical Sciences , cilt.18, sa.5, ss.527-529, 2021 (ESCI, Scopus, TRDizin) Sürdürülebilir Kalkınma

25. Cyclodextrin nanoparticle bound oral camptothecin for colorectal cancer: Formulation development and optimization.

Ünal S., Aktaş Y., Benito J. M., Bilensoy E.

International journal of pharmaceutics , cilt.584, ss.119468, 2020 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

26. Development and Characterization of Insulin-loaded Liposome-chitosan-Nanoparticle (LCS-NP) Complex and Investigation of Transport Properties Through a Pancreatic Beta Tc Cell Line

ÇELİK TEKELİ M., YÜCEL Ç., ÜNAL S., AKTAŞ Y.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES , cilt.15, sa.1, ss.91-96, 2018 (ESCI, Scopus, TRDizin) Sürdürülebilir Kalkınma

27. Dosetakselin Siklodekstrin Türevleri İle Farklı Yöntemlerle Kompleks Oluşturması Ve Oluşan İnklüzyon Komplekslerinin Karakterizasyonu

Ünal S., Yücel Ç., Tort S., Çelik Tekeli M., Aktaş Y., Bilensoy E.

Sağlık Bilimleri Dergisi , cilt.26, ss.119-125, 2017 (TRDizin)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 12

1. Determination of Phase-Solubility Diagram of Rapamycin-Cyclodextrin Inclusion Complexes

Ünal S., Doğan O., Aydın E. S.

3th International Aegean Health Areas Symposium 2023, Uşak, Türkiye, 7 - 08 Mart 2023, ss.205-211, (Tam Metin Bildiri)

2. DEVELOPMENT AND CHARACTERIZATION OF FLURBIPROFEN-LOADED PLGA MICROSPHERES FOR OCULAR DRUG ADMINISTRATION

Ünal S.

VII. International Scientific and Vocational Studies Congress – Science and Engineering, Ankara, Türkiye, 16 - 18 Aralık 2022, ss.12, (Tam Metin Bildiri)

3. DEVELOPMENT AND CHARACTERIZATION OF INDOMETHACIN LOADED pH-DEPENDENT IN SITU GELLING SYSTEM FOR SUSTAINED DRUG DELIVERY

Polat H. K., Ünal S.

6th INTERNATIONAL AEGEAN CONFERENCES, İzmir, Türkiye, 20 - 22 Aralık 2022, ss.25-39, (Tam Metin Bildiri)

4. Analysis of Drug Release Kinetics From Plga Microspheres: Mathematical Kinetic Modelling of In Vitro Release Profile

Ünal S.

11th International Medicine and Health Sciences Researches Congress, Ankara, Türkiye, 24 - 25 Aralık 2022, ss.55-60, (Tam Metin Bildiri)

5. Development of in situ Gel Formulation Containing Lactic Acid Bacteria for the Treatment of Infections in Burn Wound

Doğan O., Ünal S.

10th International Academic Studies Conference, Manisa, Türkiye, 28 - 30 Kasım 2022, ss.176, (Tam Metin Bildiri)

6. The Effect Of Local Release Alendronate Applied With Bone Grafts In Maxillary Sinus Lifting In Rabbits On New Bone Formation: A Micro-CT Analysis Study

Yılmaz G., Demirbaş A. E., Ünal S., Aktaş Y., Bilge S., Kütük N., et al.

Oral and Maxillofacial Surgery Society (ACBID) 13th International Congress with EACMFS Endorsement, Antalya, Türkiye, 24 - 28 Nisan 2019, cilt.1, ss.135, (Tam Metin Bildiri)

7. Development and Characterization of Paclitaxel-loaded PLGA Nanoparticles and Evaluation of Cytotoxicity on MCF-7 cell line by MTT Assay

ÇELİK TEKELİ M., YÜCEL Ç., ÜNAL S., ŞEKER KARATOPRAK G., AKTAŞ Y., Bilensoy E.

2nd International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Türkiye, 8 - 11 Kasım 2017, cilt.1, sa.10, ss.1030, (Tam Metin Bildiri)

8. Development and Characterization of Paclitaxel-Loaded PLGA Nanoparticles and Cytotoxicity Assessment By MTT Assay On A549 Cell Line

ÜNAL S., YÜCEL Ç., ÇELİK TEKELİ M., ŞEKER KARATOPRAK G., AKTAŞ Y., Bilensoy E.

2nd International Conference on Natural Products for Cancer Prevention and Therapy (NPCPT 2017), Kayseri, Türkiye, 8 - 11 Kasım 2017, cilt.1, sa.10, ss.1036, (Özet Bildiri)