Assoc. Prof. NAZMİYE BİTGEN

Publication Network

Articles 32

1. Enhancing docetaxel efficacy in prostate cancer: the synergistic role of thymus vulgaris extract in inducing apoptosis and autophagy

BİTGEN N., ÖNDER G. Ö., BARAN M., Karakus F. E., ÇARKIT S., YAY A. H.

Toxicology Research , vol.15, no.1, 2026 (SCI-Expanded, Scopus)

2. Synthesis, biological evaluation, molecular modeling, and DFT calculations of novel quinoline-conjugated sulfonyl hydrazones as potential anticancer agents

Özcan E., Han M. İ., Baran M., Bitgen N., Çetinkaya Y., Gündüz M. G., et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , vol.792, 2025 (SCI-Expanded, Scopus)

3. A Newly Synthesized Benzimidazolium Salt: 1-(2-Cyanobenzyl)-3-(4-Vinylbenzyl)-1H-Benzo[D]imidazol-3-ium Chloride as a Potential Anticancer Agent for Colon Cancer Treatment, In Vitro Study

BİTGEN N., Çakır M., AKKOÇ S., ALTUNTAŞ H.

Journal of Biochemical and Molecular Toxicology , vol.39, no.1, 2025 (SCI-Expanded, Scopus) Sustainable Development

4. The effects of iodine 131 treatment on chromosomal and oxidative DNA damage in papillary thyroid carcinoma

Bitgen N., Bayram F., Hamurcu Z., Başkol G., Öztürk F., Abdülrezzak Ü., et al.

Mutation Research - Genetic Toxicology and Environmental Mutagenesis , vol.898, 2024 (SCI-Expanded, Scopus) Sustainable Development

5. Enhanced kidney damage induced by increasing nonylphenol doses: impact on autophagy-related proteins and proinflammatory cytokines in rats

Yalçın B., Önder G. Ö., Göktepe Ö., Alişan Suna P., Cengiz Mat Ö., Köseoğlu E., et al.

TOXICOLOGY MECHANISMS AND METHODS , vol.15, pp.1-10, 2024 (SCI-Expanded, Scopus)

6. The Role of Folic Acid on PC3 Prostate Cancer Cell Line

Aydin F., Bitgen N., Önder G. Ö., Baran M.

Medical records-international medical journal (Online) , vol.6, no.2, pp.196-200, 2024 (TRDizin) Sustainable Development

7. **Cell proliferation, apoptosis and inflammation response of Melissa officinalis and Thymus vulgaris in SW480 colon cancer cells**

Baran M., Bitgen N., Önder G. Ö., Gürbüz P., Yay A. H.

SOUTH AFRICAN JOURNAL OF BOTANY , vol.162, pp.282-295, 2023 (SCI-Expanded, Scopus)

8. Cytotoxicity screening of Thymus vulgaris L. in breast cancer: in vitro study

Bıtgen N., Onder G. Ö., Baran M., Yay A. H.

TOXICOLOGY RESEARCH , vol.12, no.4, pp.584-590, 2023 (SCI-Expanded, Scopus)

9. Semicarbazides Carrying Indole Core: Synthesis, Cytotoxicity Evaluation against Human Breast Cancer Cell Lines, and Molecular Modeling Studies

Çelik B., Buran Uğur S., Baran M., Gündüz M. G., Keskin S., Önder G. Ö., et al.

Chemistry and Biodiversity , vol.20, no.8, 2023 (SCI-Expanded, Scopus) Sustainable Development

10. The effect of different doses of nonylphenol on the blood-testicular barrier integrity, hormone level, and DNA damage in the testes of rats

Goktepe Ö., Onder G. Ö., Cetindag E., Bitgen N., Cengiz Mat Ö., Alisan Suna P., et al.

FOOD AND CHEMICAL TOXICOLOGY , vol.177, 2023 (SCI-Expanded, Scopus)

11. Therapeutic potential of hesperidin: Apoptosis induction in breast cancer cell lines

Önder G. Ö., Göktepe Ö., Baran M., Bitgen N., Aydin F., Yay A. H.

FOOD AND CHEMICAL TOXICOLOGY , vol.176, 2023 (SCI-Expanded, Scopus)

12. Evaluation of the genotoxic effect of nonylphenol applied in different doses on the bone marrow

BİTGEN N., GÖKTEPE Ö., BARAN M., ipek E. k., YAY A. H.

International Journal of Chemistry and Technology (IJCT) , vol.7, 2023 (TRDizin)

13. Could the local anesthetics levobupivacaine and ropivacaine be used to treat colon cancer?

Bitgen N., Önder G. Ö., Öz Gergin Ö., Baran M., Goekahmetoglu G., Yay A. H.

CUKUROVA MEDICAL JOURNAL , vol.48, no.1, pp.161-167, 2023 (ESCI, TRDizin)

14. Caffeine Increased Antitumor Effects of Paclitaxel (PTX) in MCF-7 and MDA-MB-231 Breast Cancer Cells

Aydın F., ÖNDER G. Ö., GÖKTEPE Ö., BİTGEN N.

Journal of Research in Pharmacy , vol.27, no.6, pp.2242-2249, 2023 (ESCI, Scopus, TRDizin)

15. Evaluation of Genotoxic and Cytotoxic Activity of Ganoderma Lucidum In Rat Bone Marrow Induced By Lipopolysaccharide

BARAN M., BİTGEN N., KALKAN K. T., GÖKTEPE Ö., VAROL S., YAY A. H.

Dicle Tıp Dergisi , vol.49, no.1, pp.36-44, 2022 (TRDizin)

16. The Effect of Cyclosporine A on Proteins Controlling Intracellular Calcium Concentration in Breast Cancer Cells

CANER A., ÖNAL M. G., BİTGEN N., SEZER G.

JOURNAL OF MEMBRANE BIOLOGY , vol.255, no.1, pp.33-39, 2022 (SCI-Expanded, Scopus) Sustainable Development

17. Effect of Melissa officinalis L. on human breast cancer cell line via apoptosis and autophagy

Bitgen N., Baran M., Önder G. Ö., Suna P. A., Gürbüz P., Yay A. H.

CUKUROVA MEDICAL JOURNAL , vol.47, no.2, pp.765-775, 2022 (ESCI, TRDizin)

18. Chromosomal and oxidative DNA damage in non-functioning pituitary adenomas

Bitgen N., Bayram F., Hamurcu Z., Ozturk F., Simsek Y., Baskol G., et al.

ENDOKRYNOLOGIA POLSKA , no.2, pp.97-103, 2021 (SCI-Expanded, Scopus) Sustainable Development

19. Unexpected Relationship of Extracellular ATP with Intracellular Ca Concentration in HepG2 Cells

CANER A., BİTGEN N., ÖNAL M. G.

INTERNATIONAL JOURNAL OF MEDICAL RESEARCH & HEALTH SCIENCES , vol.8, no.4, pp.93-100, 2019 (ESCI)

20. What Happens to Erythrocytes When Ca2 Accumulates inThe Outside and Inside of The Cell?

CANER A., BİTGEN N., ÖNAL M. G.

International Journal of Scientific and Technological Research , 2018 (Peer-Reviewed Journal)

21. Evaluation of chromosomal DNA damage, cytotoxicity, cytostasis, oxidative DNA damage and their relationship with endocrine hormones in patients with acute organophosphate poisoning

Gündoğan K., Donmez-Altuntas H., Hamurcu Z., Akbudak I. H., Sungur M., Bitgen N., et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS , vol.825, pp.1-7, 2018 (SCI-Expanded, Scopus)

22. Increased Chromosomal and Oxidative DNA Damage in Patients with Multinodular Goiter and Their Association with Cancer

DONMEZ-ALTUNTAS H., BAYRAM F., Bitgen N., Ata S., HAMURCU Z., BAŞKOL G.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY , 2017 (SCI-Expanded, Scopus)

23. Increased micronucleus, nucleoplasmic bridge, nuclear bud frequency and oxidative DNA damage associated with prolactin levels and pituitary adenoma diameters in patients with prolactinoma

Bitgen N., Donmez-Altuntas H., BAYRAM F., CAKIR I., HAMURCU Z., DIRI H., et al.

BIOTECHNIC & HISTOCHEMISTRY , vol.91, no.2, pp.128-136, 2016 (SCI-Expanded, Scopus) Sustainable Development

24. Evaluation of chromosomal damage, cytostasis, cytotoxicity, oxidative DNA damage and their association with body-mass index in obese subjects

Donmez-Altuntas H., Sahin F., Bayram F., Bitgen N., Mert M., Guclu K., et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS , vol.771, pp.30-36, 2014 (SCI-Expanded, Scopus) Sustainable Development

25. Increased genome instability and oxidative DNA damage and their association with IGF-1 levels in patients with active acromegaly

BAYRAM F., Bitgen N., Donmez-Altuntas H., Cakir I., HAMURCU Z., Sahin F., et al.

GROWTH HORMONE & IGF RESEARCH , vol.24, no.1, pp.29-34, 2014 (SCI-Expanded, Scopus)

26. Investigation of genome instability in patients with non-alcoholic steatohepatitis

Karaman H., Karaman A., DONMEZ-ALTUNTAS H., Bitgen N., HAMURCU Z., OGUZ A., et al.

WORLD JOURNAL OF GASTROENTEROLOGY , vol.19, no.32, pp.5295-5301, 2013 (SCI-Expanded, Scopus)

27. Evaluation of genotoxicity, cytotoxicity and cytostasis in human lymphocytes exposed to patulin by using the cytokinesis-block micronucleus cytome (CBMN cyt) assay

Donmez-Altuntas H., Gokalp-Yıldız P., Bitgen N., Hamurcu Z.

MYCOTOXIN RESEARCH , vol.29, pp.63-70, 2013 (SCI-Expanded, Scopus)

28. Evaluation of the genotoxicity and cytotoxicity in the general population in Turkey by use of the cytokinesis-block micronucleus cytome assay

Donmez-Altuntas H., Bitgen N.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS , vol.748, pp.1-7, 2012 (SCI-Expanded, Scopus) Sustainable Development

29. Comparative studies of the AgNORS motifs in phytohemagglutinin-stimulated human T-lymphocytes with T-lymphocyte subgroups Fitohemaglütinin ile uyari{dotless}lmi{dotless}ş İnsan T-lenfositlerindeki AgNOR motiflerinin T-lenfosit alt gruplari{dotless} ile karşi{dotless}laşti{dotless}rmali{dotless} olarak İncelenmesi

Bitgen N., Dönmez-Altuntaş H., HAMURCU Z., Demirtaş H., Öztürk F.

Erciyes Tip Dergisi , vol.34, no.3, pp.132-136, 2012 (Scopus, TRDizin)

30. Fitohemaglütinin ile uyarılmış insan T-lenfositlerindeki agnor motiflerinin T-lenfosit alt grupları ile karşılaştırmalı olarak incelenmesi

Bitgen N., ALTUNTAŞ H. D., Hamurcu Z., DEMİRTAŞ H., ÖZTÜRK F.

Erciyes Tıp Dergisi , vol.34, no.3, pp.132-136, 2012 (Scopus, TRDizin)

31. Investigation of Genome Instability in Exfoliated Colonic Epithelial Cells and in Mitogen-Stimulated Lymphocytes of Patients with Ulcerative Colitis

Karaman A., HAMURCU Z., Donmez H., Bitken N., Karaman H., BAŞKOL M., et al.

DIGESTION , vol.85, no.3, pp.228-235, 2012 (SCI-Expanded, Scopus)

32. Micronucleus evaluation in mitogen-stimulated lymphocytes of patients with acromegaly

HAMURCU Z., Cakir I., Donmez-Altuntas H., Bitgen N., Karaca Z., Elbuken G., et al.

METABOLISM-CLINICAL AND EXPERIMENTAL , vol.60, no.11, pp.1620-1626, 2011 (SCI-Expanded, Scopus)

Papers Presented at Peer-Reviewed Scientific Conferences 23

1. EFFECT OF THE GLUT1 INHIBITOR WZB117 ON MDA-MB 231 HUMAN BREAST CANCER

Koca F. M., Nisari M., Bitgen N., Al Ö., Uçar S., Taştan M., et al.

6. ULUSLARARASI KAPADOKYA BİLİMSEL ARAŞTIRMALAR KONGRESİ, Nevşehir, Turkey, 10 - 12 August 2024, pp.4-5, (Summary Text)

2. Antiproliferative Effects of Dosetaxel, Quercetin, And Folic Acid On Pc-3 Prostat Cancer Cells

Aydın F., Önder G. Ö., Bitgen N.

6. International Dicle Scientific Research and Innovation Congress, Diyarbakır, Turkey, 25 - 26 May 2024, pp.277-278, (Summary Text)

3. Evaluation of The Effect of Hesperidin and Cisplatin on Mda-Mb-231 Breast Cancer Cell Line

Aydın F., Önder G. Ö., Baran M., Bitgen N.

6. International Dicle Scientific Research and Innovation Congress, Diyarbakır, Turkey, 25 - 26 May 2024, pp.266-276, (Full Text)

4. Apoptotic Effect of Dexamethasone On Mda-Mb231 Human Breast Cancer Cell Line

Bitgen N., Akkuş A., Önal M. G.

13th International Medicine and Health Sciences Researches Congress, Ankara, Turkey, 26 - 27 August 2023, pp.1004-1010, (Full Text)

5. Paklitaksel ve Melatonin’in Ovcar-3 Over Kanser Hücrelerine Kombine Etkisi; İn Vitro Çalışma

Bitgen N.

10. ULUSLARARASI HIPOKRAT TIP VE SAĞLIK BİLİMLERİ KONGRESİ, İstanbul, Turkey, 16 - 17 December 2022, pp.29, (Summary Text)

6. THE EFFECT OF MELISSA OFFICINALIS L. ON MDA-MB-231 BREAST CANCER CELL LINE

BİTGEN N., BARAN M., ÖNDER G. Ö., GÜRBÜZ P., YAY A. H.

9. INTERNATIONAL GEVHER NESIBE HEALTH SCIENCES CONFERENCE, Kayseri, Turkey, 10 June 2022, (Full Text)

7. Anticancer Effect of a Benzimidazole salt on Aggresive mouse Breast Cancer Cells

Çakır M., Akkoç S., Özkol H., Tülüce Y., Akar S., Bitgen N., et al.

2th International Aegean Heath Areas Symposium, 7 - 08 March 2022, pp.16-17, (Summary Text) Sustainable Development

8. Cushingli hastalardaki kromozomal DNA hasarının mortalite ve morbidite riski açısından Önemi

Bayram F., Bitgen N., Altın-Çelik P., Hamurcu Z., Kurtsoy A., Altuntaş H.

41. Türkiye Endokrinoloji ve Metabolizma Hastalıkları Kongresi, Antalya, Turkey, 27 April - 01 May 2019, pp.255-256, (Full Text)

9. THE EFFECT OF TUMOR MICRO ENVIRONMENT ATP ON CISPLATIN IN CANCER CELL LINE

BİTGEN N., ÖNAL M. G., CANER A.

International Hippocrates Congress on Medical and Health Sciences, 1 - 03 March 2019, (Full Text) Sustainable Development

10. Sitoplazmik Kalsiyum Birikmesine Kanser Hücrelerinin Tepkisi

CANER A., BİTGEN N.

7. ULUSAL MOLEKÜLER BIYOLOJI VE BIYOTEKNOLOJI KONGRESI, Turkey, 2 - 05 July 2018, (Summary Text) Sustainable Development

11. THE EFFECT OF SODIUM ORTHO-VANADATE ON THE APOPTOSIS OF TUMOR CELLS

BİTGEN N., CANER A.

2. international scientific and vocational studies congress, 5 - 08 July 2018, (Summary Text)

12. Tiroid nodüllü hastalarda artan mikronukleus sıklığı ile 8 OHDG seviyeleri ve kanserle ilişkisi

BAYRAM F., ALTUNTAŞ H., BİTGEN N., BAŞKOL G., diri h., Ata s., et al.

38. Türkiye Endokrinoloji ve Metabolizma Hastalıkları Kongresi, Turkey, 11 - 15 May 2016, pp.169, (Summary Text) Sustainable Development

13. Akut organofosfat zehirlenmelerinde kromozomal ve oksidatif DNA hasarı ve bu hasarın adrenal hipofiz ve tiroit hormonları ile ilişkisinin değerlendirilmesi

GÜNDOĞAN K., ALTUNTAŞ H., BAYRAM F., COŞKUN R., BAŞKOL G., BİTGEN N., et al.

12. Ulusal Dahili ve Cerrahi Bilimler Yoğun Bakım Kongresi, Turkey, 4 - 07 November 2015, pp.66, (Summary Text)

14. Obez kişilerde kromozom hasarı, sitostazi, sitotoksisite ve oksidatif DNA hasarının ve BKİ ile ilişkisinin değerlendirilmesi

BAYRAM F., ALTUNTAŞ H., Sahin F., BİTGEN N., HAMURCU Z., ARIBAŞ S., et al.

36. Türkiye Endokrinoloji ve Metabolizma Hastalıkları Kongresi, Antalya, Turkey, 21 - 25 May 2014, pp.17, (Full Text)

15. Non-fonksiyone adenomlu hastalarda kanser riski açısından genom instabilitesinin araştırılması

BAYRAM F., BİTGEN N., ALTUNTAŞ H., KURTSOY A., HAMURCU Z., TUCER B., et al.

9.Hipofiz Sempozyumu, Ankara, Turkey, 9 - 10 November 2013, pp.3, (Full Text) Sustainable Development

16. Increased genom instability and Oxidative DNA damage in active acromegalic patients

BAYRAM F., Bitgen N., ALTUNTAŞ H., Cakir İ., HAMURCU Z., KURTSOY A., et al.

The Endocrine Society’s 95th Annual Meeting & Expo, San Francisco, United States Of America, 15 - 18 June 2013, pp.183, (Full Text)

17. Obez Hastalarda Artan DNA Hasarının Malignite Riski Açısından Önemi

BAYRAM F., Şahin F., ALTUNTAŞ H., BİTGEN N., GÜNDOĞAN K., ARIBAŞ S., et al.

35. Türkiye Endokrinoloji ve Metabolizma Hastalıkları Kongresi & Hipofiz Sempozyumu, Antalya, Turkey, 15 - 19 April 2013, pp.166, (Full Text)

18. Akromegalili Hastalarda Oksidatif DNA Hasarı ve Sitotoksitenin Değerlendirilmesi

BAYRAM F., BİTGEN N., ALTUNTAŞ H., BAŞKOL G., HAMURCU Z., ÇAKIR İ., et al.

34. Türkiye Endokrinoloji ve Metabolizma Hastalıkları Kongresi, Antalya, Turkey, 11 - 15 April 2012, pp.14, (Full Text)

19. Sağlıklı Kişilerdeki DNA Hasarının Sigara Kullanma, Yaş ve Cinsiyete Göre Araştırılması

ALTUNTAŞ H., BİTGEN N.

XII. Ulusal Tıbbi Biyoloji ve Genetik Kongresi, Antalya, Turkey, 27 - 30 October 2011, pp.142, (Full Text)

20. Akromegalili Hastaların Lenfositlerinde Artan Apoptotik ve Nekrotik Hücre Değerleri

BİTGEN N., BAYRAM F., ÇAKIR İ., HAMURCU Z., Şahin F., KURTSOY A., et al.

XII. Ulusal Tıbbi Biyoloji ve Genetik Kongresi, Antalya, Turkey, 27 - 30 October 2011, pp.102-103, (Full Text)

21. Prolaktinomalı hastaların mitojenle uyarılmış lenfositlerinde DNA hasarının kanser riski açısından araştırılması

ÇAKIR İ., Bitgen N., ALTUNTAŞ H., HAMURCU Z., Mert M., KURTSOY A., et al.

33. Türkiye Endokrinoloji ve Metabolizma Hastalıkları Kongresi, Antalya, Turkey, 12 - 16 October 2011, pp.184, (Full Text) Sustainable Development

22. Akromegali hastalarında kanser riski açısından genom instabilitesinin araştırılması

BİTGEN N., BAYRAM F., ÇAKIR İ., HAMURCU Z., Mert M., Şahin F., et al.

33. Türkiye Endokrinoloji ve Metabolizma Hastalıkları Kongresi, Antalya, Turkey, 12 - 16 October 2011, pp.3, (Full Text) Sustainable Development

23. A relation between the AgNORs motifs and T lymphocyte subgroups in phytohemagglutinin-stimulated human T lymphocytes

BİTGEN N., ALTUNTAŞ H., HAMURCU Z., DEMİRTAŞ H., Öztürk F.

European Biotechnology Congress, İstanbul, Turkey, 28 September - 01 October 2011, vol.22, no.1, pp.115, (Full Text)

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