Education Information
2013 - 2018
2013 - 2018Doctorate
Hacettepe University, Sağlık Bilimleri Enstitüsü, Farmasötik Toksikoloji, Turkey
2008 - 2013
2008 - 2013Undergraduate
Erciyes University, Eczacılık Fakültesi, Eczacılık Bölümü, Turkey
Dissertations
2018
2018Doctorate
FLURBİPROFENİN SİTOTOKSİK, GENOTOKSİK VE APOPTOTİK ETKİLERİNİN DEĞERLENDİRİLMESİ
Hacettepe Üniversitesi
Foreign Languages
B2 Upper Intermediate
B2 Upper IntermediateEnglish
Certificates, Courses and Trainings
2019
2019Basic Molecular Biology Techniques Course, Western Blot, RT-PCR
Health&Medicine
Ziya Eren İlaç Uygulama ve Araştırma Merkezi
2019
2019Recent Developments and the Use of Non-Invasive Samples in Comet Assay
Health&Medicine
10th International Congress of the Turkish Society of Toxicology
2019
2019GLP (Good Laboratory Practices / İLU (İyi Laboratuvar Uygulamaları)
Quality Management
The Swiss Consulting/ERFARMA
2017
2017"LCMS-8040" Kullanıcı Eğitimi
Health&Medicine
Ant Teknik
2016
2016"GCMS"
Health&Medicine
Ant Teknik
2016
2016IV. Uygulamalı Temel Hücre Kültürü Teknikleri Kursu
Health&Medicine
GENKÖK
2016
2016"HPLC"
Health&Medicine
Ant Teknik
2015
2015Oxidants and Antioxidants
Health&Medicine
TURKHELTOX
2015
2015Genotoxicity and Methods of Analysis
Health&Medicine
TURKHELTOX
2015
2015Eppendorf Pipet Sistemi
Health&Medicine
İncekaralar
2013
2013Deney Hayvanları Kullanım Sertifikası
Health&Medicine
ERSEM
Research Areas
Health Sciences
Pharmacology and Therapeutics
Professional Sciences
Pharmaceutical Toxicology
Academic Titles / Tasks
2020 - Continues
2020 - ContinuesAssistant Professor
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2018 - 2020
2018 - 2020Research Assistant PhD
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2014 - 2018
2014 - 2018Research Assistant
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Managerial Experience
2014 - Continues
2014 - ContinuesInternship Committee Member
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Courses
Published journal articles indexed by SCI, SSCI, and AHCI
2023
2023Hydroxychloroquine induces oxidative stress and impairs fracture healing in rats
Topak D., Gurbuz K., Dogar F., Bakır E., Gürbüz P., Kilinc E., et al.
JOINT DISEASES AND RELATED SURGERY
, vol.34, no.2, pp.346-355, 2023 (SCI-Expanded)
2022
2022Investigation of the toxicity of a glyphosate-based herbicide in a human liver cell line: Assessing the involvement of Nrf2 pathway and protective effects of vitamin E and alpha-lipoic acid
Ünlü Endirlik B., Bakır E., Ökçesiz A., Güler A., Hamurcu Z., Eken A., et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
, vol.96, 2022 (SCI-Expanded)
2021
2021Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ER alpha and Wnt/beta-catenin signaling pathways
Karaca B., Bakır E., Yerer M. B., Cumaoğlu A., Hamurcu Z., Eken A.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
, vol.35, no.11, 2021 (SCI-Expanded)
2021
2021Assessment of the cytotoxic, genotoxic, and apoptotic potential of flurbiprofen in HeLa and HepG2 cell lines
Bakır E., Çal T., Aydın Dilsiz S., Canpınar H., Eken A., Ündeğer Bucurgat Ü.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
, vol.35, no.6, 2021 (SCI-Expanded)
2020
2020Cherry laurel fruit extract counters dimethoate-induced reproductive impairment and testicular apoptosis.
Bakır E., Sarıözkan S., Ünlü Endirlik B., Baldemir Kılıç A., Yay A. H., Cantürk Tan F., et al.
Arhiv za higijenu rada i toksikologiju
, vol.71, no.4, pp.329-338, 2020 (SCI-Expanded)
2019
2019Assessment of perfluoroalkyl substances levels in tap and bottled water samples from Turkey
Ünlü Endirlik B., Bakır E., Boşgelmez İ. İ., Eken A., Narin İ., Gürbay A.
CHEMOSPHERE
, vol.235, pp.1162-1171, 2019 (SCI-Expanded)
2017
2017An Investigation on Protective Effect of Viburnum opulus L. Fruit Extract Against Ischemia/Reperfusion-Induced Oxidative Stress after Lung Transplantation in Rats
Eken A., Yücel O., Boşgelmez İ. İ., Baldemir A., Çubuk S., Cermık A. H., et al.
KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
, vol.23, no.3, pp.437-444, 2017 (SCI-Expanded)
2017
2017Effect of Laurocerasus officinalis Roem. (Cherry Laurel) Fruit on Dimethoate Induced Hepatotoxicity in Rats
EKEN A., Endirlik B., BAKIR E., Baldemir A., YAY A. H., CANTURK F.
KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
, vol.23, no.5, pp.779-787, 2017 (SCI-Expanded)
Articles Published in Other Journals
2024
2024ANTIPROLIFERATIVE AND ANTIOXIDANT EFFECTS OF CARNOSIC ACID ON HUMAN LIVER CANCER CELLS
Akın U. N., Bakır E., Ökçesiz Hacıseyitoğlu A., Eken A.
Sağlık Bilimleri Dergisi
, vol.33, no.1, pp.60-66, 2024 (Peer-Reviewed Journal)
2023
2023Investigation of Dimethoate Toxicity in Rat Brain and Protective Effect of Laurocerasus officinalis Roem. Fruit Extract Against Oxidative Stress, DNA Damage, and Apoptosis Dimetoat Toksisitesinin Sıçan Beyninde Araştırılması ve Laurocerasus officinalis Roem. Meyve Ekstresinin Oksidatif Stres, DNA Hasarı ve Apoptoza Karşı Koruyucu Etkisi
ÜNLÜ ENDİRLİK B., BAKIR E., YAY A. H., CANTÜRK TAN F., Baldemi̇R Kiliç A., EKEN A.
Fabad Journal of Pharmaceutical Sciences
, vol.48, no.1, pp.139-150, 2023 (Scopus)
2023
2023EVALUATION OF ROUNDUP® TOXICITY IN HUMAN LUNG CELLS
Ünlü Endirlik B., Bakır E., Ökçesiz A., Hamurcu Z., Eken A., Gürbay A.
ANKARA UNIVERSITESI ECZACILIK FAKULTESI DERGISI , vol.47, no.1, pp.261-269, 2023 (Scopus)
2022
2022An interdisciplinary overview of α-PVP
Kariper İ. A., Metin A., Büyükbezirci K., Eken A., Bakir E.
REVUE DE MEDECINE LEGALE
, vol.13, pp.131-138, 2022 (Scopus)
2019
2019Evaluation of Cytotoxic Effects of Carnosic Acid Alone and Combination with Cisplatin in HepG2 Cells
Akın U. N., Bakır E., Ökçesiz A., Eken A.
Proceedings , vol.40, no.1, pp.39, 2019 (Peer-Reviewed Journal)
2019
2019Kinazolin türevi bileşiklerin olası sitotoksik etkilerinin endometriyum kanser hücrelerinde araştırılması
Karaca B., BAKIR E., EKEN A.
Journal of Health Sciences
, vol.28, pp.47-51, 2019 (Peer-Reviewed Journal)
2017
2017ESSENTIAL ELEMENT AND METAL CONTENT OF CHERRY LAUREL (LAUROCERASUS OFFICINALIS ROEM.)FRUIT AND SEEDS
Eken A., Baldemir A., Ünlü Endirlik B., Bakır E., İlgün S.
JOURNAL OF HEALTH SCIENCES
, vol.26, pp.1-4, 2017 (Peer-Reviewed Journal)
2017
2017HISTOPATHOLOGICAL EFFECT OF DIMETHOATE ON LUNG OF RAT AND THE PROTECTIVE ROLE OF LAUROCERASUS OFFICINALIS ROEM. (CHERRY LAUREL)FRUIT*
Eken A., Ünlü Endirlik B., Bakır E., Yay A. H., Baldemir Kılıç A.
Sağlık Bilimleri Dergisi , vol.26, no.3, pp.211-215, 2017 (Peer-Reviewed Journal)
2016
2016Dimethoate-induced renal toxicity in rats and the protective/ ameliorative effects of Laurocerasus officinalis Roem. (cherry laurel) fruit extract
Eken A., Ünlü Endirlik B., Bakır E., Baldemir A., Yay A. H.
Macedonian Pharmaceutical Bulletin , vol.62, pp.251-252, 2016 (Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2023
2023EVALUATION OF THE HEPATOPROTECTIVE EFFECTS OF VITAMIN E AND ALPHA-LIPOIC ACID AGAINST DIMETHOATE TOXICITY
Bakır E., Ünlü Endirlik B.
10. INTERNATIONAL GEVHER NESİBE MEDICAL SCIENCES CONFERENCE, Ankara, Turkey, 3 - 05 February 2023, pp.74-75
2020
2020Glifosat Toksisitesine Karşı Çeşitli Antioksidan Maddelerin Koruyucu Etkisinin Karaciğer Hücre Hattında Araştırılması: Ön Çalışma
Ünlü Endirlik B., Bakır E.
5. Uluslararası Hipokrat Tıp ve Sağlık Bilimleri Kongresi, 18 - 19 December 2020, pp.494
2019
2019Evaluation of Cytotoxic Effects of Carnosic Acid Alone and Combination with Cisplatin in HepG2 Cells
Akın U. N., Bakır E., Ökçesiz A., Eken A.
3rd International conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 18 - 20 December 2019
2019
2019Possible cytotoxic effects and molecular mechanisms of tamoxifen and quinazoline derivatives doxazosin, erlotinib on endometrial cancer cells
KARACA B., EKEN A., BAKIR E., AYCAN M. B., CUMAOĞLU A.
10th International Congress of the Turkish Society of Toxicology, 16 - 19 October 2019
2019
2019Evaluation of cytotoxic, genotoxic and apoptotic effects of flurbiprofen in human liver cancer cell line
Bakır E., Çal T., Aydın Dilsiz S., Canpınar H., Eken A., Ündeğer Bucurgat Ü.
10th International Congress of the Turkish Society of Toxicology, Antalya, Turkey, 16 - 19 October 2019, pp.80
2019
2019Apoptotic effects and cell cycle analysis of flurbiprofen in human cervical carcinoma cells
Bakır E., Çal T., Aydın Dilsiz S., Canpınar H., Eken A., Ündeğer Bucurgat Ü.
10th International Congress of the Turkish Society of Toxicology, Antalya, Turkey, 16 - 19 October 2019, pp.151
2018
2018Protective effects of chlorogenic acid and vitamin c against oxıdatıve stress caused by dimethoate in human erythrocytes
EKEN A., BAKIR E., ÖKÇESİZ A.
12th International Symposium on Pharmaceutical Sciences (ISOPS)., Ankara, Turkey, 26 - 29 June 2018, pp.1
2018
2018Cytotoxic and genotoxic effects of flurbiprofen in hela cells.
Bakır E., Aydın S., Eken A., Ündeğer Bucurgat Ü.
12th International Symposium on Pharmaceutical Sciences (ISOPS)., Ankara, Turkey, 26 - 29 June 2018, pp.1
2018
2018INVESTIGATION OF PERFLUOROALKYL SUBSTANCES IN TAP WATER SAMPLES TAKEN FROM SEVERAL PROVINCES IN TURKEY
Ünlü Endirlik B., Bakır E., Boşgelmez I. I., Eken A., Narin I., Gürbay A.
12th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, 26 - 28 June 2018
2016
2016Investigation of potential neurotoxic effects of perfluorooctanoic acid in Balb c mice by evaluating oxidative stress induction and possible protective effects of taurine and coenzyme Q10 in this model system
ÜNLÜ ENDİRLİK B., ÖZGER E., EKEN A., ÖZTÜRK F., GÜRBAY A.
EUROTOX, 4 - 07 September 2016
2016
2016Dimethoate induced renal toxicity in rats and the protective ameliorative effects of Laurocerasus officinalis Roem cherry laurel fruit extract
EKEN A., ÜNLÜ ENDİRLİK B., ÖZGER E., BALDEMİR A., YAY A. H.
6th Congress of Pharmacy in Macedonia, 1 - 05 June 2016
2016
2016Oxidative stress inducing effects of perfluorooctanoic acid in kidneys of mice and possible protective effects of taurine and coenzyme Q10
ÜNLÜ ENDİRLİK B., EKEN A., BAKIR E., Gürbay A.
2nd International Congress of Forensic Toxicology, “Industrial and Environmental Toxicology”, Ankara, Turkey, 26 - 30 May 2016, pp.219
2016
2016DIMETHOATE INDUCED TOXICITY IN RAT BRAIN AND THE AMELIORATIVE EFFECT OF LAUROCERASUS OFFICINALIS ROEM CHERRY LAUREL FRUIT EXTRACT
Eken A., Özger E., Ünlü Endirlik B., Baldemir A., Yay A. H., Cantürk Tan F., et al.
2nd INTERNATIONAL CONGRESS OF FORENSIC TOXICOLOGY, Ankara, Turkey, 26 - 30 May 2016
2015
2015Dimethoate-induced hepatotoxicity in rats and the protective/ameliorative effects of cherry laurel (Laurocerasus officinalis Roem.) fruit
EKEN A., ÜNLÜ ENDİRLİK B., ÖZGER E., BALDEMİR A., YAY A. H., CANTÜRK F., et al.
9th Congress of the Turkish Society of Toxicology with the participation of the Hellenic Society of Toxicology, TurkHelTox2015 Congress, İzmir, Turkey, 21 - 24 October 2015, vol.0, no.0, pp.42
2015
2015Reproductive Toxicity of Dimethoate In Rats and The Protective/Ameliorative Effects of Cherry Laurel (Laurocerasus Officinalis Roem.) Fruit
Özger E., Eken A., Sarıözkan S., Ünlü Endirlik B., Baldemir A., Yay A. H., et al.
9. Uluslararası Katılımlı Türk Toksikoloji Derneği Kongresi-TURKHELTOX, İzmir, Turkey, 21 - 24 October 2015, vol.0, no.0, pp.43
2015
2015Evaluation of Antioxidant Effects in Rat Liver and Essential Element Contents of Cherry Laurel (Laurocerasus officinalis Roem.)
EKEN A., BALDEMİR A., ÜNLÜ ENDİRLİK B., ÖZGER E., İLGÜN S.
11th International Symposium, on Pharmaceutical Sciences, Ankara, Turkey, 9 - 12 June 2015, vol.1, pp.422-423
Supported Projects
2023 - 2024
2023 - 2024Three Dimensional A549 Spheroid Model Optimization and Comparative Investigation of the Cytotoxic Effect of Titanium Dioxide Nanoparticle in Mono-Layer Cell Culture and Spheroid Cell Model
TUBITAK Project
Bakır E. (Executive), Ökçesiz A., Ünlü Endirlik B., Yılmaz E., Eken A.
2018 - 2020
2018 - 2020Glifosat Bazlı Herbisitlerin Apoptoz İndükleyici Etkisinin İnsan Akciğer ve Karaciğer Hücre Hatlarında Araştırılması
Project Supported by Higher Education Institutions
EKEN A. (Executive), HAMURCU Z., ÜNLÜ ENDİRLİK B., BAKIR E., ÖKÇESİZ A.
2018 - 2020
2018 - 2020
"Kinazolin türevi ilaçların endometriyum kanser hücrelerindeki toksisitesinin ve wntbetakatenin sinyal yolağındaki etkilerinin araştırılması"
Project Supported by Higher Education Institutions
EKEN A. (Executive), CUMAOĞLU A., BAKIR E., KARACA B., AYCAN M. B.
2018 - 2020
2018 - 2020
Kinazolin türevi ilaçların endometrium kanser hücrelerindeki toksisitesinin ve Wnt/beta-katenin yolağındaki etkilerinin araştırılması
Project Supported by Higher Education Institutions
Eken A.(Executive), Aycan M. B., Cumaoğlu A., Bakır E., Karaca B.
2018 - 2019
2018 - 2019In vitro Sistemde Glifosat Bazlı Herbisit Toksisitesinin Değerlendirilmesi
Project Supported by Higher Education Institutions
ÜNLÜ ENDİRLİK B. (Executive), EKEN A., BAKIR E., GÜRBAY A., ÖKÇESİZ A.
2017 - 2018
2017 - 2018
Flurbiprofenin Sitotoksik ve Apoptotik Etkilerinin İnsan Karaciğer Kanser HepG2 Hücrelerinde İn Vitro Değerlendirilmesi
Project Supported by Higher Education Institutions
EKEN A. (Executive), BAKIR E., ÜNDEĞER BUCURGAT Ü.
2017 - 2018
2017 - 2018Türkiye'deki musluk ve şişe sularında bazı perfloroalkilli bileşik düzeylerinin LC-MS/MS ile belirlenmesi
Project Supported by Higher Education Institutions
ÜNLÜ ENDİRLİK B. (Executive), NARİN I., BAKIR E., EKEN A., BOŞGELMEZ I. I., GÜRBAY A.
2013 - 2015
2013 - 2015Dimetoat ile İndüklenen Toksisiteye Karşı Karayemiş (Laurocerasus officinalis Roem.) Meyve Ekstresinin Koruyucu Etkilerinin Sıçanlarda Araştırılması
Project Supported by Higher Education Institutions
EKEN A. (Executive), SARIÖZKAN S., CANTÜRK F., YAY A. H., CANER Y., ÜNLÜ ENDİRLİK B., et al.
Memberships / Tasks in Scientific Organizations
2015 - Continues
2015 - ContinuesFederation of European Toxicology Society (EUROTOX)
Member
2015 - Continues
2015 - ContinuesTURKISH SOCIETY of TOXICOLOGY
Member
2015 - Continues
2015 - ContinuesInternational Union of Toxicology (IUTOX)
Member
Scientific Refereeing
July 2021
July 2021journal Of research in pharmacy
Journal Indexed in ESCI
Awards
December 2019
December 2019Best Oral Presentation Award
3Rd International Conference On Natural Products For Cancer Preventation And Therapy
May 2016
May 2016Poster ödülleri ikincisi
2Nd Internatıonal Congress Of Forensıc Toxıcology
October 2015
October 2015Poster ödülleri üçüncüsü
Turkish Society Of Toxicology With The Participation Of The Hellenic Society Of Toxicology (Turkheltox)
Congress and Symposium Activities
26 February 2024 - 28 February 2024
26 February 2024 - 28 February 2024I. Ulusal Pharmerciyes Eczacılık Kongresi
Attendee
Kayseri-Turkey
03 February 2023 - 05 February 2023
03 February 2023 - 05 February 202310. INTERNATIONAL GEVHER NESİBE MEDICAL SCIENCES CONFERENCE
Attendee
Ankara-Turkey
20 December 2020 - 20 December 2020
20 December 2020 - 20 December 2020Endokrin Bozucular ve Çocuk Sağlığı
Attendee
Ankara-Turkey
01 December 2019 - 01 December 2019
01 December 2019 - 01 December 2019
3rd International Conference of Natural Products for Cancer Prevention and Therapy
Attendee
Kayseri-Turkey
01 October 2019 - 01 October 2019
01 October 2019 - 01 October 201910th International Congress of the Turkish Society of Toxicology
Attendee
Antalya-Turkey
01 November 2018 - 01 November 2018
01 November 2018 - 01 November 2018
Milli İlaç ve Aşı Çalıştayı
Attendee
Kayseri-Turkey
01 June 2018 - 01 June 2018
01 June 2018 - 01 June 201812th International Symposium on Pharmaceutical Sciences (ISOPS)
Attendee
Ankara-Turkey
01 January 2018 - 01 January 2018
01 January 2018 - 01 January 2018HACETTEPE FARMASÖTİK TOKSİKOLOJİ GÜNLERİ-1
Attendee
Ankara-Turkey
01 January 2017 - 01 January 2017
01 January 2017 - 01 January 2017IV. TOKSİKOLOJİ SEMPOZYUMU “Toksikolojide Kariyer Günleri”
Attendee
Eskişehir-Turkey
01 May 2016 - 01 May 2016
01 May 2016 - 01 May 20162nd INTERNATIONAL CONGRESS OF FORENSIC TOXICOLOGY
Attendee
Ankara-Turkey
01 October 2015 - 01 October 2015
01 October 2015 - 01 October 20159th Congress of the Turkish Society of Toxicology with the participation of the Hellenic Society of Toxicology, TurkHelTox
Attendee
İzmir-Turkey
01 May 2014 - 01 May 2014
01 May 2014 - 01 May 2014XI. Türk Eczacılık Tarihi Toplantısı
Attendee
Kayseri-Turkey
01 May 2013 - 01 May 2013
01 May 2013 - 01 May 201319th Annual Conference of the European Association of Faculties of Pharmacy (EAFP)
Attendee
Ankara-Turkey
01 October 2012 - 01 October 2012
01 October 2012 - 01 October 2012