Education Information
2013 - 2018
2013 - 2018Doctorate
Hacettepe University, Sağlık Bilimleri Enstitüsü, Farmasötik Toksikoloji, Turkey
2008 - 2013
2008 - 2013Undergraduate
Erciyes University, Eczacılık Fakültesi, Eczacılık Bölümü, Turkey
Dissertations
2018
2018Doctorate
FLURBİPROFENİN SİTOTOKSİK, GENOTOKSİK VE APOPTOTİK ETKİLERİNİN DEĞERLENDİRİLMESİ
Hacettepe Üniversitesi
Foreign Languages
B2 Upper Intermediate
B2 Upper IntermediateEnglish
Certificates, Courses and Trainings
2019
2019Basic Molecular Biology Techniques Course, Western Blot, RT-PCR
Health&Medicine
Ziya Eren İlaç Uygulama ve Araştırma Merkezi
2019
2019Recent Developments and the Use of Non-Invasive Samples in Comet Assay
Health&Medicine
10th International Congress of the Turkish Society of Toxicology
2019
2019GLP (Good Laboratory Practices / İLU (İyi Laboratuvar Uygulamaları)
Quality Management
The Swiss Consulting/ERFARMA
2017
2017"LCMS-8040" Kullanıcı Eğitimi
Health&Medicine
Ant Teknik
2016
2016"GCMS"
Health&Medicine
Ant Teknik
2016
2016IV. Uygulamalı Temel Hücre Kültürü Teknikleri Kursu
Health&Medicine
GENKÖK
2016
2016"HPLC"
Health&Medicine
Ant Teknik
2015
2015Genotoxicity and Methods of Analysis
Health&Medicine
TURKHELTOX
2015
2015Oxidants and Antioxidants
Health&Medicine
TURKHELTOX
2015
2015Eppendorf Pipet Sistemi
Health&Medicine
İncekaralar
2013
2013Deney Hayvanları Kullanım Sertifikası
Health&Medicine
ERSEM
Research Areas
Health Sciences, Pharmacology and Therapeutics, Professional Sciences, Pharmaceutical Toxicology
Academic Titles / Tasks
2020 - Continues
2020 - ContinuesAssistant Professor
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2018 - 2020
2018 - 2020Research Assistant PhD
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2014 - 2018
2014 - 2018Research Assistant
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Managerial Experience
2014 - Continues
2014 - ContinuesInternship Committee Member
Erciyes University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Courses
Published journal articles indexed by SCI, SSCI, and AHCI
2021
2021Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ER alpha and Wnt/beta-catenin signaling pathways
Karaca B., Bakır E. , Yerer M. B. , Cumaoğlu A. , Hamurcu Z. , Eken A.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, vol.35, no.11, 2021 (Journal Indexed in SCI)
2021
2021Assessment of the cytotoxic, genotoxic, and apoptotic potential of flurbiprofen in HeLa and HepG2 cell lines
Bakır E. , Çal T., Aydın Dilsiz S., Canpınar H., Eken A. , Ündeğer Bucurgat Ü.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, vol.35, no.6, 2021 (Journal Indexed in SCI)
2020
2020Cherry laurel fruit extract counters dimethoate-induced reproductive impairment and testicular apoptosis.
Bakır E. , Sarıözkan S. , Ünlü Endirlik B. , Baldemir Kılıç A., Yay A. H. , Cantürk Tan F. , et al.
Arhiv za higijenu rada i toksikologiju, vol.71, no.4, pp.329-338, 2020 (Journal Indexed in SCI Expanded)
2019
2019Assessment of perfluoroalkyl substances levels in tap and bottled water samples from Turkey
Ünlü Endirlik B. , Bakır E. , Boşgelmez İ. İ. , Eken A. , Narin İ. , Gürbay A.
CHEMOSPHERE, vol.235, pp.1162-1171, 2019 (Journal Indexed in SCI)
2017
2017An Investigation on Protective Effect of Viburnum opulus L. Fruit Extract Against Ischemia/Reperfusion-Induced Oxidative Stress after Lung Transplantation in Rats
Eken A. , Yücel O., Boşgelmez İ. İ. , Baldemir A. , Çubuk S., Cermık A. H. , et al.
KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, vol.23, no.3, pp.437-444, 2017 (Journal Indexed in SCI)
2017
2017Effect of Laurocerasus officinalis Roem. (Cherry Laurel) Fruit on Dimethoate Induced Hepatotoxicity in Rats
EKEN A. , Endirlik B. , BAKIR E. , Baldemir A., YAY A. H. , CANTURK F.
KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, vol.23, no.5, pp.779-787, 2017 (Journal Indexed in SCI)
Articles Published in Other Journals
2019
2019Evaluation of Cytotoxic Effects of Carnosic Acid Alone and Combination with Cisplatin in HepG2 Cells
Akın U. N. , Bakır E. , Ökçesiz A. , Eken A.
Proceedings, vol.40, no.1, pp.39, 2019 (Refereed Journals of Other Institutions)
2019
2019Kinazolin türevi bileşiklerin olası sitotoksik etkilerinin endometriyum kanser hücrelerinde araştırılması
Karaca B., BAKIR E. , EKEN A.
Journal of Health Sciences, vol.28, pp.47-51, 2019 (Other Refereed National Journals)
2017
2017ESSENTIAL ELEMENT AND METAL CONTENT OF CHERRY LAUREL (LAUROCERASUS OFFICINALIS ROEM.) FRUIT AND SEEDS
EKEN A. , BALDEMİR A. , ÜNLÜ ENDİRLİK B. , BAKIR E. , İLGÜN S.
Sağlık Bilimleri Dergisi, vol.26, pp.1-4, 2017 (National Refreed University Journal)
Refereed Congress / Symposium Publications in Proceedings
2020
2020Glifosat Toksisitesine Karşı Çeşitli Antioksidan Maddelerin Koruyucu Etkisinin Karaciğer Hücre Hattında Araştırılması: Ön Çalışma
Ünlü Endirlik B. , Bakır E.
5. Uluslararası Hipokrat Tıp ve Sağlık Bilimleri Kongresi, 18 - 19 December 2020, pp.494
2019
2019Evaluation of Cytotoxic Effects of Carnosic Acid Alone and Combination with Cisplatin in HepG2 Cells
Akın U. N. , Bakır E. , Ökçesiz A. , Eken A.
3rd International conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 18 - 20 December 2019
2019
2019Possible cytotoxic effects and molecular mechanisms of tamoxifen and quinazoline derivatives doxazosin, erlotinib on endometrial cancer cells
KARACA B., EKEN A. , BAKIR E. , AYCAN M. B. , CUMAOĞLU A.
10th International Congress of the Turkish Society of Toxicology, 16 - 19 October 2019
2019
2019Evaluation of cytotoxic, genotoxic and apoptotic effects of flurbiprofen in human liver cancer cell line
Bakır E. , Çal T., Aydın Dilsiz S., Canpınar H., Eken A. , Ündeğer Bucurgat Ü.
10th International Congress of the Turkish Society of Toxicology, Antalya, Turkey, 16 - 19 October 2019, pp.80
2019
2019Apoptotic effects and cell cycle analysis of flurbiprofen in human cervical carcinoma cells
Bakır E. , Çal T., Aydın Dilsiz S., Canpınar H., Eken A. , Ündeğer Bucurgat Ü.
10th International Congress of the Turkish Society of Toxicology, Antalya, Turkey, 16 - 19 October 2019, pp.151
2018
2018Protective effects of chlorogenic acid and vitamin c against oxıdatıve stress caused by dimethoate in human erythrocytes
EKEN A. , BAKIR E. , ÖKÇESİZ A.
12th International Symposium on Pharmaceutical Sciences (ISOPS)., Ankara, Turkey, 26 - 29 June 2018, pp.1
2018
2018Cytotoxic and genotoxic effects of flurbiprofen in hela cells.
Bakır E. , Aydın S., Eken A. , Ündeğer Bucurgat Ü.
12th International Symposium on Pharmaceutical Sciences (ISOPS)., Ankara, Turkey, 26 - 29 June 2018, pp.1
2018
2018INVESTIGATION OF PERFLUOROALKYL SUBSTANCES IN TAP WATER SAMPLES TAKEN FROM SEVERAL PROVINCES IN TURKEY
Ünlü Endirlik B., Bakır E. , Boşgelmez I. I. , Eken A., Narin I. , Gürbay A.
12th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, 26 - 28 June 2018
2016
2016Investigation of potential neurotoxic effects of perfluorooctanoic acid in Balb c mice by evaluating oxidative stress induction and possible protective effects of taurine and coenzyme Q10 in this model system
ÜNLÜ ENDİRLİK B. , ÖZGER E. , EKEN A., ÖZTÜRK F. , GÜRBAY A.
EUROTOX, 4 - 07 September 2016
2016
2016Dimethoate induced renal toxicity in rats and the protective ameliorative effects of Laurocerasus officinalis Roem cherry laurel fruit extract
EKEN A., ÜNLÜ ENDİRLİK B. , ÖZGER E. , BALDEMİR A., YAY A. H.
6th Congress of Pharmacy in Macedonia, 1 - 05 June 2016
2016
2016Oxidative stress inducing effects of perfluorooctanoic acid in kidneys of mice and possible protective effects of taurine and coenzyme Q10
ÜNLÜ ENDİRLİK B. , EKEN A. , BAKIR E. , Gürbay A.
2nd International Congress of Forensic Toxicology, “Industrial and Environmental Toxicology”, Ankara, Turkey, 26 - 30 May 2016, pp.219
2016
2016DIMETHOATE INDUCED TOXICITY IN RAT BRAIN AND THE AMELIORATIVE EFFECT OF LAUROCERASUS OFFICINALIS ROEM CHERRY LAUREL FRUIT EXTRACT
Eken A., Özger E. , Ünlü Endirlik B. , Baldemir A., Yay A. H. , Cantürk Tan F. , et al.
2nd INTERNATIONAL CONGRESS OF FORENSIC TOXICOLOGY, Ankara, Turkey, 26 - 30 May 2016
2015
2015Dimethoate-induced hepatotoxicity in rats and the protective/ameliorative effects of cherry laurel (Laurocerasus officinalis Roem.) fruit
EKEN A. , ÜNLÜ ENDİRLİK B. , ÖZGER E. , BALDEMİR A. , YAY A. H. , CANTÜRK F. , et al.
9th Congress of the Turkish Society of Toxicology with the participation of the Hellenic Society of Toxicology, TurkHelTox2015 Congress, İzmir, Turkey, 21 - 24 October 2015, vol.0, no.0, pp.42
2015
2015Reproductive Toxicity of Dimethoate In Rats and The Protective/Ameliorative Effects of Cherry Laurel (Laurocerasus Officinalis Roem.) Fruit
Özger E. , Eken A. , Sarıözkan S. , Ünlü Endirlik B. , Baldemir A. , Yay A. H. , et al.
9. Uluslararası Katılımlı Türk Toksikoloji Derneği Kongresi-TURKHELTOX, İzmir, Turkey, 21 - 24 October 2015, vol.0, no.0, pp.43
2015
2015Evaluation of Antioxidant Effects in Rat Liver and Essential Element Contents of Cherry Laurel (Laurocerasus officinalis Roem.)
EKEN A. , BALDEMİR A. , ÜNLÜ ENDİRLİK B. , ÖZGER E. , İLGÜN S.
11th International Symposium, on Pharmaceutical Sciences, Ankara, Turkey, 9 - 12 June 2015, vol.1, pp.422-423
2014
2014Karayemiş (Laurocerasus officinalis M. Roem.) Meyve ve Çekirdeğinin Metal Düzeylerinin ICP-MS ile Belirlenmesi
EKEN A. , BALDEMİR A. , ÜNLÜ ENDİRLİK B. , ÖZGER E. , İLGÜN S. , Delimustafaoğlu F.
21. Bitkisel İlaç Hammaddeleri Toplantısı, Nevşehir, Turkey, 28 May - 01 June 2014, pp.44
Supported Projects
2018 - 2020
2018 - 2020Glifosat Bazlı Herbisitlerin Apoptoz İndükleyici Etkisinin İnsan Akciğer ve Karaciğer Hücre Hatlarında Araştırılması
Project Supported by Higher Education Institutions
EKEN A. (Executive) , HAMURCU Z. , ÜNLÜ ENDİRLİK B. , BAKIR E. , ÖKÇESİZ A.
2018 - 2020
2018 - 2020
"Kinazolin türevi ilaçların endometriyum kanser hücrelerindeki toksisitesinin ve wntbetakatenin sinyal yolağındaki etkilerinin araştırılması"
Project Supported by Higher Education Institutions
EKEN A. (Executive) , CUMAOĞLU A. , BAKIR E. , KARACA B., AYCAN M. B.
2018 - 2020
2018 - 2020
Kinazolin türevi ilaçların endometrium kanser hücrelerindeki toksisitesinin ve Wnt/beta-katenin yolağındaki etkilerinin araştırılması
Project Supported by Higher Education Institutions
Eken A.(Executive), Aycan M. B. , Cumaoğlu A., Bakır E. , Karaca B.
2018 - 2019
2018 - 2019In vitro Sistemde Glifosat Bazlı Herbisit Toksisitesinin Değerlendirilmesi
Project Supported by Higher Education Institutions
ÜNLÜ ENDİRLİK B. (Executive) , EKEN A. , BAKIR E. , GÜRBAY A., ÖKÇESİZ A.
2017 - 2018
2017 - 2018
Flurbiprofenin Sitotoksik ve Apoptotik Etkilerinin İnsan Karaciğer Kanser HepG2 Hücrelerinde İn Vitro Değerlendirilmesi
Project Supported by Higher Education Institutions
EKEN A. (Executive) , BAKIR E. , ÜNDEĞER BUCURGAT Ü.
2017 - 2018
2017 - 2018Türkiye'deki musluk ve şişe sularında bazı perfloroalkilli bileşik düzeylerinin LC-MS/MS ile belirlenmesi
Project Supported by Higher Education Institutions
ÜNLÜ ENDİRLİK B. (Executive) , NARİN I. , BAKIR E. , EKEN A. , BOŞGELMEZ I. I. , GÜRBAY A.
2013 - 2015
2013 - 2015Dimetoat ile İndüklenen Toksisiteye Karşı Karayemiş (Laurocerasus officinalis Roem.) Meyve Ekstresinin Koruyucu Etkilerinin Sıçanlarda Araştırılması
Project Supported by Higher Education Institutions
EKEN A. (Executive) , SARIÖZKAN S. , CANTÜRK F. , YAY A. H. , CANER Y. , ÜNLÜ ENDİRLİK B. , et al.
Memberships / Tasks in Scientific Organizations
2015 - Continues
2015 - ContinuesTURKISH SOCIETY of TOXICOLOGY
Member
2015 - Continues
2015 - ContinuesInternational Union of Toxicology (IUTOX)
Member
2015 - Continues
2015 - ContinuesFederation of European Toxicology Society (EUROTOX)
Member
Scientific Refereeing
July 2021
July 2021journal Of research in pharmacy
Journal Indexed in ESCI
Awards
December 2019
December 2019Best Oral Presentation Award
3Rd International Conference On Natural Products For Cancer Preventation And Therapy
May 2016
May 2016Poster ödülleri ikincisi
2Nd Internatıonal Congress Of Forensıc Toxıcology
October 2015
October 2015Poster ödülleri üçüncüsü
Turkish Society Of Toxicology With The Participation Of The Hellenic Society Of Toxicology (Turkheltox)
Edit Congress and Symposium Activities
2020
2020Endokrin Bozucular ve Çocuk Sağlığı
Attendee
Ankara-Turkey
2019
2019
3rd International Conference of Natural Products for Cancer Prevention and Therapy
Attendee
Kayseri-Turkey
2019
201910th International Congress of the Turkish Society of Toxicology
Attendee
Antalya-Turkey
2018
2018
Milli İlaç ve Aşı Çalıştayı
Attendee
Kayseri-Turkey
2018
201812th International Symposium on Pharmaceutical Sciences (ISOPS)
Attendee
Ankara-Turkey
2018
2018HACETTEPE FARMASÖTİK TOKSİKOLOJİ GÜNLERİ-1
Attendee
Ankara-Turkey
2017
2017IV. TOKSİKOLOJİ SEMPOZYUMU “Toksikolojide Kariyer Günleri”
Attendee
Eskişehir-Turkey
2016
20162nd INTERNATIONAL CONGRESS OF FORENSIC TOXICOLOGY
Attendee
Ankara-Turkey
2015
20159th Congress of the Turkish Society of Toxicology with the participation of the Hellenic Society of Toxicology, TurkHelTox
Attendee
İzmir-Turkey
2014
2014XI. Türk Eczacılık Tarihi Toplantısı
Attendee
Kayseri-Turkey
2013
201319th Annual Conference of the European Association of Faculties of Pharmacy (EAFP)
Attendee
Ankara-Turkey
2012
2012