Eğitim Bilgileri
2023 - Devam Ediyor
2023 - Devam EdiyorPost Doktora
Martin-Luther-Universitaet Halle-Wittenberg, Institute of Pharmacy, Pharmaceutical Chemistry and Clinical Pharmacy, Almanya
2014 - 2020
2014 - 2020Doktora
Ankara Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya, Türkiye
2009 - 2014
2009 - 2014Lisans
Erciyes Üniversitesi, Eczacılık Fakültesi, Eczacılık, Türkiye
Yabancı Diller
B2 Orta Üstü
B2 Orta Üstüİngilizce
Araştırma Alanları
Eczacılık
Farmasötik Kimya
Akademik Unvanlar / Görevler
2022 - Devam Ediyor
2022 - Devam EdiyorDoç. Dr.
Erciyes Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2015 - 2022
2015 - 2022Araştırma Görevlisi
Erciyes Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
2024
2024Synergistic effect of potential alpha-amylase inhibitors from Egyptian propolis with acarbose using in silico and in vitro combination analysis
Nada A. A., Metwally A. M., Asaad A. M., ÇELİK İ., Ibrahim R. S., Eldin S. M. S.
BMC Complementary Medicine and Therapies , cilt.24, sa.1, 2024 (SCI-Expanded)
2024
2024In vitro anti-Helicobacter pylori, anti-urease and anti-gastric cancer activities of novel hydrazones
Maryam Z., Kaya B., BOSTANCI H. E., Kısa D., ÇELİK İ., ACAR ÇEVİK U., et al.
Journal of Molecular Structure , cilt.1307, 2024 (SCI-Expanded)
2024
2024Synthesis, DFT Calculations, <i>In Silico</i> Studies, and Antimicrobial Evaluation of Benzimidazole-Thiadiazole Derivatives
Isik A., ACAR ÇEVİK U., Karayel A., Ahmad I., Patel H., ÇELİK İ., et al.
ACS OMEGA , sa.16, ss.18469-18479, 2024 (SCI-Expanded)
2024
2024Investigating Potential Cancer Therapeutics: Insight into Histone Deacetylases (HDACs) Inhibitions.
Ahmad B., Saeed A., Al-Amery A., Celik İ., Ahmed I., Yaseen M., et al.
Pharmaceuticals (Basel, Switzerland) , cilt.17, sa.4, 2024 (SCI-Expanded)
2024
2024New Benzimidazole-Triazole Derivatives as Topoisomerase I Inhibitors: Design, Synthesis, Anticancer Screening, and Molecular Modeling Studies
Çevik U. A., Kaya B., ÇELİK İ., Rudrapal M., Rakshit G., Karayel A., et al.
ACS Omega , sa.11, ss.13359-13372, 2024 (SCI-Expanded)
2024
2024Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer
Abbade Y., KIŞLA M. M., Hassan M. A., ÇELİK İ., DOĞAN T., MUTLU P., et al.
ACS Omega , cilt.9, sa.8, ss.9547-9563, 2024 (SCI-Expanded)
2024
2024Detection of natural compounds by virtual screening, molecular docking and dynamics studies and evaluation of their effects on tau level <i>in vitro</i> Alzheimer's model
UZUNHİSARCIKLI E., ÇELİK İ., Yerer M. B.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.42, sa.1, ss.384-392, 2024 (SCI-Expanded)
2024
2024Attenuation of quorum sensing regulated virulence functions and biofilm of pathogenic bacteria by medicinal plant Artemisia annua and its phytoconstituent 1, 8-cineole
Khan M. A., Shahid M., ÇELİK İ., Khan H. M., Shahzad A., Husain F. M., et al.
Microscopy Research and Technique , cilt.87, sa.1, ss.133-148, 2024 (SCI-Expanded)
2024
2024Molecular insights into the anti-inflammatory activity of fermented pineapple juice using multimodal computational studies
Tallei T. E., Fatimawali F., Adam A. A., Ekatanti D., ÇELİK İ., Fatriani R., et al.
Archiv der Pharmazie , cilt.357, sa.1, 2024 (SCI-Expanded)
2024
2024Design, synthesis, and molecular docking studies of benzimidazole-1,3,4-triazole hybrids as carbonic anhydrase I and II inhibitors
ÇELİK İ., ACAR ÇEVİK U., Küçükoğlu K., NADAROĞLU H., BOSTANCI H. E., Işık A., et al.
Chemical Biology and Drug Design , cilt.103, sa.1, 2024 (SCI-Expanded)
2023
2023Antibiofilm and anti-quorum sensing activity of Psidium guajava L. leaf extract: In vitro and in silico approach.
Khan M. A., Celik İ., Khan H. M., Shahid M., Shahzad A., Kumar S., et al.
PloS one , cilt.18, sa.12, 2023 (SCI-Expanded)
2023
2023Interaction mechanism of a pesticide, Azoxystrobin with bovine serum albumin: Assessments through fluorescence, UV-Vis absorption, electrochemical and molecular docking simulation techniques.
Erkmen C., Celik İ.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy , cilt.308, ss.123719, 2023 (SCI-Expanded)
2023
2023Computational biology and in vitro studies for anticipating cancer-related molecular targets of sweet wormwood (Artemisia annua)
Dawood H., ÇELİK İ., Ibrahim R. S.
BMC Complementary Medicine and Therapies , cilt.23, sa.1, 2023 (SCI-Expanded)
2023
2023Deciphering the putative bioactive metabolites and the underlying mechanism of Juniperus horizontalis Moench (Creeping juniper) in the treatment of inflammation using network pharmacology and molecular docking.
El-Banna A. A., Shawky E., Celik İ., Ghareeb D. A., Abdulmalek S. A., Darwish R. S.
The Journal of pharmacy and pharmacology , 2023 (SCI-Expanded)
2023
2023In vitro and in silico guided identification of antimalarial phytoconstituent(s) in the root of Citrus maxima (Burm.) Merr.
Gogoi N., Rudrapal M., Celik İ., Kaishap P. P., Chetia D.
Journal of biomolecular structure & dynamics , ss.1-12, 2023 (SCI-Expanded)
2023
2023Synthesis of novel pyrazolone candidates with studying some biological activities and in-silico studies.
Abdellattif M. H., Hamed E. O., Elhoseni N. K. R., Assy M. G., Emwas A. M., Jaremko M., et al.
Scientific reports , cilt.13, sa.1, ss.19170, 2023 (SCI-Expanded)
2023
2023Design, synthesis, molecular docking and molecular dynamic studies of novel benzimidazole-thiazole derivatives as potent and selective COX-2 inhibitors
IRMAK N. E., SAĞLIK B. N., ÇELİK İ., Tahsin Sen H., ÖZKAY Y., KILCIGİL G.
New Journal of Chemistry , cilt.47, sa.47, ss.21620-21632, 2023 (SCI-Expanded)
2023
2023An integrated strategy combining UPLC-MS/MS, chemometrics, molecular docking, and molecular dynamics simulation for metabolic profiling of onion (Allium cepa L.) cultivars and unravelling potential anti-COVID-19 metabolites
Elattar M. M., Hammoda H. M., Ghareeb D. A., El-Hosseny M. F., Seadawy M. G., ÇELİK İ., et al.
South African Journal of Botany , cilt.162, ss.885-900, 2023 (SCI-Expanded)
2023
2023Effects of algerian nettle (Urtica dioica L.) on benign prostatic hyperplasia and their mechanism of action elucidation: in vivo and in silico approaches.
Bougueroua K., Boufadi M. Y., Latreche B., Celik İ., Guerrero Gonzalez M., Doubbi Bounoua A., et al.
Natural product research , ss.1-11, 2023 (SCI-Expanded)
2023
2023The depsidones from marine sponge-derived fungus Aspergillus unguis IB151 as an anti-MRSA agent: Molecular docking, pharmacokinetics analysis, and molecular dynamic simulation studies
Handayani D., Aminah I., Pontana Putra P., Eka Putra A., Arbain D., Satriawan H., et al.
Saudi Pharmaceutical Journal , cilt.31, sa.9, 2023 (SCI-Expanded)
2023
2023Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical Implications.
Kciuk M., Alam M., Ali N., Rashid S., Głowacka P., Sundaraj R., et al.
Molecules (Basel, Switzerland) , cilt.28, sa.13, 2023 (SCI-Expanded)
2023
2023Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides as an Important Scaffold for Anticancer Drug Discovery-In Vitro and In Silico Evaluation.
Kciuk M., Marciniak B., Celik İ., Zerroug E., Dubey A., Sundaraj R., et al.
International journal of molecular sciences , cilt.24, sa.13, 2023 (SCI-Expanded)
2023
2023Design, synthesis, molecular docking and biological evaluation of 1,2,4-triazole derivatives possessing a hydrazone moiety as anti-breast cancer agents
Tapera M., Kekeçmuhammed H., Tunc C. U., Kutlu A. U., ÇELİK İ., Zorlu Y., et al.
New Journal of Chemistry , cilt.47, sa.24, ss.11602-11614, 2023 (SCI-Expanded)
2023
2023Phytochemical Composition, In Vitro Antimicrobial, Antioxidant, and Enzyme Inhibition Activities, and In Silico Molecular Docking and Dynamics Simulations of Centaurea lycaonica: A Computational and Experimental Approach.
Fatullayev H., Paşayeva L., Celik İ., İnce U., Tugay O.
ACS omega , cilt.8, sa.25, ss.22854-22865, 2023 (SCI-Expanded)
2023
2023Forecasting of potential anti-inflammatory targets of some immunomodulatory plants and their constituents using in vitro, molecular docking and network pharmacology-based analysis.
Khairy A., Ghareeb D. A., Celik İ., Hammoda H. M., Zaatout H. H., Ibrahim R. S.
Scientific reports , cilt.13, sa.1, ss.9539, 2023 (SCI-Expanded)
2023
2023Exploring the structural, photophysical and optoelectronic properties of a diaryl heptanoid curcumin derivative and identification as a SARS-CoV-2 inhibitor
Archana V. P., Armaković S. J., Armaković S., Çelik İ., Bhagyasree J., Dinesh Babu K., et al.
JOURNAL OF MOLECULAR STRUCTURE , cilt.1281, ss.1-16, 2023 (SCI-Expanded)
2023
2023New benzimidazole-oxadiazole derivatives: Synthesis, α-glucosidase, α-amylase activity, and molecular modeling studies as potential antidiabetic agents
ACAR ÇEVİK U., ÇELİK İ., PASHAYEVA L., FATULLAYEV H., BOSTANCI H. E., ÖZKAY Y., et al.
Archiv der Pharmazie , cilt.356, sa.5, 2023 (SCI-Expanded)
2023
2023New imidazole derivatives as aromatase inhibitor: Design, synthesis, biological activity, molecular docking, and computational ADME-Tox studies
Çetiner G., Acar Çevik U., Celik İ., Bostancı H. E., Özkay Y., Kaplancıklı Z. A.
JOURNAL OF MOLECULAR STRUCTURE , cilt.1278, ss.1-9, 2023 (SCI-Expanded)
2023
2023Study of nonlinear optical responses of phytochemicals of Clitoria ternatea by quantum mechanical approach and investigation of their anti-Alzheimer activity with in silico approach
Lakhera S., Devlal K., Rana M., ÇELİK İ.
STRUCTURAL CHEMISTRY , cilt.34, sa.2, ss.439-454, 2023 (SCI-Expanded)
2023
2023Beta Elemene induces cytotoxic effects in FLT3 ITD-mutated acute myeloid leukemia by modulating apoptosis.
Alafnan A., Dogan R., Bender O., Celik İ., Mollica A., Malik J. A., et al.
European review for medical and pharmacological sciences , cilt.27, sa.8, ss.3270-3287, 2023 (SCI-Expanded)
2023
2023Substances of Natural Origin in Medicine: Plants vs. Cancer.
Gielecińska A., Kciuk M., Mujwar S., Celik İ., Kołat D., Kałuzińska-Kołat Ż., et al.
Cells , cilt.12, sa.7, 2023 (SCI-Expanded)
2023
2023Synthesis, biological evaluation, and molecular modeling studies of new 1,3,4-thiadiazole derivatives as potent antimicrobial agents.
Acar Çevik U., Celik İ., İnce U., Maryam Z., Ahmad I., Patel H., et al.
Chemistry & biodiversity , cilt.20, sa.3, 2023 (SCI-Expanded)
2023
2023Design, Synthesis, In Silico and POM Studies for the Identification of the Pharmacophore Sites of Benzylidene Derivatives
Hosen M. I., Mukhrish Y. E., Jawhari A. H., ÇELİK İ., EROL M., Abdallah E. M., et al.
Molecules , cilt.28, sa.6, 2023 (SCI-Expanded)
2023
2023Vanillin-Based Indolin-2-one Derivative Bearing a Pyridyl Moiety as a Promising Anti-Breast Cancer Agent via Anti-Estrogenic Activity
Bender O., ÇELİK İ., Dogan R., ATALAY A., Shoman M. E., Ali T. F. S., et al.
ACS Omega , cilt.8, sa.7, ss.6968-6981, 2023 (SCI-Expanded)
2023
2023Doxorubicin—An Agent with Multiple Mechanisms of Anticancer Activity
Kciuk M., Gielecińska A., Mujwar S., Kołat D., Kałuzińska-Kołat Ż., Celik İ., et al.
CELLS , cilt.12, sa.4, ss.1-30, 2023 (SCI-Expanded)
2023
2023PD-1/PD-L1 and DNA Damage Response in Cancer
Kciuk M., Kołat D., Kałuzińska-Kołat Ż., Gawrysiak M., Drozda R., Çelik İ., et al.
CELLS , cilt.12, sa.4, ss.1-31, 2023 (SCI-Expanded)
2023
2023Computational Investigation of the Interaction of Novel Indene Methylene Analogues with Acetylcholinesterase from Both Dynamic and Thermodynamic Perspectives
Gupta S. M., Jain N. K., Yadav R., Erol M., Celik I., Gupta M., et al.
LETTERS IN DRUG DESIGN & DISCOVERY , cilt.20, sa.12, ss.1911-1921, 2023 (SCI-Expanded)
2023
2023New2-((2-(2,4-dinitrophenyl)hydrazineeylidene) derivatives: design, synthesis, in silico, and in vitro anticancer studies.
Sajjan V. P., Anigol L. B., Gurubasavaraj P. M., Patil D., Patil P. S., Gummagol N. B., et al.
Journal of biomolecular structure & dynamics , cilt.41, sa.21, ss.11681-11699, 2023 (SCI-Expanded)
2023
2023Synthesis, molecular docking, molecular dynamics and evaluation of Drug-Likeness properties of the fused N-Formyl pyrazoline substituted new dehydroepiandrosterone derivatives
Çapan İ., Shehu A., Sert Y., Çelik İ., Erol M., Koca İ., et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.41, sa.6, ss.2492-2503, 2023 (SCI-Expanded)
2023
2023Resveratrol and Its Natural Analogues Inhibit RNA Dependant RNA Polymerase (RdRp) of Rhizopus oryzae in Mucormycosis through Computational Investigations
ÇELİK İ., Rudrapal M., Yadalam P. K., Chinnam S., Balaji T. M., Varadarajan S., et al.
POLYCYCLIC AROMATIC COMPOUNDS , cilt.43, sa.5, ss.4426-4443, 2023 (SCI-Expanded)
2023
2023Design, synthesis, molecular modeling, DFT, ADME and biological evaluation studies of some new 1,3,4-oxadiazole linked benzimidazoles as anticancer agents and aromatase inhibitors
ÇEVİK U. A., ÇELİK İ., Isik A., Ahmad I., Patel H., ÖZKAY Y., et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.41, sa.5, ss.1944-1958, 2023 (SCI-Expanded)
2023
2023Identification and in-vitro analysis of potential proteasome inhibitors targeting PSMβ5 for multiple myeloma
Yadav R., Nath U. K., Celik İ., Handu S., Jain N., Dhamija P.
BIOMEDICINE AND PHARMACOTHERAPY , cilt.157, sa.113963, ss.1-11, 2023 (SCI-Expanded)
2023
2023COMPREHENSIVE ANALYSIS ON COTINUS COGGYGRIA SCOP. LEAVES: PHYTOCHEMICAL CHARACTERIZATION, BIOLOGICAL PROFILE AND DOCKING STUDIES
ŞEKER KARATOPRAK G., Kiliç G., ÇELİK İ., İLGÜN S., KÖNGÜL ŞAFAK E., Koşar M.
Studia Universitatis Babes-Bolyai Chemia , cilt.2023, sa.4, ss.71-92, 2023 (SCI-Expanded)
2023
2023DFT and MD investigations of the biomolecules of phenothiazine derivatives: interactions with gold and water molecules and investigations in search of effective drug for SARS-CoV-2.
Al-Otaibi J. S., Mary Y. S., Mary S., Trivedi R., Chakraborty B., Yadav R., et al.
Journal of biomolecular structure & dynamics , cilt.41, sa.10, ss.4522-4533, 2023 (SCI-Expanded)
2023
2023Computational Simulations Reveal the Synergistic Action of Phytochemicals of Morus alba to Exert Anti-Alzheimer Activity via Inhibition of Acetylcholinesterase and Glycogen Synthase Kinase-3β
Paul A., Zothantluanga J. H., Rakshit G., ÇELİK İ., Rudrapal M., Zaman M. K.
Polycyclic Aromatic Compounds , 2023 (SCI-Expanded)
2023
2023In Vitro and in Silico Evaluation of Some New 1H-Benzimidazoles Bearing Thiosemicarbazide and Triazole as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
ÇELİK İ., Ayhan-Kilcigil G., GÜVEN B., Kara Z., Onay-Besikci A.
POLYCYCLIC AROMATIC COMPOUNDS , cilt.43, sa.1, ss.444-455, 2023 (SCI-Expanded)
2022
2022Benzimidazole-hydrazone derivatives: Synthesis, in vitro anticancer, antimicrobial, antioxidant activities, in silico DFT and ADMET studies
IŞIK A., Acar Çevik U., ÇELİK İ., BOSTANCI H. E., Karayel A., Gündoğdu G., et al.
Journal of Molecular Structure , cilt.1270, 2022 (SCI-Expanded)
2022
2022Synthesis, Molecular Docking, Dynamics, Quantum-Chemical Computation, and Antimicrobial Activity Studies of Some New Benzimidazole-Thiadiazole Hybrids.
Çelik İ., Çevik U. A., Karayel A., Işık A., Kayış U., Gül Ü. D., et al.
ACS omega , cilt.7, sa.50, ss.47015-47030, 2022 (SCI-Expanded)
2022
2022Computational prediction of the effect of mutations in the receptor-binding domain on the interaction between SARS-CoV-2 and human ACE2
Celik İ., Khan A., Dwivany F. M., Wei D., Tallei T. E.
MOLECULAR DIVERSITY , cilt.26, sa.6, ss.3309-3324, 2022 (SCI-Expanded)
2022
2022Synthesis and Molecular Docking of New N-Acyl Hydrazones-Benzimidazole as hCA I and II Inhibitors
Çevik U. A., Küçükoğlu K., Nadaroglu H., Celik İ., Işık A., Bostancı H. E., et al.
MEDICINAL CHEMISTRY , cilt.19, ss.1-6, 2022 (SCI-Expanded)
2022
2022Evaluation of the Chemical Composition, Antioxidant and Antidiabetic Activity of Rhaponticoides iconiensis Flowers: Effects on Key Enzymes Linked to Type 2 Diabetes In Vitro, In Silico and on Alloxan-Induced Diabetic Rats In Vivo.
Paşayeva L., Fatullayev H., Celik I., Unal G., Bozkurt N. M., Tugay O., et al.
Antioxidants (Basel, Switzerland) , cilt.11, sa.11, 2022 (SCI-Expanded)
2022
2022Quantum mechanical, virtual screening, molecular docking, molecular dynamics, ADME and antimicrobial activity studies of some new indole-hydrazone derivatives as potent agents against E. faecalis
EROL M., ÇELİK İ., İNCE U., FATULLAYEV H., UZUNHİSARCIKLI E., PÜSKÜLLÜ M. O.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.40, sa.17, ss.8112-8126, 2022 (SCI-Expanded)
2022
2022Synthesis, characterization, molecular docking, dynamics simulations, and in silico absorption, distribution, metabolism, and excretion (ADME) studies of new thiazolylhydrazone derivatives as butyrylcholinesterase inhibitors
Isik A., ÇEVİK U. A., ÇELİK İ., Ercetin T., KOÇAK A., ÖZKAY Y., et al.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES , cilt.77, sa.11, ss.447-457, 2022 (SCI-Expanded)
2022
2022Discovery of potential natural dihydroorotate dehydrogenase inhibitors and their synergism with brequinar via integrated molecular docking, dynamic simulations and in vitro approach
Khairy A., Hammoda H. M., Celik İ., Zaatout H. H., Ibrahim R. S.
SCIENTIFIC REPORTS , cilt.12, sa.19037, ss.1-30, 2022 (SCI-Expanded)
2022
2022Discovery of oxindole‐based FLT3 inhibitors as a promising therapeutic lead for acute myeloid leukemia carrying the oncogenic ITD mutation
Bender O., Shoman M. E., Ali T. F. S., Dogan R., Çelik İ., Mollica A., et al.
ARCHIV DER PHARMAZIE , cilt.2022, sa.e2200407, ss.1-20, 2022 (SCI-Expanded)
2022
2022Analgesic and Anti-Inflammatory Potential of Indole Derivatives
Rudrapal M., Çelik İ., Chinnam S., Çevik U. A., Tallei T. E., Nizam A., et al.
POLYCYCLIC AROMATIC COMPOUNDS , cilt.0, sa.0, ss.1-22, 2022 (SCI-Expanded)
2022
2022Synthesis and investigations of reactive properties, photophysical properties and biological activities of a pyrazole-triazole hybrid molecule
Karrouchi K., ÇELİK İ., Fettach S., Karthick T., Bougrin K., Radi S., et al.
Journal of Molecular Structure , cilt.1265, 2022 (SCI-Expanded)
2022
2022Synthesis, molecular modeling, 3D-QSAR and biological evaluation studies of new benzimidazole derivatives as potential MAO-A and MAO-B inhibitors
EROL M., ÇELİK İ., Saglik B. N., Karayel A., Mellado M., Mella J.
JOURNAL OF MOLECULAR STRUCTURE , cilt.1265, 2022 (SCI-Expanded)
2022
2022Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects
Kucukoglu K., Cevik U. A., NADAROĞLU H., ÇELİK İ., Isik A., BOSTANCI H. E., et al.
MEDICINAL CHEMISTRY RESEARCH , cilt.31, sa.10, ss.1771-1782, 2022 (SCI-Expanded)
2022
2022Virtual Screening, Molecular Docking, Molecular Dynamics and ADMET Studies on the OTU Protease of Crimean-Congo Hemorrhagic Fever Virus
Yildirim M., Çelik İ.
ChemistrySelect , cilt.7, sa.35, 2022 (SCI-Expanded)
2022
2022Synthesis, and docking studies of novel tetrazole-S-alkyl derivatives as antimicrobial agents
Acar Çevik U., Çelik İ., Işık A., Gül Ü. D., Bayazıt G., Bostancı H. E., et al.
PHOSPHORUS, SULFUR AND SILICON AND THE RELATED ELEMENTS , cilt.0, sa.0, ss.1-8, 2022 (SCI-Expanded)
2022
2022Anti-quorum sensing, antibiofilm, and antibacterial activities of extracts of Centella asiatica L. leaves, and in vitro derived leaves-calli through tissue culture: a potential for biofouling-prevention
Khan M. A., Khan H. M., Ganie I. B., Kumar S., Shahzad A., Celik İ., et al.
BIOFOULING , cilt.38, sa.7, ss.715-728, 2022 (SCI-Expanded)
2022
2022Design, Synthesis, in Vitro and in Silico Studies of Benzimidazole-Linked Oxadiazole Derivatives as Anti-inflammatory Agents
ÇELİK İ., YILMAZ SARIALTIN S., ÇOBAN T., KILCIGİL G.
CHEMISTRYSELECT , cilt.7, sa.28, 2022 (SCI-Expanded)
2022
2022Novel Benzimidazole-Based Compounds as Antimicrobials: Synthesis, Molecular Docking, Molecular Dynamics and in silico ADME Profile Studies
YEŞİLÇAYIR E., ÇELİK İ., Şen H. T., Gürpınar S. S., ERYILMAZ M., Kilcigil G.
Acta chimica Slovenica , cilt.69, sa.2, ss.419-429, 2022 (SCI-Expanded)
2022
2022An Insight Based on Computational Analysis of the Interaction between the Receptor-Binding Domain of the Omicron Variants and Human Angiotensin-Converting Enzyme 2.
Çelik İ., Abdellattif M. H., Tallei T. E.
Biology , cilt.11, sa.5, 2022 (SCI-Expanded)
2022
2022Phytochemical profile, antioxidant, antiproliferative, and enzyme inhibition-docking analyses of Salvia ekimiana Celep & Dogan
Karatoprak G., Goger F., Çelik İ., Budak Ü., Akkol E. K., Aschner M.
SOUTH AFRICAN JOURNAL OF BOTANY , cilt.146, ss.36-47, 2022 (SCI-Expanded)
2022
2022Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies.
Rudrapal M., Celik İ., Chinnam S., Azam Ansari M., Khan J., Alghamdi S., et al.
Saudi journal of biological sciences , cilt.29, sa.5, ss.3456-3465, 2022 (SCI-Expanded)
2022
2022Design, Synthesis, and Molecular Modeling Studies of a Novel Benzimidazole as an Aromatase Inhibitor
Çevik U. A., Celik İ., Mella J., Mellado M., Özkay Y., Kaplancıklı Z. A.
ACS OMEGA , cilt.7, sa.18, ss.16152-16163, 2022 (SCI-Expanded)
2022
2022In VitroandIn SilicoStudies of Quinoline-2-Carbaldehyde Hydrazone Derivatives as Potent Antimicrobial Agents
ÇELİK İ., EROL M., PÜSKÜLLÜ M. O., UZUNHİSARCIKLI E., İNCE U., Kuyucuklu G., et al.
POLYCYCLIC AROMATIC COMPOUNDS , cilt.42, sa.4, ss.1942-1958, 2022 (SCI-Expanded)
2022
2022Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through computational investigations
Rudrapal M., ÇELİK İ., Khan J., Ansari M. A., Alomary M. N., Yadav R., et al.
Journal of King Saud University - Science , cilt.34, sa.3, 2022 (SCI-Expanded)
2022
2022A computational comparative analysis of the binding mechanism of molnupiravir's active metabolite to RNA-dependent RNA polymerase of wild-type and Delta subvariant AY.4 of SARS-CoV-2
ÇELİK İ., Tallei T. E.
JOURNAL OF CELLULAR BIOCHEMISTRY , cilt.123, sa.4, ss.807-818, 2022 (SCI-Expanded)
2022
2022Synthesis, Molecular Docking, and DFT Studies of Some New 2,5-Disubstituted Benzoxazoles as Potential Antimicrobial and Cytotoxic Agents
EROL M., ÇELİK İ., UZUNHİSARCIKLI E., Kuyucuklu G.
POLYCYCLIC AROMATIC COMPOUNDS , cilt.42, sa.4, ss.1679-1696, 2022 (SCI-Expanded)
2022
2022Synthesis, molecular modeling, quantum mechanical calculations and ADME estimation studies of benzimidazole-oxadiazole derivatives as potent antifungal agents
Çevik U. A., ÇELİK İ., Işık A., Pillai R. R., Tallei T. E., Yadav R., et al.
Journal of Molecular Structure , cilt.1252, 2022 (SCI-Expanded)
2022
2022Synthesis and molecular modelling of thiadizole based hydrazone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitory activities.
Işık A., Acar Çevik U., Karayel A., Celik İ., Erçetin T., Koçak A., et al.
SAR and QSAR in environmental research , cilt.33, ss.193-214, 2022 (SCI-Expanded)
2022
2022In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase
ÇELİK İ., EROL M., Duzgun Z.
MOLECULAR DIVERSITY , cilt.26, sa.1, ss.279-292, 2022 (SCI-Expanded)
2022
2022Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin
Mellado M., González C., Mella J., Aguilar L. F., ÇELİK İ., Borges F., et al.
Molecules , cilt.27, sa.3, 2022 (SCI-Expanded)
2022
2022Evaluation of Activity of Some 2,5-Disubstituted Benzoxazole Derivatives against Acetylcholinesterase, Butyrylcholinesterase and Tyrosinase: ADME Prediction, DFT and Comparative Molecular Docking Studies
ÇELİK İ., EROL M., Temiz Arpaci O., ŞENOL DENİZ F. S., ERDOĞAN ORHAN İ.
POLYCYCLIC AROMATIC COMPOUNDS , cilt.42, sa.2, ss.412-423, 2022 (SCI-Expanded)
2022
2022Synthesis, molecular docking, in silico ADME, and EGFR kinase inhibitor activity studies of some new benzimidazole derivatives bearing thiosemicarbazide, triazole, and thiadiazole
ÇELİK İ., Ayhan-Kilcigil G., Karayel A., GÜVEN B., Onay-Besikci A.
JOURNAL OF HETEROCYCLIC CHEMISTRY , cilt.59, sa.2, ss.371-387, 2022 (SCI-Expanded)
2022
2022Design, Synthesis, Molecular Docking, Molecular Dynamics and In Vivo Antimalarial Activity of New Dipeptide-Sulfonamides
Ezugwu J. A., Okoro U. C., Ezeokonkwo M. A., Hariprasad K. S., Rudrapal M., Ugwu D., et al.
CHEMISTRYSELECT , cilt.7, sa.5, 2022 (SCI-Expanded)
2022
2022Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics
Lorca M., Faúndez M., Pessoa-Mahana D., Recabarren-Gajardo G., Diethelm-Varela B., Millán D., et al.
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY , cilt.88, sa.00, ss.25-39, 2022 (SCI-Expanded)
2022
2022A comprehensive exploration of pharmacological properties, bioactivities and inhibitory potentiality of luteolin from <i>Tridax procumbens</i> as anticancer drug by in-silico approach.
Lakhera S., Rana M., Devlal K., ÇELİK İ., Yadav R.
Structural chemistry , cilt.33, sa.3, ss.703-719, 2022 (SCI-Expanded)
2022
2022Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach
Tallei T. E., Fatimawali F., Adam A. A., Elseehy M. M., El-Shehawi A. M., Mahmoud E. A., et al.
Molecules , cilt.27, sa.1, 2022 (SCI-Expanded)
2022
2022Integrated in silico - in vitro strategy for the discovery of potential xanthine oxidase inhibitors from Egyptian propolis and their synergistic effect with allopurinol and febuxostat
Ghallab D. S., Shawky E., Metwally A. M., ÇELİK İ., Ibrahim R. S., Mohyeldin M. M.
RSC ADVANCES , cilt.12, sa.5, ss.2843-2872, 2022 (SCI-Expanded)
2022
2022Investigation of reactive properties, adsorption on fullerene, DFT, molecular dynamics simulation of an anthracene derivative targeting dihydrofolate reductase and human dUTPase
Mary Y. S., Mary Y. S., Armakovic S., Armakovic S. J., Yadav R., ÇELİK İ., et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.40, sa.21, ss.10952-10961, 2022 (SCI-Expanded)
2021
2021Antidiabetic bioactive compounds from Tetrastigma angustifolia (Roxb.) Deb and Oxalis debilis Kunth.: Validation of ethnomedicinal claim by in vitro and in silico studies
Junejo J. A., Zaman K., Rudrapal M., ÇELİK İ., Attah E. I.
SOUTH AFRICAN JOURNAL OF BOTANY , cilt.143, ss.164-175, 2021 (SCI-Expanded)
2021
2021Appraisal of bioactive compounds of betel fruit as antimalarial agents by targeting plasmepsin 1 and 2: A computational approach
Fatimawali F., Tallei T. E., Kepel B. J., Alorabi M., El-Shehawi A. M., Bodhi W., et al.
Pharmaceuticals , cilt.14, sa.12, 2021 (SCI-Expanded)
2021
2021Synthesis, quantum mechanical calculations, antimicrobial activities and molecular docking studies of five novel 2,5-disubstituted benzoxazole derivatives
Temiz-Arpaci O., Zeyrek C. T., Arisoy M., EROL M., Celik I., Kaynak-Onurdag F.
JOURNAL OF MOLECULAR STRUCTURE , cilt.1245, 2021 (SCI-Expanded)
2021
2021Synthesis, NMR, X-ray crystallography and DFT studies of some regioisomers possessing imidazole heterocycles
PÜSKÜLLÜ M. O., Doganc F., Ozden S., ŞAHİN E., ÇELİK İ., Goker H.
Journal of Molecular Structure , cilt.1243, 2021 (SCI-Expanded)
2021
2021Molecular docking, DFT analysis, and dynamics simulation of natural bioactive compounds targeting ACE2 and TMPRSS2 dual binding sites of spike protein of SARS CoV-2
Yadav R., Hasan S., Mahato S., ÇELİK İ., Mary Y., Kumar A., et al.
Journal of Molecular Liquids , cilt.342, 2021 (SCI-Expanded)
2021
2021In silico and in vitro evaluation of the antimicrobial potential of bacillus cereus isolated from apis dorsata gut against neisseria gonorrhoeae
Niode N. J., Adji A., Rimbing J., Tulung M., Alorabi M., El-Shehawi A. M., et al.
Antibiotics , cilt.10, sa.11, 2021 (SCI-Expanded)
2021
2021In Silico Evaluation of Iranian Medicinal Plant Phytoconstituents as Inhibitors against Main Protease and the Receptor-Binding Domain of SARS-CoV-2
Mousavi S. S., Karami A., Haghighi T. M., Tumilaar S. G., Fatimawali F., Idroes R., et al.
MOLECULES , cilt.26, sa.18, 2021 (SCI-Expanded)
2021
2021Interactions of the receptor binding domain of sars-cov-2 variants with hace2: Insights from molecular docking analysis and molecular dynamic simulation
ÇELİK İ., Yadav R., Duzgun Z., Albogami S., El-Shehawi A. M., Fatimawali F., et al.
Biology , cilt.10, sa.9, 2021 (SCI-Expanded)
2021
2021Approach to the mechanism of action of hydroxychloroquine on SARS-CoV-2: a molecular docking study
Celik K., Onay-Besikci A., Ayhan-Kilcigil G.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.39, sa.15, ss.5792-5798, 2021 (SCI-Expanded)
2021
2021An Analysis Based on Molecular Docking and Molecular Dynamics Simulation Study of Bromelain as Anti-SARS-CoV-2 Variants
Tallei T. E., Fatimawali F., Yelnetty A., Idroes R., Kusumawaty D., Emran T. B., et al.
Frontiers in Pharmacology , cilt.12, 2021 (SCI-Expanded)
2021
2021Stability and reactivity study of bio-molecules brucine and colchicine towards electrophile and nucleophile attacks: Insight from DFT and MD simulations
Mary Y. S., Mary Y. S., Armaković S., Armaković S. J., Yadav R., ÇELİK İ., et al.
Journal of Molecular Liquids , cilt.335, 2021 (SCI-Expanded)
2021
2021DFT, docking, MD simulation, and vibrational spectra with SERS analysis of a benzoxazole derivative: an anti-cancerous drug
Sheena Mary Y., Shyma Mary Y., Temiz-Arpaci O., Yadav R., ÇELİK İ.
CHEMICAL PAPERS , cilt.75, sa.8, ss.4269-4284, 2021 (SCI-Expanded)
2021
2021Molecular modeling, density functional theory, ADME prediction and antimicrobial activity studies of 2-(substituted)oxazolo[4,5-b]pyridine derivatives
ÇELİK İ., EROL M., Kuyucuklu G.
NEW JOURNAL OF CHEMISTRY , cilt.45, sa.25, ss.11108-11118, 2021 (SCI-Expanded)
2021
2021Synthesis, Molecular Docking, Molecular Dynamics, DFT and Antimicrobial Activity Studies of 5-substituted-2-(p-methylphenyl)benzoxazole Derivatives
EROL M., ÇELİK İ., Kuyucuklu G.
JOURNAL OF MOLECULAR STRUCTURE , cilt.1234, 2021 (SCI-Expanded)
2021
2021Design, synthesis, molecular docking, density functional theory and antimicrobial studies of some novel benzoxazole derivatives as structural bioisosteres of nucleotides
EROL M., ÇELİK İ., Temiz-Arpaci O., Kaynak-Onurdag F., Okten S.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.39, sa.9, ss.3080-3091, 2021 (SCI-Expanded)
2021
2021Modeling the structural and reactivity properties of hydrazono methyl-4H-chromen-4-one derivatives-wavefunction-dependent properties, molecular docking, and dynamics simulation studies.
Mary Y. S., Mary Y. S., Resmi K. S., Sarala S., Yadav R., Celik İ.
Journal of molecular modeling , cilt.27, ss.186, 2021 (SCI-Expanded)
2021
2021Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles.
Doganc F., Celik İ., Eren G., Kaiser M., Brun R., Goker H.
European journal of medicinal chemistry , cilt.221, ss.113545, 2021 (SCI-Expanded)
2021
2021Theoretical investigation on the reactive and interaction properties of sorafenib – DFT, AIM, spectroscopic and Hirshfeld analysis, docking and dynamics simulation
Mary Y. S., Mary Y. S., Rad A. S., Yadav R., ÇELİK İ., Sarala S.
Journal of Molecular Liquids , cilt.330, 2021 (SCI-Expanded)
2021
2021Investigation of reactive properties of an antiviral azatricyclo derivative–KDFT, MD and docking simulations
Mary Y. S., Mary Y. S., Armaković S., Armaković S. J., Pakosinska-Parys M., Yadav R., et al.
Journal of Molecular Structure , cilt.1230, 2021 (SCI-Expanded)
2021
2021A Comprehensive Review of the Potential Use of Green Tea Polyphenols in the Management of COVID-19
Tallei T. E., Fatimawali F., Niode N. J., Idroes R., Zidan B. M. R. M., Mitra S., et al.
Evidence-based Complementary and Alternative Medicine , cilt.2021, 2021 (SCI-Expanded)
2020
20201H-Benzimidazole-5-carboxamidine derivatives: design, synthesis, molecular docking, DFT and antimicrobial studies
EROL M., ÇELİK İ., Temiz-Arpaci O., Goker H., Kaynak-Onurdag F., Okten S.
NEW JOURNAL OF CHEMISTRY , cilt.44, sa.48, ss.21309-21317, 2020 (SCI-Expanded)
2020
2020Synthesis, molecular docking and ADME prediction of some new benzimidazole carboxamidines derivatives as antimicrobial agents
EROL M., ÇELİK İ., Temiz-Arpaci O., Goker H., Kaynak-Onurdag F., Okten S.
MEDICINAL CHEMISTRY RESEARCH , cilt.29, sa.11, ss.2028-2038, 2020 (SCI-Expanded)
2020
2020Antimicrobial and antiproliferative activity studies of some new quinoline-3-carbaldehyde hydrazone derivatives
PÜSKÜLLÜ M. O., ÇELİK İ., EROL M., FATULLAYEV H., UZUNHİSARCIKLI E., Kuyucuklu G.
Bioorganic Chemistry , cilt.101, 2020 (SCI-Expanded)
2019
2019Design, synthesis and docking studies of benzimidazole derivatives as potential EGFR inhibitors
Celik İ., Ayhan-Kılcıgil G., Guven B., Kara Z., Gurkan-Alp A. S., Karayel A., et al.
European Journal of Medicinal Chemistry , cilt.173, ss.240-249, 2019 (SCI-Expanded)
Diğer Dergilerde Yayınlanan Makaleler
2024
2024Unveiling the immunomodulatory mechanisms of pineapple metabolites: A multi-modal computational analysis using network pharmacology, molecular docking, and molecular dynamics simulation
Tallei T., Fatimawali F., Yelnetty A., Niode N., Kusumawaty D., Idroes R., et al.
Journal of Advanced Biotechnology and Experimental Therapeutics , cilt.7, sa.1, ss.1-22, 2024 (Hakemli Dergi)
2023
2023A computational simulation appraisal of banana lectin as a potential anti-SARS-CoV-2 candidate by targeting the receptor-binding domain.
Hessel S. S., Dwivany F. M., Zainuddin I. M., Wikantika K., Celik İ., Emran T. B., et al.
Journal, genetic engineering & biotechnology , cilt.21, sa.1, ss.148, 2023 (ESCI)
2023
20234’-fluorouridine as a potential COVID-19 oral drug?: a review
Abas A. H., Tallei T. E., Fatimawali F., Çelik İ., Alhumaydhi F. A., Emran T. B., et al.
F1000 RESEARCH , cilt.11, sa.410, ss.1-20, 2023 (Scopus)
2023
2023Design, docking, MD simulation and in-silco ADMET prediction studies of novel indolebased benzamides targeting estrogen receptor alfa positive for effective breast cancer therapy
Warude B. J., Wagh S. N., Chatpalliwar V. A., YILDIRIM M., ÇELİK İ., Rudrapal M., et al.
Pharmacia , cilt.70, sa.2, ss.307-316, 2023 (ESCI)
2022
2022SARS-CoV-2 Infection may be Prevented with Cytochrome Inhibitors: Cobicistat and Ritonavir
Çelik İ., Gülten E., Beşikci A., Çınar G., Akdemir Kalkan İ., Kılcıgil G., et al.
Infectious diseases and clinical microbiology (Online) , cilt.2022, sa.4, ss.185-191, 2022 (ESCI)
2022
20224'-fluorouridine and its derivatives as potential COVID-19 oral drugs: a review
Abas A. H., Tallei T. E., Fatimawali F., ÇELİK İ., Alhumaydhi F. A., Emran T. B., et al.
F1000Research , cilt.11, 2022 (Scopus)
2022
2022VIRTUAL SCREENING AND MOLECULAR DOCKING ANALYSIS ON THREE SARS-COV-2 DRUG TARGETS BY MULTIPLE COMPUTATIONAL APPROACH ÇOKLU HESAPLAMALI YAKLAŞIMLA ÜÇ SARS-COV-2 İLAÇ HEDEFLERİ ÜZERİNDE SANAL TARAMA VE MOLEKÜLER DOKİNG ANALİZİ
ÇELİK İ., EROL M., UZUNHİSARCIKLI E., İNCE U.
Ankara Universitesi Eczacilik Fakultesi Dergisi , cilt.46, sa.2, ss.376-392, 2022 (Scopus)
2021
2021Synthesis, molecular docking, in silico ADME and antimicrobial activity studies of some new benzimidazole-triazole derivatives
Evren A. E., Çelik İ., Çevik U. A.
Cumhuriyet Science Journal , cilt.42, sa.4, ss.795-805, 2021 (Hakemli Dergi)
2021
2021Bazı Yeni 2,5-Disübstitüe Benzoksazol Türevlerinin Sentezi, Antimikrobiyal Aktivite, Moleküler Doking ve DFT Çalışmaları
Erol M., Çelik İ., Kuyucuklu G.
Avrupa Bilim ve Teknoloji Dergisi , sa.27, ss.605-614, 2021 (Hakemli Dergi)
2021
2021Molecular docking and dynamics simulations study of selected phytoconstituents of “pangi” (Pangium edule reinw) leaf as anti-sars-cov-2
Sailah I., Tumilaar S. G., Lombogia L. T., ÇELİK İ., Tallei T. E.
Philippine Journal of Science , cilt.150, sa.5, ss.925-937, 2021 (Scopus)
2021
20212-(p-Florofenil)-5-(2-(4-asetilpiperazin-1-il)asetamido)benzoksazol’ün Sentezi, Moleküler Doking, DFT ve Antimikrobiyal Aktivite Çalışmaları
Erol M., Çelik İ., Kuyucuklu G.
Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi , cilt.11, sa.3, ss.2122-2132, 2021 (Hakemli Dergi)
2021
2021MD, DFT Investigations and Inhibition of the Novel SARS- CoV-2 Mainprotease in Three Cocrystals of Hydrochloro- thiazide
Mary Y. S., Mary Y. S., Yadav R., Çelik İ., Rad A. S.
Analytical Chemistry Letters , cilt.11, sa.4, ss.450-468, 2021 (Hakemli Dergi)
2021
2021Bioactive antidiabetic flavonoids from the stem bark of cordia dichotoma forst.: Identification, docking and ADMET studies
Hussain N., Kakoti B. B., Rudrapal M., Sarwa K. K., ÇELİK İ., Attah E. I., et al.
MolBank , cilt.2021, sa.2, 2021 (ESCI)
2021
2021Synthesis, Antimicrobial and Cytotoxic Activity Studies of Some New Benzoxazole Derivatives
Erol M., Çelik İ., Kuyucuklu G., Uzunhisarcıklı E.
Avrupa Bilim ve Teknoloji Dergisi , cilt.21, ss.455-462, 2021 (Hakemli Dergi)
2021
2021Synthesis, antimicrobial and in silico studies of new 2,5-disubstituted benzoxazole derivative
Erol M., Çelik İ., Kuyucuklu G.
Medicine Science , cilt.10, sa.2, ss.400-408, 2021 (Hakemli Dergi)
Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar
2022
2022SARS-CoV-2’NİN OMİKRON VE DELTA VARYANTLARININ BULAŞ HIZININ BİLGİSAYAR SİMÜLAYONLARI İLE ANALİZİ
ÇELİK İ.
4. INTERNATIONAL SCIENCES AND INNOVATION CONGRESS, Ankara, Türkiye, 19 Şubat 2022
2021
2021MOLNUPİRAVİR AKTİF METABOLİTİNİN SARS-CoV2'NİN RNA'YA BAĞIMLI RNA POLİMERAZINA KARŞI POTANSİYEL İNHİBİTÖR AKTİVİTESİNİN İN SİLİKO DEĞERLENDİRİLMESİ
ÇELİK İ.
Gevher Nesibe 8. Uluslararası Sağlık Bilimleri Kongresi, İstanbul, Türkiye, 19 Kasım 2021
2019
2019SYNTHESIS, MOLECULAR DOCKING AND EGFR KINASE INHIBITORY ACTIVITY STUDIES OF BENZIMIDAZOLE DERIVATIVES BEARING PROPYL-LINKED TO OXADIAZOLE RING
ÇELİK İ., KILCIGİL G., KARA Z., GÜVEN B., BEŞİKCİ A.
EFMC-YMCS 2019 6th EFMC Young Medicinal Chemists' Symposium, Atina, Yunanistan, 05 Eylül 2019
2018
2018SYNTHESIS OF SOME CYCLOHEXYL SUBSTITUTED OXADIAZOLE DERIVATIVES LINKED 1H-BENZIMIDAZOLE
Çelik I., Kılcıgil G.
International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Türkiye, 26 Haziran 2018 - 29 Mayıs 2019, ss.384-385
2018
2018Molecular Docking Studies of Some Novel Benzimidazole Derivatives as EGFR Inhibitors
Alp A. S., Çelik I., Kılcıgil G.
International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Türkiye, 26 Haziran 2018 - 29 Mayıs 2019, ss.400
2018
2018SYNTHESIS OF SOME 1H-BENZIMIDAZOLE COMPOUNDS BEARING BIS-THIOSEMICARBAZIDE AND TRIAZOLE DERIVATIVES AS INHIBITORS OF EGFR TYROSINE KINASE
Çelik I., Kılcıgil G., Güven B., Kara Z., Beşikci A.
International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Türkiye, 26 - 29 Haziran 2018, ss.384
2017
2017SYNTHESIS OF SOME 1H-BENZIMIDAZOLES CONTAINING CYCLOHEXYL SUBSTITUTED THIOSEMICARBAZIDES, TRIAZOLES, THIADIAZOLES AS INHIBITORS OF EGFR TYROSINE KINASE
ÇELİK İ., KILCIGİL G., Kara Z., GÜVEN B., BEŞİKCİ A.
GPSS2017, 11 - 13 Ekim 2017
2017
2017SYNTHESIS OF SOME THIADIAZOLE/TRIAZOLE LINKED 1H-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF EGFR TYROSINE KINASE
Çelik I., Kılcıgil G., Kara Z., Güven B., Beşikci A.
2nd International Gazi Pharma Symposium Series (GPSS-2017), Ankara, Türkiye, 11 - 13 Ekim 2017, ss.249
2016
2016Synthesis of Some 1H-Benzimidazoles as Inhibitors of EGFR Tyrosine Kinase
Çelik I., Kılcıgil G., Beşikci A.
ICPC 2016 : International Conference on Physical Chemistry, Kobenhavn, Danimarka, 27 - 28 Haziran 2016, cilt.10, sa.6
2014
2014Chrysophthalmum gueneri bitkisinin A 549 ve Hep G2 hücreleri üzerine sitotoksik etkileri
Çelik İ., Dokumacı A. H., Akşit A., Gürbüz P., Aycan M. B.
5. Multidisipliner Kanser Araştırma Kongresi, Muğla, Türkiye, 25 - 27 Nisan 2014, ss.177
2014
2014The cytotoxic effects of Chrysophthalmum dichotomum on A549 and HepG2 cell lines
AYCAN M. B., DOKUMACI A. H., AKŞİT A., ÇELİK İ., GÜRBÜZ P.
2nd Anticancer Agents Congress, Muğla, Türkiye, 23 - 25 Nisan 2014
2014
2014The cytotoxic effects of Crystaphalmum dichotomum on A549 and HepG2 cell lines
AYCAN M. B., DOKUMACI A. H., Akşit A., Çelik İ., GÜRBÜZ P.
2nd Anticancer Agent Congress, Muğla, Türkiye, 23 - 25 Nisan 2014, ss.62
Kitap & Kitap Bölümleri
2020
2020TARGETING EGFR L858R1T790M AND EGFR L858R1T790M/C797S RESISTANCE MUTATIONS IN NON-SMALL CELL LUNG CANCER: CURRENT APPROACHES IN MEDICINAL CHEMISTRY
Çelik İ., Kılcıgil G.
Eczacılıkta Yenilikler-3, Gülbin Özçelikay,İlkay Yıldız, Editör, Ankara Üniversitesi, Ankara, ss.249-264, 2020
Desteklenen Projeler
2020 - Devam Ediyor
2020 - Devam EdiyorBENZOKSAZOL YAPISI TASIYAN BAZI YENI BILESIKLERIN TASARIMI, MOLEKÜLER DOCKING ÇALISMASI, SENTEZI ILE EGFR ve VEGFR-2 KINAZ AKTIVITELERI ÜZERINE ETKILERININ DEGERLENDIRILMESI
TÜBİTAK Projesi
EROL M.(Yürütücü), PÜSKÜLLÜ M. O., ÇELİK İ., DEMİRPOLAT E., ARPACI Ö.
2020 - 2022
2020 - 2022Virtual Screening ve Moleküler Docking Çalışmaları ile Doğal Yapılı Bileşiklerin Tespiti ve in vitro Alzheimer Modelinde Tau Düzeyi Üzerine Etkilerinin Değerlendirilmesi
Yükseköğretim Kurumları Destekli Proje
Uzunhisarcıklı E. (Yürütücü), Çelik İ., Aycan M. B.
2020 - 2021
2020 - 2021Bazı Yeni 2,5-Disübstitüe Benzoksazol Türevi Bileşiklerin Sentezi Yapılarının Aydınlatılması ve MCF-7 Hücre Hattında İn Vitro Sitotoksik Etkisinin İncelenmesi
Yükseköğretim Kurumları Destekli Proje
Erol M. (Yürütücü), Çelik İ., Uzunhisarcıklı E.
2020 - 2021
2020 - 2021Benzoksazol Yapısı Taşıyan Bazı Yeni Bileşiklerin Tasarımı, Moleküler Docking Çalışması, Sentezi İle EGFR ve VEGFR-2 Kinaz Aktiviteleri Üzerine Etkilerinin Değerlendirilmesi
TÜBİTAK Projesi
Erol M. (Yürütücü), Arpacı Ö., Püsküllü M. O., Demirpolat E., Çelik İ.
2019 - 2020
2019 - 2020Yeni Bazı Kinolin 3-Karbaldehit Hidrazon Türevlerinin Sentezi Yapılarının Aydınlatılması Antimikrobiyal Etkilerinin Değerlendirilmesi ve Moleküler Docking Çalışmaları
Yükseköğretim Kurumları Destekli Proje
Püsküllü M. O. (Yürütücü), Erol M., Çelik İ., Fatullayev H.
2019 - 2020
2019 - 2020Bazı Yeni Benzoksazol Türevi Bileşiklerin Sentezi, Moleküler Docking Çalışmaları ve Antimikrobiyal Etkilerinin Değerlendirilmesi
Yükseköğretim Kurumları Destekli Proje
Erol M. (Yürütücü), Arpacı Ö., Püsküllü M. O., Çelik İ., Fatullayev H., Hızlısoy H.
2019 - 2019
2019 - 2019Yeni Bazı Kinolin 3-Karbaldehit Hidrazon Türevlerinin Sentezi
Yükseköğretim Kurumları Destekli Proje
PÜSKÜLLÜ M. O. (Yürütücü), ÇELİK I., FATULLAYEV H.
2019 - 2019
2019 - 2019Bazı Yeni 2-Merkapto Pirimidin Türevlerinin Sentezi
Yükseköğretim Kurumları Destekli Proje
EROL M. (Yürütücü), ÇELİK I., FATULLAYEV H.
Bilimsel Hakemlikler
Haziran 2021
Haziran 2021COMPUTERS IN BIOLOGY AND MEDICINE
SCI Kapsamındaki Dergi
Şubat 2021
Şubat 2021JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
SCI Kapsamındaki Dergi
Kongre ve Sempozyum Katılımı Faaliyetleri
01 Ekim 2017 - 01 Ekim 2017
01 Ekim 2017 - 01 Ekim 20172nd International Gazi Pharma Symposium Series (GPSS-2017)
Katılımcı
Ankara-Türkiye
01 Haziran 2016 - 01 Haziran 2016
01 Haziran 2016 - 01 Haziran 2016XII. Türk Eczacılık Tarihi Toplantısı
Katılımcı
Eskişehir-Türkiye
Burslar
2016 - 2018
2016 - 2018