Bioaccessibility of Cr, Cu, Fe, Mg, Mn, Mo, Se and Zn from nutritional supplements by the unified BARGE method

Tokalıoğlu Ş. , Clough R., Foulkes M., Worsfold P.

FOOD CHEMISTRY, vol.150, pp.321-327, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 150
  • Publication Date: 2014
  • Doi Number: 10.1016/j.foodchem.2013.10.151
  • Title of Journal : FOOD CHEMISTRY
  • Page Numbers: pp.321-327


In this study, the Unified Bioaccessibility Research Group of Europe (BARGE) in vitro method was used to assess the bioaccessibility of Cr, Cu, Fe, Mg, Mn, Mo, Se, and Zn in ten nutritional supplement samples and three certified reference materials. The total digest, gastric phase and gastro-intestinal phase concentrations of Cu, Fe, Mg, Mn and Zn were determined by ICP-OES and Cr, Mo and Se by ICP-MS. The bioaccessible fractions of the elements in the gastric phase for the nutritional supplements were in the range 13-89% for Cr, 9-79% for Cu, 55-99% for Fe, 33-95% for Mg, 83-94% for Mn, 42-101% for Mo, 74-125% for Se and 81-104% for Zn. The range for the gastrointestinal phase was 6-65% for Cr, 27-66% for Cu, 3-14% for Fe, 34-91% for Mg, 53-62% for Mn, 40-109% for Mo, 53-146% for Se and 3-35% for Zn. (C) 2013 Elsevier Ltd. All rights reserved.