Computer-Aided Drug Design and Synthesis Research Group

Welcome to CADDS Research Group!
Established on February 23, 2025, at Erciyes University Faculty of Pharmacy, the Computer-Aided Drug Design and Synthesis Research Group (CADDS) warmly welcomes you! We are thrilled to invite you to join us on our journey to develop innovative drug solutions targeting protein tyrosine kinases. We extend an open invitation to everyone who shares our scientific curiosity and passion for collaboration.

At CADDS, we combine the power of medicinal chemistry and computational technologies to create impactful solutions for challenging diseases like cancer. We warmly invite you to collaborate with us in this exciting mission! Whether you bring expertise in molecular modeling, drug synthesis, or biological testing, or wish to inspire us with new ideas and projects, our doors are always open.

Let’s push the boundaries of science together and contribute to human health. As the CADDS family, we eagerly await you with open arms! Feel free to reach out for more information or collaboration opportunities.

Stronger together, forward together!
The CADDS Research Group Team

Computer-Aided Drug Design and Synthesis Research Group

Recent Publications

Design, synthesis, and biological evaluation of novel amidoxime or amidine analogues of some 4-anilino-6,7-dimethoxyquinazolines with a potent EGFR inhibitory effect.

Novel triazoloquinazoline derivatives as VEGFR inhibitors: synthesis, cytotoxic evaluation and <i>in silico</i> studies

Novel Benzimidazole-Oxadiazole Derivatives as Anticancer Agents with VEGFR2 Inhibitory Activity: Design, Synthesis, In Vitro Anticancer Evaluation, and In Silico Studies

Design, Synthesis, and Biological Evaluation of BODIPY-Caged Resiquimod as a Dual-Acting Phototherapeutic.

Molecular mechanisms of phytoconstituents from selected Egyptian plants against non-small cell lung cancer using integrated in vitro network pharmacology and molecular docking approach

Probing the Molecular Mechanisms of Kratom's Antipsychotic Effects through a Multi-modal Computational Approach.

UPLC-MS/MS based metabolomic insights into antidiabetic potential of Astragalus: Deciphering species-specific bioactive metabolites in correlation to α-amylase and α-glucosidase inhibitory activities

Investigation of the molecular interaction between apraclonidine, an α2-adrenergic receptor agonist, and bovine serum albumin using fluorescence and molecular docking techniques

In vitro and in silico guided identification of antimalarial phytoconstituent(s) in the root of Citrus maxima (Burm.) Merr.