Pentraxin 3 as a novel bio-marker of inflammation and endothelial dysfunction in autosomal dominant polycystic kidney disease


Kocyigit I. , EROĞLU E. , Orscelik O. , ÜNAL A. , Gungor O., Ozturk F. , et al.

JOURNAL OF NEPHROLOGY, cilt.27, ss.181-186, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s40620-014-0045-4
  • Dergi Adı: JOURNAL OF NEPHROLOGY
  • Sayfa Sayısı: ss.181-186

Özet

Cardiovascular disease (CVD) is the main cause of mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Prior to hypertension early vascular changes and inflammation have been reported. We aimed to investigate long pentraxin 3 (PTX-3), which has been recently described as a biomarker of inflammation, and its relation with endothelial dysfunction in early ADPKD patients.