Pentraxin 3 as a novel bio-marker of inflammation and endothelial dysfunction in autosomal dominant polycystic kidney disease

Kocyigit I., Eroğlu E., Orscelik O., Ünal A., Gungor O., Ozturk F., ...Daha Fazla

JOURNAL OF NEPHROLOGY, cilt.27, sa.2, ss.181-186, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s40620-014-0045-4
  • Dergi Adı: JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.181-186
  • Anahtar Kelimeler: Polycystic kidney disease, Pentraxin-3, Endothelial dysfunction, CORONARY-HEART-DISEASE, C-REACTIVE PROTEIN, CARDIOVASCULAR-DISEASE, HEMODIALYSIS-PATIENTS, RENAL-FUNCTION, ASSOCIATIONS, RESISTANCE, MORTALITY, RISK, PTX3
  • Erciyes Üniversitesi Adresli: Evet

Özet

Cardiovascular disease (CVD) is the main cause of mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Prior to hypertension early vascular changes and inflammation have been reported. We aimed to investigate long pentraxin 3 (PTX-3), which has been recently described as a biomarker of inflammation, and its relation with endothelial dysfunction in early ADPKD patients.