Pentraxin 3 as a novel bio-marker of inflammation and endothelial dysfunction in autosomal dominant polycystic kidney disease


Kocyigit I. , EROĞLU E. , Orscelik O. , ÜNAL A. , Gungor O., Ozturk F. , ...More

JOURNAL OF NEPHROLOGY, vol.27, no.2, pp.181-186, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.1007/s40620-014-0045-4
  • Title of Journal : JOURNAL OF NEPHROLOGY
  • Page Numbers: pp.181-186

Abstract

Cardiovascular disease (CVD) is the main cause of mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Prior to hypertension early vascular changes and inflammation have been reported. We aimed to investigate long pentraxin 3 (PTX-3), which has been recently described as a biomarker of inflammation, and its relation with endothelial dysfunction in early ADPKD patients.