The ototoxic effect of intratympanic terbinafine applied in the middle ear of rats

Sagit, Mustafa; Somdas, MEHMET; KORKMAZ, Ferhat; AKCADAG, Alper

doi:10.1186/1916-0216-42-13

The ototoxic effect of intratympanic terbinafine applied in the middle ear of rats

Atıf İçin Kopyala

Sagit M., Somdas M. A., KORKMAZ F., AKCADAG A.

JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, cilt.42, 2013 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 42
Basım Tarihi: 2013
Doi Numarası: 10.1186/1916-0216-42-13
Dergi Adı: JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
Erciyes Üniversitesi Adresli: Evet

Özet

Background: Otomycosis is defined as an infection of the external ear canal with fungal agents. The treatment of the disease is cleansing and drying of the external ear canal, identification and treatment of any predisposing factors and application of topical antifungal agents. Terbinafine is used as an antifungal agent to treat otomycosis. We proposed to investigate the probable ototoxic effect of terbinafine solution on auditory brain stem response (ABR) and distortion product otoacoustic emission (DPOAE) when applied intratympanically in the middle ear of rats.