Acute Respiratory Distress due to Antipsychotic Drugs

YAGMUR F., Ulusoy H. B., BUYUKOGLAN H., KAYA M.

PHARMACOPSYCHIATRY, vol.43, no.3, pp.118-119, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1055/s-0029-1242822
  • Journal Name: PHARMACOPSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.118-119
  • Erciyes University Affiliated: Yes

Abstract

We report a 36-year-old male schizophrenic patient who was treated with risperidone for a long time. Because of an acute psychotic reaction, haloperidol, chlorpromazine and olanzapine were administered additionally. After administration of these drugs, he developed acute respiratory distress that caused his death. We discuss the cause of this respiratory distress and conclude that it might be due to acute laryngeal dystonia caused by these antipsychotic drugs. Antipsychotic drug-induced laryngeal dystonia is rarely reported but it is a life threatening side effect. All physicians dealing with antipsychotic drug therapy must be aware of acute laryngeal dystonia, and an antiparkinsonian agent should be administered immediately.