Thrombotic Thrombocytopenic Purpura Associated With Malignancy: Report of two cases

Sari I., Yuksel O. C., ÖZKAN M., Eser B., Unal A., Sav T., ...More

ERCIYES MEDICAL JOURNAL, vol.27, no.4, pp.180-183, 2005 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 4
  • Publication Date: 2005
  • Journal Name: ERCIYES MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.180-183
  • Keywords: Malignancy, thrombotic thrombocytopenic purpura, plasma exchange
  • Erciyes University Affiliated: Yes

Abstract

Microangiopathic hemolytic anemia (MAHA) is a late hut fatal complication in advanced cancers. In this paper we report two cases presenting with a thrombotic thromhocytopenic purpura (TTP) with malignancy refractory to daily plasma exchange. The prognosis of the patients with TTP associated with malignancy are not as favorable as in the patients with classical TTP Thus, this group of patients should be treated with chemotherapy combined with supportive treatment such as plazma exchange.