Akademik Veri Yönetim Sistemi
ERCIYES MEDICAL JOURNAL, cilt.29, sa.1, ss.25-30, 2007 (ESCI)
Purpose: In this study, we aimed to evaluate renal tubular and glomerular functions Juvenile idiopathic arthritis. Material anti methods: Twenty children (12 male, 8 female) with juvenile idiopathic arthritis(JIA) and 10 children (4 boys, 6 girls) as controls were included in the study The following renal laboratory tests were performed in both patients and control group: serum biochemical parameters, electrolytes in 24-h urine, microalbumin in 24-h urine, venous pH, HCO3 and semis osmalility. The second morning urine specimens were obtained from the patients and control group in order to determine urinary Cr levels, complete urinalysis phosphorus, acetyle-beta-glucosaminidase (NAG), Renitol binding protein (RBP), renal failure index (RFI), reabsorbsion of tubular phosphorus (TRP), fractional sodium excretion (Siena), and urinary osmolality, Renal ultrasonography (USG) was undergone to determine nephrocalcinosis both patient and control group. Results: The mean follow-up duration of the patients was 21 months (range:1-107) There were no statistically significant differences with regard to glomerular and tubular functions between the patient and control groups. Renal biopsy was performed on two patients and revealed mesengioproliferative glomerulonephritis in one patient, and amyloidosis in the other. Conclusion: Our results could not determine that children with JIA tend to have renal disorders, However., this result may be linked to our limitations such as limited number of patients and the relatively short duration of the follow-up period.