The effect of amrinone on liver regeneration in experimental hepatic resection model


AKCAN A. C., KUCUK C., OK E., CANOZ O., Muhtaroglu S., YILMAZ N., ...More

JOURNAL OF SURGICAL RESEARCH, vol.130, no.1, pp.66-72, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 130 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1016/j.jss.2005.07.020
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.66-72
  • Keywords: liver, resection, regeneration, amrinone, phosphodiesterase inhibitors, CELL NUCLEAR ANTIGEN, PHOSPHODIESTERASE III INHIBITORS, ISCHEMIA-REPERFUSION INJURY, PARTIAL-HEPATECTOMY, RAT-LIVER, HEPATOCELLULAR-CARCINOMA, MILRINONE, INDEX, GRAFT
  • Erciyes University Affiliated: Yes

Abstract

Background. The phosphodiesterase inhibitors (PDEIs) have been proposed to improve hepatic reperfusion injury and hepatosplanchnic circulation, but the effects of these agents on liver regeneration have not been investigated thoroughly. The aim of this study was to investigate the effect of amrinone, a PDEI, on liver regeneration in rats.