Synthesis and antimicrobial activities of novel bisacridine-1,8-dione derivatives
MEDICINAL CHEMISTRY RESEARCH, cilt.20, sa.3, ss.293-299, 2011 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 3
- Basım Tarihi: 2011
- Doi Numarası: 10.1007/s00044-010-9321-6
- Dergi Adı: MEDICINAL CHEMISTRY RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.293-299
- Anahtar Kelimeler: Bisacridine-1,8-diones, Antimicrobial activity, Antibiotics
- Erciyes Üniversitesi Adresli: Evet
Özet
A series of bisacridine-1,8-dione derivatives were synthesized by one-pot reaction of aromatic dialdehydes, dimedone or cyclohexane-1,3-dione and primer aromatic amines in acetonitrile to utilizing Amberlyst-15 as a heterogeneous catalyst. The structures of compounds were characterized by FT-IR, NMR, and elemental analysis. Antimicrobial activities of these compounds were determined by using the disc diffusion method against to these gram-positive and gram-negative bacteria and yeast. The results were compared with reference discs.