Levofloxacin-Induced Delirium: Is It a Dangerous Drug in Patients with Renal Dysfunction?

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Kocyigit I., Dortdudak S., Sipahioglu M., ÜNAL A., Yucel H. E., TOKGÖZ B., ...More

RENAL FAILURE, vol.34, no.5, pp.634-636, 2012 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 34 Issue: 5
• Publication Date: 2012
• Doi Number: 10.3109/0886022x.2012.660855
• Journal Name: RENAL FAILURE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.634-636
• Erciyes University Affiliated: Yes

Abstract

The central nervous system (CNS) toxicity of fluoroquinolones is well known but usually occurs benign. In the literature, there are a few number of severe CNS toxicity cases related to fluoroquinolones. Levofloxacin is a third-generation fluorinated quinolone antibiotic, is the active levo stereoisomer of ofloxacin, and has one of the most favorable adverse reaction profiles. We describe a case of delirium associated with levofloxacin in a 55-year-old man who was hospitalized in our medical clinic for pneumonia.