Guillain-Barre syndrome associated with Legionnella infection

AKYILDIZ B., Guemues H., Kumandas S., COSKUN A., BAYKAN A., YIKILMAZ A., ...More

JOURNAL OF TROPICAL PEDIATRICS, vol.54, no.4, pp.275-277, 2008 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1093/tropej/fmn010
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.275-277


This is the first report of Guillain-Barre syndrome (GBS) related to Legionnella pneumophilia infection. A 13-year-old boy presented with acute dysphagia and dyspnea. He lived in a rural area and had a history of drinking potable deep-hole water. The patient was intubated because of increased respiratory distress. A positive direct fluoresein antigen test confirmed L. pneumophilia infection in BAL. One week after the first admission, acute weakness was noticed including the lower extremities and was more prominent in the distal than the proximal portions. GBS was considered as the initial diagnosis. Tests for all causes known to trigger GBS were negative. Specific serology for L. pneumophilia IgG was positive. He was treated with intravenous immunoglobulins and discharged with minor weakness and difficulty in walking in the second month. On the basis of this case, L. pneumophilia should be included in the etiologic spectrum of GBS.