Evaluation of platelet parameters and neutrophil/lymphocyte ratio during omalizumab treatment in patients with severe chronic spontaneous urticaria

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Ertas R., Ozyurt K., Karakukcu Ç., Akkus M. R., Ozlu E., Avci A., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.48, sa.6, ss.1255-1262, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3906/sag-1803-87
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1255-1262
  • Anahtar Kelimeler: Chronic spontaneous urticaria, inflammation, platelet, MPV, PDW, NLR, PLR, omalizumab, NEUTROPHIL-LYMPHOCYTE RATIO, IGE LEVELS, VOLUME, MANAGEMENT, ACTIVATION, GUIDELINE, DIAGNOSIS, DISEASE
  • Erciyes Üniversitesi Adresli: Hayır

Özet

Background/aim: Spontaneous wheals and/or angioedema lasting longer than six weeks are described as chronic spontaneous urticaria (CSU). Omalizumab is used for the treatment of antihistamine-resistant CSU. The neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet distribution width (PDW) are considered important indicators of inflammation and platelet activation in chronic diseases.