Biphasic anaphylaxis to gemifloxacin


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YILMAZ İ., Dogan S., TUTAR N., Kanbay A., Buyukoglan H., Demir R.

ASIA PACIFIC ALLERGY, vol.2, no.4, pp.280-282, 2012 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 2 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.5415/apallergy.2012.2.4.280
  • Journal Name: ASIA PACIFIC ALLERGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.280-282
  • Keywords: Alpha blocker, Beta blocker, Biphasic anaphylaxis, Gemifloxacin, ACE inhibitor
  • Erciyes University Affiliated: Yes

Abstract

Anaphylaxis have been documented as adverse effects of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin, and moxifloxacin. However resistant and biphasic anaphlylactic reactions to gemifloxacin have not been reported to date. Management of severe anaphylaxis in the elderly can be complicated by concurrent medications such as beta (beta) adrenergic, alpha (alpha) adrenergic blockers and angiotensin-converting enzyme (ACE) inhibitors. We report here in the case of a 60-year-old male who was taking on ACE inhibitor, alpha and beta blockers and experienced a severe, resistant and biphasic anaphlylactic reaction to gemifloxacin mesylate.