VEGFR1 expression is related to lymph node metastasis and serum VEGF may be a marker of progression in the follow-up of patients with differentiated thyroid carcinoma

Karaca, Zahide; TANRIVERDİ, Fatih; ÜNLÜHİZARCI, KÜRŞAD; ÖZTÜRK, FİGEN; GÖKAHMETOĞLU, SELMA; Elbuken, Gülşah; Cakir, I.; BAYRAM, FAHRİ; Kelestimur, ZÜLEYHA

doi:10.1530/eje-10-0967

VEGFR1 expression is related to lymph node metastasis and serum VEGF may be a marker of progression in the follow-up of patients with differentiated thyroid carcinoma

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Karaca Z., TANRIVERDİ F., ÜNLÜHİZARCI K., ÖZTÜRK F., GÖKAHMETOĞLU S., Elbuken G., ...More

EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol.164, no.2, pp.277-284, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 164 Issue: 2
Publication Date: 2011
Doi Number: 10.1530/eje-10-0967
Journal Name: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.277-284
Erciyes University Affiliated: Yes

Abstract

Objective: Vascular endothelial growth factor (VEGF) and VEGF receptor 1 (VEGFR1) are known to be related to thyroid tumorigenesis. The aim of the study was to examine the expressions and serum levels of VEGF, VEGFR1, IGF1, and IGF1 receptor (IGF1R) in patients with differentiated thyroid carcinoma (DTC) compared with patients with nodular goiter (NG).