VEGFR1 expression is related to lymph node metastasis and serum VEGF may be a marker of progression in the follow-up of patients with differentiated thyroid carcinoma


Karaca Z. , TANRIVERDİ F. , ÜNLÜHİZARCI K. , ÖZTÜRK F. , GÖKAHMETOĞLU S. , Elbuken G. , et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY, cilt.164, ss.277-284, 2011 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 164 Konu: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1530/eje-10-0967
  • Dergi Adı: EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Sayfa Sayısı: ss.277-284

Özet

Objective: Vascular endothelial growth factor (VEGF) and VEGF receptor 1 (VEGFR1) are known to be related to thyroid tumorigenesis. The aim of the study was to examine the expressions and serum levels of VEGF, VEGFR1, IGF1, and IGF1 receptor (IGF1R) in patients with differentiated thyroid carcinoma (DTC) compared with patients with nodular goiter (NG).