VEGFR1 expression is related to lymph node metastasis and serum VEGF may be a marker of progression in the follow-up of patients with differentiated thyroid carcinoma


Karaca Z. , TANRIVERDİ F. , ÜNLÜHİZARCI K. , ÖZTÜRK F. , GÖKAHMETOĞLU S. , Elbuken G. , ...More

EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol.164, no.2, pp.277-284, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 164 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.1530/eje-10-0967
  • Title of Journal : EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Page Numbers: pp.277-284

Abstract

Objective: Vascular endothelial growth factor (VEGF) and VEGF receptor 1 (VEGFR1) are known to be related to thyroid tumorigenesis. The aim of the study was to examine the expressions and serum levels of VEGF, VEGFR1, IGF1, and IGF1 receptor (IGF1R) in patients with differentiated thyroid carcinoma (DTC) compared with patients with nodular goiter (NG).