The effects of dexmedetomidine on mesenteric arterial occlusion-associated gut ischemia and reperfusion-induced gut and kidney injury in rabbits

Kilic, Kemal; Hanci, Volkan; Selek, Sahbettin; Sozmen, Mahmut; Kilic, Nergiz; Citil, MEHMET; YURTLU, Derya; Yurtlu, B.

doi:10.1016/j.jss.2012.03.073

The effects of dexmedetomidine on mesenteric arterial occlusion-associated gut ischemia and reperfusion-induced gut and kidney injury in rabbits

Atıf İçin Kopyala

Kilic K., Hanci V., Selek S., Sozmen M., Kilic N., Citil M., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.178, sa.1, ss.223-232, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 178 Sayı: 1
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.jss.2012.03.073
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.223-232
Anahtar Kelimeler: Experimental mesenteric ischemia, Dexmedetomidine, Renal, Intestinal, Rabbit, Mesenteric artery occlusion, INTESTINAL ISCHEMIA/REPERFUSION INJURY, CRITICALLY-ILL PATIENTS, INFLAMMATORY RESPONSES, CEREBRAL-ISCHEMIA, GLOBAL-ISCHEMIA, NITRIC-OXIDE, ALPHA-2-ADRENOCEPTOR AGONIST, SUPEROXIDE-DISMUTASE, RAT-KIDNEY, MODEL
Erciyes Üniversitesi Adresli: Hayır

Özet

Objective: We assessed the antioxidant activity of dexmedetomidine (Dex) administered during the ischemic period in a rabbit model of mesenteric ischemia/reperfusion (I/R) injury using biochemical and histopathological methods.