A long survived pediatric patient with recurrent anaplastic ependymoma: A case report and review of the literature

Benderli Cihan Y., DENİZ K., DÖNMEZ H.

Turkiye Klinikleri Pediatri, vol.21, no.2, pp.96-101, 2012 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 2
  • Publication Date: 2012
  • Journal Name: Turkiye Klinikleri Pediatri
  • Journal Indexes: Scopus
  • Page Numbers: pp.96-101
  • Erciyes University Affiliated: Yes


Ependymoma is the third most common brain tumor in the childhood, following astrocytoma and medulloblastoma. Ependymoma represents 6-10% of all brain tumors in the pediatric age group. Commonly surgery is the first treatment option. Adjuvant radiotherapy and/or chemotherapy are performed according to age and clinical manifestations of the patients. The extent of tumor resection and control of local recurrence are the primary factors affecting the treatment outcome. Researches demonstrated that 80-95% of deaths are attributed to tumor progression at the primary site. A male pediatric patient suffering from multiple recurrences of ependymoma with anaplastic transformation is presented here. We suggest that the combination of surgery, adjuvant radiotherapy and chemotherapy is highly effective for controlling recurrent ependymoma. Copyright © 2012 by Türkiye Klinikleri.