Evaluation of vascular endothelial growth factor A and endostatin levels in induced sputum and relationship to bronchial hyperreactivity in patients with seasonal allergic rhinitis

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Yilmaz I., Bayraktar N., Ceyhan K., Secil D., Yuksel S., Misirligil Z., ...More

AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, vol.27, no.3, pp.181-186, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 27 Issue: 3
• Publication Date: 2013
• Doi Number: 10.2500/ajra.2013.27.3867
• Journal Name: AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.181-186
• Erciyes University Affiliated: Yes

Abstract

Background: Studies about the pathogenesis of bronchial hyperreactivity (BHR) in patients with allergic rhinitis (AR) and its relationship with lower airway remodeling are extremely limited. In this study, bronchial vascular remodeling and its relationship with BHR were evaluated by measurement of vascular endothelial growth factor A (VEGF-A) and endostatin in patients with seasonal AR (SAR).