The effects of octreotide in dilated cardiomyopathy - An open-label trial in 12 patients


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Eryol N. K. , Guven M. , Topsakal R. , Sungur M. , Ozdogru I., Inanc T., ...More

JAPANESE HEART JOURNAL, vol.45, no.4, pp.613-621, 2004 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 4
  • Publication Date: 2004
  • Doi Number: 10.1536/jhj.45.613
  • Title of Journal : JAPANESE HEART JOURNAL
  • Page Numbers: pp.613-621
  • Keywords: dilated cardiomyopathy, octreotide, CONGESTIVE-HEART-FAILURE, IGF-I AXIS, GROWTH-HORMONE, SOMATOSTATIN ANALOG, EXERCISE CAPACITY, GUINEA-PIG, IMPROVEMENT, HYPERTROPHY, MECHANISMS, THERAPY

Abstract

Octreotide, a somatostatin analogue, has been found effective in the treatment of acromegalic cardiomyopathy. We investigated whether intermittent octreotide therapy had beneficial effects in patients with ischemic or idiopathic dilated cardiomyopathy, which are refractory to conventional therapy.