Role of kallistatin in pediatric patients with pulmonary arterial hypertension


Pamukcu O. , Ay D. , ÜZÜM K. , Barlakketi D., KÖSE M. , BAYKAN A. , ...Daha Fazla

TURKISH JOURNAL OF PEDIATRICS, cilt.62, ss.405-410, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 62 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.24953/turkjped.2020.03.007
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Sayfa Sayıları: ss.405-410

Özet

Background and objectives. Kallistatin, a serine proteinase inhibitor, exerts its effect by vascular repair, angiogenesis inhibition, strong vasodilation, inhibition of vascular endothelial growth factor (VEGF), anti-inflammation, and anti-apoptosis. We hypothesized as to whether it has a protective role in pulmonary arterial hypertension (PAH).