Synthesis of some pyrazole-3-carboxylic acid-hydrazide and pyrazolopyridazine compounds

ILHAN I., Saripinar E., AKCAMUR Y.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.42, no.1, pp.117-120, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 1
  • Publication Date: 2005
  • Doi Number: 10.1002/jhet.5570420117
  • Journal Name: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.117-120
  • Erciyes University Affiliated: Yes

Abstract

Furan-2,3-diones la-c react with various hydrazines 2a-c under different conditions to yield the pyrazole-3-carboxylic acid-hydrazide 3a-d. Cyclocondensation reactions of la or 7 with phenylhydrazine lead to derivatives of pyrazolo[3,4-d]pyridazinones 6 and 8, respectively. The structures of all products were confirmed by elemental analysis, IR, H-1- and C-13-NMR spectroscopic measurements.