Akademik Veri Yönetim Sistemi
Current Research in Dental Sciences, cilt.33, sa.3, ss.174-178, 2023 (Scopus)
Periodontal diseases are chronic infectious diseases caused by microbial dental plaque local-ized on teeth. Periodontitis is very common worldwide. When not treated, it can cause alveolar bone loss and attachment loss and lead to loss of function in teeth over time, and the final pic-ture may be tooth loss. Helicobacter pylori is a spiral-shaped pathogen that can cause a wide range of diseases ranging from chronic gastric to gastric cancer, primarily colonized in the stomach and gastrointestinal system. Therefore, elimination of this potentially harmful bacterium is important. Although initially conventional systemic eradication therapy was successful, increasing antibiotic resistance and side effects decreased their success rates in the clinical setting. Additionally, increasing recurrence rates have prompted researchers to seek for alternative res-ervoirs for Helicobacter pylori. After isolation of Helicobacter pylori from dental plaque by culture method, researchers conducted trials to see whether the oral cavity could be a potential shelter for Helicobacter pylori. The following studies have detected Helicobacter pylori in the oral cavity. Interestingly, the Helicobacter pylori prevalence was higher in the oral cavity than in the stomach. Systemic antibiotics do not affect particularly Helicobacter pylori in dental plaque due to its biofilm structure. Therefore, it must be removed mechanically as in periodontal disease. As a matter of fact, clinical studies have shown that Helicobacter pylori infection treatment eradicates the bacteria in the stomach but does not affect the bacteria in the oral cavity. Moreover, clinical studies showed that periodontal treatment increases the success rate of gastric eradication therapy when used as an adjunct to the conventional triple eradication therapy. Based on these data, coordination of gastroenterologists with dentists may increase the success rate of gastric Helicobacter pylori eradication treatment. Therefore, the aim of this review is to discuss the existing evidence for the presence of Helicobacter pylori in the oral cavity and the contribution of periodontal treatment as an adjunct to gastric Helicobacter pylori eradication therapy.