Rare association between ankylosing spondylitis and paget's disease: A case of pagetic vertebral ankylosis


Cengiz C. B., Kızıltepe M., Kaplan H., Kökoğlu E., Denizhan T., Şenel A. S.

ARCHIVES OF OSTEOPOROSIS, vol.20, no.1, 2024 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2024
  • Doi Number: 10.1007/s11657-024-01490-4
  • Journal Name: ARCHIVES OF OSTEOPOROSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Keywords: Ankylosing spondylitis, Bone remodeling, Paget's disease, Pagetic vertebral ankylosis
  • Erciyes University Affiliated: Yes

Abstract

Paget's disease is a condition marked by abnormal bone remodeling, involving both excessive bone formation and destruction, predominantly in the elderly. Pagetic vertebral ankylosis is a rare manifestation, often associated with Paget's disease, ankylosing spondylitis, or diffuse idiopathic skeletal hyperostosis. This form of acquired vertebral ankylosis is uncommon and occurs in cases with bone-bridging syndesmophytes or osteophytes. Here, we present a case of delayed diagnosis of Paget's disease in the lower vertebral column, progressing to cervicothoracic vertebral ankylosis secondary to ankylosing spondylitis.