Cutaneous ulcerations caused by Paecilomyces variotii in a renal transplant recipient

EREN D., EROĞLU E., Kilic A., ATALAY M. A., MUMCU N., SİPAHİOĞLU M. H., ...Daha Fazla

TRANSPLANT INFECTIOUS DISEASE, cilt.20, sa.3, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/tid.12871
  • Dergi Adı: TRANSPLANT INFECTIOUS DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: fungal infection, immunosuppression, Paecilomyces variotii, transplantation, KIDNEY-TRANSPLANTATION, PATIENT, INFECTION, LILACINUS, HYALOHYPHOMYCOSIS, PNEUMONIA, DISEASE
  • Erciyes Üniversitesi Adresli: Evet

Özet

Skin infections caused by Paecilomyces species have been rarely described in patients with solid organ transplantation. Cutaneous manifestations are highly variable and include erythematous macules, nodules, pustules, and vesicular and necrotic lesions. The diagnosis of these infections is generally made by examination of a skin biopsy. Management of these fungal infections is difficult due to the immunocompromised state of the patients. Moreover, antifungal therapy and immunosuppressive drug interactions should be considered during treatment management. Herein, we reported a case of cellulitis caused by Paecilomyces variotii in a 56-year-old man who had undergone a kidney transplantation. Erythematous macular and nodular lesions on the left hand and left foot appeared first; within 2months the skin lesions became ulcerated, hemorrhagic, and progressively painful and the patient was admitted to our hospital. The diagnosis was made by skin biopsy and tissue culture. The skin lesions resolved by the sixth week of the treatment with voriconazole.