Bilirubin Levels and the Burden of Coronary Atherosclerosis in Patients With STEMI

Sahin O., Akpek M., Elcik D., Karadavut S., Simsek V., Tulmac M., ...Daha Fazla

ANGIOLOGY, cilt.64, sa.3, ss.200-204, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1177/0003319712440619
  • Dergi Adı: ANGIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.200-204
  • Anahtar Kelimeler: SYNTAX score, bilirubin, ST-elevated myocardial infarction, HEME OXYGENASE, ARTERY-DISEASE, SYNTAX SCORE, MYOCARDIAL-INFARCTION, CARBON-MONOXIDE, URIC-ACID, INTERVENTION, ASSOCIATION, ANTIOXIDANT, EXPRESSION
  • Erciyes Üniversitesi Adresli: Evet

Özet

We investigated whether serum bilirubin level (a marker of heme oxygenase activity) is a predictor of high levels of SYNTAX score (SXscore) in patients with acute myocardial infarction. Patients (n = 281; male 77%; mean age 60 +/- 12) who were admitted with ST-elevation myocardial infarctions (STEMIs) were enrolled. Patients were divided into 2 groups. Group 1 was defined as SXscore <22 and group 2 was defined as SXscore >= 22. Total bilirubin levels were significantly higher in the high-SXscore group than in the low-SXscore group (0.86 +/- 0.42 vs 1.02 +/- 0.51, P = .005). A significant correlation was detected between total bilirubin and SXscore (r = .42; P = .001). At multivariate analysis, total bilirubin (odds ratio: 1.86, 95% confidence interval 1.04-3.35; P = .038) was an independent risk factor for high SXscore in patients with STEMI. In conclusion, serum bilirubin level is independently associated with SXscore in patients with STEMI.