Increased DNA damage and increased apoptosis and necrosis in patients with severe sepsis and septic shock


Bahar I. , Elay G. , BAŞKOL G. , SUNGUR M. , Donmez-Altuntas H.

JOURNAL OF CRITICAL CARE, vol.43, pp.271-275, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43
  • Publication Date: 2018
  • Doi Number: 10.1016/j.jcrc.2017.09.035
  • Title of Journal : JOURNAL OF CRITICAL CARE
  • Page Numbers: pp.271-275
  • Keywords: Sepsis, Oxidative DNA damage, Micronucleus, CAMPAIGN INTERNATIONAL GUIDELINES, CELL-DEATH, MICRONUCLEUS, LYMPHOCYTES, MANAGEMENT

Abstract

Purpose: Reactive oxygen species (ROS) has a key role in the pathogenesis of sepsis. We wanted to evaluate ROS associated lymphocyte necrosis and apoptosis.