Increased DNA damage and increased apoptosis and necrosis in patients with severe sepsis and septic shock

Bahar, Ilhan; Elay, Gülseren; BAŞKOL, GÜLDEN; SUNGUR, MURAT; Donmez-Altuntas, HAMİYET

doi:10.1016/j.jcrc.2017.09.035

Increased DNA damage and increased apoptosis and necrosis in patients with severe sepsis and septic shock

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Bahar I., Elay G., BAŞKOL G., SUNGUR M., Donmez-Altuntas H.

JOURNAL OF CRITICAL CARE, vol.43, pp.271-275, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 43
Publication Date: 2018
Doi Number: 10.1016/j.jcrc.2017.09.035
Journal Name: JOURNAL OF CRITICAL CARE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.271-275
Keywords: Sepsis, Oxidative DNA damage, Micronucleus, CAMPAIGN INTERNATIONAL GUIDELINES, CELL-DEATH, MICRONUCLEUS, LYMPHOCYTES, MANAGEMENT
Erciyes University Affiliated: Yes

Abstract

Purpose: Reactive oxygen species (ROS) has a key role in the pathogenesis of sepsis. We wanted to evaluate ROS associated lymphocyte necrosis and apoptosis.