Increased DNA damage and increased apoptosis and necrosis in patients with severe sepsis and septic shock

Bahar, Ilhan; Elay, Gülseren; BAŞKOL, GÜLDEN; SUNGUR, MURAT; Donmez-Altuntas, HAMİYET

doi:10.1016/j.jcrc.2017.09.035

Increased DNA damage and increased apoptosis and necrosis in patients with severe sepsis and septic shock

Atıf İçin Kopyala

Bahar I., Elay G., BAŞKOL G., SUNGUR M., Donmez-Altuntas H.

JOURNAL OF CRITICAL CARE, cilt.43, ss.271-275, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 43
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.jcrc.2017.09.035
Dergi Adı: JOURNAL OF CRITICAL CARE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.271-275
Anahtar Kelimeler: Sepsis, Oxidative DNA damage, Micronucleus, CAMPAIGN INTERNATIONAL GUIDELINES, CELL-DEATH, MICRONUCLEUS, LYMPHOCYTES, MANAGEMENT
Erciyes Üniversitesi Adresli: Evet

Özet

Purpose: Reactive oxygen species (ROS) has a key role in the pathogenesis of sepsis. We wanted to evaluate ROS associated lymphocyte necrosis and apoptosis.