Neuroblastoma Arising From an Unresected Sacrococcygeal Teratoma in a Child


ÜNAL E., KÖKSAL Y., TOY H., GÜNEL E., AÇIKGÖZOGLU S.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.32, sa.3, ss.233-235, 2010 (SCI-Expanded) identifier identifier

Özet

Malignant transformation of a germ cell tumor, referring to the occurrence of somatic, nongerm cell malignancy within a germ cell tumor is a rare entity. The authors report a case of malignant transformation of an unreseceted sacrococcygeal teratoma to neuroblastoma in a 6-year-old girl and discuss this case in the light of relevant literature. This case shows that complete resection of germ cell tumor is necessary to prevent malignant transformation; In addition, when malignant transformation occurs, the treatment strategy must include surgery together with histology adapted systemic chemotherapy.