Neuroblastoma Arising From an Unresected Sacrococcygeal Teratoma in a Child

ÜNAL E., KÖKSAL Y., TOY H., GÜNEL E., AÇIKGÖZOGLU S.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.32, no.3, pp.233-235, 2010 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1097/mph.0b013e3181d4181c
  • Journal Name: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.233-235
  • Keywords: children, germ cell tumor, malignant transformation, neuroblastoma, sacrococcygeal mature cystic teratoma
  • Erciyes University Affiliated: Yes

Abstract

Malignant transformation of a germ cell tumor, referring to the occurrence of somatic, nongerm cell malignancy within a germ cell tumor is a rare entity. The authors report a case of malignant transformation of an unreseceted sacrococcygeal teratoma to neuroblastoma in a 6-year-old girl and discuss this case in the light of relevant literature. This case shows that complete resection of germ cell tumor is necessary to prevent malignant transformation; In addition, when malignant transformation occurs, the treatment strategy must include surgery together with histology adapted systemic chemotherapy.