Effect of kirenol on the interaction between the WNT/beta-Catenin and RUNX2/TCF/LEF1 pathways in fracture healing in vivo


KARAMAN İ. , Gunay A. B. , Yerer M. B. , DEMİRPOLAT E. , DOĞAN S. , Yay A. H. , ...Daha Fazla

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.54, ss.320-329, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 54 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/j.aott.2020.03.529
  • Dergi Adı: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Sayfa Sayıları: ss.320-329

Özet

Objective: This study aimed to determine the effects of a natural diterpenoid, kirenol, on fracture healing in vivo in an experimental rat model of femur fracture and investigate its potential mechanism of action via the Wnt/beta-catenin pathway.