Research Information System
DIAGNOSTICS, vol.15, no.741, pp.1-12, 2025 (SCI-Expanded)
Postoperative new-onset atrial fibrillation (AF)
(PNOAF) is the most common complication after coronary artery bypass graft (CABG),
and its incidence has been reported as up to 50% in studies. In this study, we investigated
whether there was a relationship between PNOAF and the neutrophil percentage
to albumin ratio (NPAR) levels after on-pump CABG. Methods: A total of 454 patients
who underwent CABG were included in the study. NPAR was calculated by dividing
the neutrophil count by the albumin value. Results: It was determined that 93 patients
developed PNOAF (20.4%). When the patient groups that developed and did not develop
PNOAF were compared in terms of laboratory findings, C-reactive protein (CRP)
values (4.0 mg/L (2.8–7.9) vs. 2.9 mg/L (1.1–6.7), <0.001), neutrophil/lymphocyte ratio
(NLR) (2.2 (1.2–4.2) vs. 1.4 (0.7–3.1), <0.001), platelets-to-lymphocyte ratio (112 (72–177) vs.
92 (69–122), <0.001) and NPAR (2.29 (1.68–3.8) vs. 1.09 (0.79–1.81), <0.001), were found
to be statistically significantly higher in the group that developed PNOAF. ROC analysis
showed that the cut-off value for NPAR for the development of PNOAF was 1.86 with 78%
sensitivity and 72% specificity (area under the ROC curve = 0.778, 95% CI (0.728–0.828),
p < 0.001). Conclusions: NPAR, which can be detected by a simple venous blood test, has
shown a strong predictive value for PNOAF in patients with CABG