Sepsis and Septic Shock; Current Treatment Dilemma and Role of Stem Cell Therapy in Pediatrics
ARCHIVES OF PEDIATRIC INFECTIOUS DISEASES, cilt.9, sa.3, 2021 (ESCI, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 9 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.5812/pedinfect.105301
- Dergi Adı: ARCHIVES OF PEDIATRIC INFECTIOUS DISEASES
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE
- Anahtar Kelimeler: Sepsis, Septic Shock, Mesenchymal Stem Cells, Animal Models, Cell- and Tissue-based Therapy, Treatment, Immunomodulation
- Erciyes Üniversitesi Adresli: Evet
Özet
Context: Sepsis's primary therapy consists of antibiotics therapy, supportive therapies, and source control of infection. The failure rate of this approach is about 20-40%. The widespread use of antibiotics has caused multiple drug resistance in primary etiological agents of sepsis in community-acquired and healthcare-associated infections. In the absence of new antibiotic options, alternative treatment modalities seem necessary.