Akademik Veri Yönetim Sistemi
Oncology: Genomics, Precision Medicine and Therapeutic Targets, Hardeep Singh Tuli,Mükerrem Betül Yerer Aycan, Editör, Springer, London/Berlin , London, ss.25-38, 2023
A common cause of all cancers leads us to a common definition. This definition is mutation. Cancer cells tend to constantly resist irregularity under the influence of the thermodynamic process in their microenvironment. At the end of this dynamic process, the changes that occur in the genome of the cell and the cumulative effect of these changes can cause the cell to be isolated from its cell community and act as an independent cell. Cancers describe a clonal increase in the number of cells that will cause a cell to lose control of itself against signals from its environment, allowing it to reproduce independently. One of the biggest reasons for this clonal increase is the genomic changes that occur in both protooncogenes and oncogenes.