The relationship between lymphocyte-to-monocyte ratio and saphenous vein graft patency in patients with coronary artery bypass graft


Oksuz F., Elcik D. , Yarlioglues M., Duran M., Ozturk S., Celik I. E. , ...More

BIOMARKERS IN MEDICINE, vol.11, no.10, pp.867-876, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 10
  • Publication Date: 2017
  • Doi Number: 10.2217/bmm-2017-0079
  • Title of Journal : BIOMARKERS IN MEDICINE
  • Page Numbers: pp.867-876
  • Keywords: atherosclerosis, coronary artery bypass graft, inflammation, lymphocyte-to-monocyte ratio, saphenous vein graft, BLOOD-CELL COUNT, ELEVATION MYOCARDIAL-INFARCTION, INTERNAL MAMMARY ARTERY, HEART-DISEASE, PREDICTIVE-VALUE, RISK-FACTOR, SURGERY, PATHOGENESIS, INFLAMMATION, GUIDELINES

Abstract

Aim: A lower lymphocyte count and a high monocyte count give important clues about the prognosis of various cardiovascular diseases. We hypothesized that lymphocyte-to-monocyte ratio (LMR) was associated with the saphenous vein graft disease (SVGD) in patients with coronary artery bypass graft (CABG). Patients & methods: A total of 218 patients with previous history of CABG surgery, who underwent coronary angiography due to stable angina symptoms, were investigated, retrospectively. Results: LMR levels were significantly lower in the SVGD group. Multiple logistic regression analyses showed that LMR levels were independent predictors of SVGD (OR: 0.648; 95% CI: 0.469-0.894; p = 0.008). Conclusion: Our results suggested that LMR levels may provide useful information for the relevant risk evaluation of SVGD in CABG patients.