The relationship between lymphocyte-to-monocyte ratio and saphenous vein graft patency in patients with coronary artery bypass graft

Oksuz F., Elcik D., Yarlioglues M., Duran M., Ozturk S., Celik I. E., ...More

BIOMARKERS IN MEDICINE, vol.11, no.10, pp.867-876, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 10
  • Publication Date: 2017
  • Doi Number: 10.2217/bmm-2017-0079
  • Journal Name: BIOMARKERS IN MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.867-876
  • Keywords: atherosclerosis, coronary artery bypass graft, inflammation, lymphocyte-to-monocyte ratio, saphenous vein graft, BLOOD-CELL COUNT, ELEVATION MYOCARDIAL-INFARCTION, INTERNAL MAMMARY ARTERY, HEART-DISEASE, PREDICTIVE-VALUE, RISK-FACTOR, SURGERY, PATHOGENESIS, INFLAMMATION, GUIDELINES
  • Erciyes University Affiliated: No

Abstract

Aim: A lower lymphocyte count and a high monocyte count give important clues about the prognosis of various cardiovascular diseases. We hypothesized that lymphocyte-to-monocyte ratio (LMR) was associated with the saphenous vein graft disease (SVGD) in patients with coronary artery bypass graft (CABG). Patients & methods: A total of 218 patients with previous history of CABG surgery, who underwent coronary angiography due to stable angina symptoms, were investigated, retrospectively. Results: LMR levels were significantly lower in the SVGD group. Multiple logistic regression analyses showed that LMR levels were independent predictors of SVGD (OR: 0.648; 95% CI: 0.469-0.894; p = 0.008). Conclusion: Our results suggested that LMR levels may provide useful information for the relevant risk evaluation of SVGD in CABG patients.