The miliyer tuberculosis mimirating oropharynx carcinoma in a patient using anti-TNF: Review of the literature

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KAHRAMAN DENİZHAN T., Kiziltepe M., Kaplan H., Kokoglu E. O., CENGİZ C. B., ŞENEL A. S.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, vol.16, pp.128-131, 2025 (ESCI) identifier

  • Publication Type: Article / Review
  • Volume: 16
  • Publication Date: 2025
  • Doi Number: 10.4328/acam.22312
  • Journal Name: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.128-131
  • Keywords: Anti-Tnf Treatment, Latent Tuberculosis, Miliary Tuberculosis
  • Erciyes University Affiliated: Yes

Abstract

Tumor necrosis factor-alpha (TNF-alpha) inhibitors are biological agents frequently used in many clinics, especially in rheumatology. In this article, we report a 59-year-old woman with RA who received adalimumab treatment for five years. The diagnosis and treatment of miliary tuberculosis secondary to irregular latent tuberculosis (TB) treatment with atypical symptoms will be discussed. In the literature, patients with a similar diagnosis who developed TB during treatment have also been presented. Patients at risk of latent TB who receive anti-TNF therapy should be closely monitored and the importance of prophylaxis should be emphasized.