Diğer, ss.1008, 2017
Aminoguanidine (AG) was presented more than 100 years ago. During the last 30 years
important effects of AG have been discovered which have made this molecule attract a lot of interest.
AG has anticancer effect on gastric cancer, and it has positive synergistic effect with
hemotherapeutic drugs. It may play important inhibitory roles in angiogenesis of gastric cancer. The
anticancer effect of iNOS inhibitors may include inducing cell apoptosis, suppressing cell
proliferation and reducing angiogenesis. Furthermore; we conducted a study on the formation,
catalytic activity and stability of hybrid nanoflowers (hNFs) containing AG and copper ions. The
synthesis of hNFs was accomplished using a modified method. The activities of hNFs were
determined by colorimetric and spectroscopic methods using guaiacol as a chromogenic substrate.
The hNFs were characterized using SEM, EDX, FT-IR analysis, UV-Vis spectrometry and XRD.