Transient monocular visual impairment as an initial symptom of COVID-19 infection in an individual with multiple sclerosis receiving teriflunomide

Yetkin M. F. , Yetkin N. A. , Akcakoyunlu M. , Mirza M.

NEUROLOGICAL SCIENCES, vol.42, no.5, pp.1661-1664, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 5
  • Publication Date: 2021
  • Doi Number: 10.1007/s10072-021-05097-2
  • Title of Journal : NEUROLOGICAL SCIENCES
  • Page Numbers: pp.1661-1664
  • Keywords: COVID-19, Multiple sclerosis, Teriflunomide


In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Since the outbreak of the pandemic, in addition to the well-known COVID-19 symptoms, various neurological symptoms have been also described in patients with COVID-19. Here, we report an unusual presentation of COVID-19 infection in a teriflunomide-treated individual with multiple sclerosis (MS) who did not interrupt teriflunomide treatment during the infection. The course of the infection was mild in this case as in other reported teriflunomide-treated individuals with COVID-19. COVID-19's presentation may be unusual in people with MS (pwMS). It can also be concluded that teriflunomide may be considered a safe disease-modifying treatment option during the pandemic.