SEROLOGY AND ANTHRAX IN HUMANS, LIVESTOCK AND ETOSHA-NATIONAL-PARK WILDLIFE

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TURNBULL P., DOGANAY M., LINDEQUE P., AYGEN B., MCLAUGHLIN J.

EPIDEMIOLOGY AND INFECTION, cilt.108, sa.2, ss.299-313, 1992 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 108 Sayı: 2
  • Basım Tarihi: 1992
  • Doi Numarası: 10.1017/s0950268800049773
  • Dergi Adı: EPIDEMIOLOGY AND INFECTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.299-313
  • Erciyes Üniversitesi Adresli: Evet

Özet

Results are presented from a number of epidemiological studies using enzyme immunoassays (EIA) based on the purified anthrax toxin antigens, protective antigen, lethal factor and oedema factor. Studies on sera from a group of 62 human anthrax patients in Turkey and from cattle in Britain following two unrelated outbreaks of anthrax show that EIA using protective antigen can be a useful diagnostic aid and will detect subclinical infections in appropriate circumstances. A serological survey on wildlife in the Etosha National Park, Namibia, where anthrax is endemic, showed that naturally acquired anthrax-specific antibodies are rare in herbivores but common in carnivores; in carnivores, titres appear to reflect the prevalence of anthrax in their ranges. Problems, as yet unresolved, were encountered in studies on sera from pigs following an outbreak of anthrax on a farm in Wales.