Crystal structure and Hirshfeld surface analysis of 1-[6-bromo-2-(3-bromophenyl)-1,2,3,4- tetrahydroquinolin-4-yl]pyrrolidin-2-one

Pronina, Anastasia; Kutasevich, Alexandra; Grigoriev, Mikhail; Hasanov, Khudayar; Sadikhova, Nurlana; Javadzade, Tahir; Akkurt, MEHMET; Bhattarai, Ajaya

doi:10.1107/s2056989024008144

Crystal structure and Hirshfeld surface analysis of 1-[6-bromo-2-(3-bromophenyl)-1,2,3,4- tetrahydroquinolin-4-yl]pyrrolidin-2-one

Pronina A. A., Kutasevich A. G., Grigoriev M. S., Hasanov K. I., Sadikhova N. D., Javadzade T. A., ...Daha Fazla

Acta Crystallographica Section E: Crystallographic Communications, cilt.80, sa.Pt 9, ss.967-972, 2024 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 80 Sayı: Pt 9
Basım Tarihi: 2024
Doi Numarası: 10.1107/s2056989024008144
Dergi Adı: Acta Crystallographica Section E: Crystallographic Communications
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.967-972
Anahtar Kelimeler: crystal structure, hydrogen bonds, the Povarov method, tetrahydroquinoline, Hirshfeld surface analysis
Erciyes Üniversitesi Adresli: Evet

Özet

This study presents the synthesis, characterization and Hirshfeld surface analysis of 1-[6-bromo-2-(3-bromophenyl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2- one, C19H18Br2N2O. In the title compound, the pyrrolidine ring adopts a distorted envelope configuration. In the crystal, molecules are linked by intermolecular N-H O, C-H O and C-H Br hydrogen bonds, forming a three-dimensional network. In addition, pairs of molecules along the c axis are connected by C-H π interactions. According to a Hirshfeld surface study, H H (36.9%), Br H/ Br (28.2%) and C H/H C (24.3%) interactions are the most significant contributors to the crystal packing.