Size-controlled clustering of iron oxide nanoparticles within fluorescent nanogels using LCST-driven self-assembly

Yildirim T., Pervez M., Li B., O'Reilly R. K.

JOURNAL OF MATERIALS CHEMISTRY B, cilt.8, sa.24, ss.5330-5335, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 24
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1039/c9tb02868d
  • Dergi Adı: JOURNAL OF MATERIALS CHEMISTRY B
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, Chimica, Communication Abstracts, Compendex, INSPEC, MEDLINE, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.5330-5335
  • Erciyes Üniversitesi Adresli: Hayır

Özet

Size-controlled clustering of iron oxide nanoparticles (IONPs) within the fluorescent polymer nanogels was achieved using the lower critical solution temperature (LCST) driven self-assembly and cross-linking of grafted polymer on the IONPs. The grafted polymer was comprised of oligoethyleneglycol methacrylate (OEGMA) and a novel dichloromaleimide functional methacrylate monomer as building blocks. As a result of the temperature responsive behavior of OEGMA, polymer grafted IONPs clustered to form larger nano-sized aggregates when heated above the LCST of the polymer. When these nano-sized aggregates were cross-linked using an amine-dichloromaleimide reaction, well-defined fluorescent hybrid nanogels could be fabricated. Moreover, the size of these hybrid nanogels was effectively controlled by varying the initial concentration of the polymer grafted IONPs in water.