The effects of topical estriol and vehicle cream on the mechanical and histological properties of normal rat skin

Ozyazgan I. , Liman N. , Eskitascioglu T.

MEDICAL SCIENCE MONITOR, vol.11, no.11, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 11
  • Publication Date: 2005
  • Title of Journal : MEDICAL SCIENCE MONITOR


Background: The biomechanical and histological effects of topical estriol in normal rat skin are not clearly defined, although several favourable effects of estrogens have been suggested, especially in the postmenopausal period. Our goal was to determine whether estrogens have any such effects on skin histology and biomechanical properties in an experimental rat model.