Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Induced by Cefazolin and Gentamicin in a Child


YILMAZ K., GÜNDÜZ Z., TAHAN F., AKAR H. H.

HONG KONG JOURNAL OF PAEDIATRICS, vol.21, no.2, pp.102-104, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 2
  • Publication Date: 2016
  • Journal Name: HONG KONG JOURNAL OF PAEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.102-104
  • Erciyes University Affiliated: Yes

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, is an uncommon, acute and severe life-threatening systemic disease. DRESS syndrome is characterised by fever, skin rash, lymph node enlargement, and internal organ involvement. The most common culprit drugs are anticonvulsants and allopurinol. We first reported a case of DRESS syndrome induced by cefazolin and gentamicin in a child. We aimed to emphasize the severity of renal damage and the dramatic response to short term intravenous and oral steroid therapy.