Ephedrine enhances the antinociceptive effect of dexmedetomidine in mice

SEZER Z., Sezer G., Tekol Y.

NEUROENDOCRINOLOGY LETTERS, cilt.32, sa.4, ss.552-556, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 4
  • Basım Tarihi: 2011
  • Dergi Adı: NEUROENDOCRINOLOGY LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.552-556
  • Erciyes Üniversitesi Adresli: Evet

Özet

OBJECTIVES: Dexmedetomidine, a highly selective alpha-2-adrenoceptor agonist, was recently introduced into clinical practice for its sedative and analgesic properties. The purpose of this study was to evaluate whether the psychostimulant drug ephedrine has any effect on dexmedetomidine-induced antinociception and locomotor inhibitor activity in mice in acute application.