Ephedrine enhances the antinociceptive effect of dexmedetomidine in mice


SEZER Z. , Sezer G., Tekol Y.

NEUROENDOCRINOLOGY LETTERS, cilt.32, ss.552-556, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 32 Konu: 4
  • Basım Tarihi: 2011
  • Dergi Adı: NEUROENDOCRINOLOGY LETTERS
  • Sayfa Sayıları: ss.552-556

Özet

OBJECTIVES: Dexmedetomidine, a highly selective alpha-2-adrenoceptor agonist, was recently introduced into clinical practice for its sedative and analgesic properties. The purpose of this study was to evaluate whether the psychostimulant drug ephedrine has any effect on dexmedetomidine-induced antinociception and locomotor inhibitor activity in mice in acute application.