Facile and convenient synthesis of 2,4-disubstituted and 2,3,4-trisubstituted 1,3-thiazoles

Hassan, Alaa; Mohamed, Shaaban; Mohamed, Nasr; El-Shaieb, Kamal; Abdel-Aziz, Ahmed; Mague, Joel; AKKURT, MEHMET

doi:10.1080/17415993.2015.1114621

Facile and convenient synthesis of 2,4-disubstituted and 2,3,4-trisubstituted 1,3-thiazoles

Hassan A. A., Mohamed S. K., Mohamed N. K., El-Shaieb K. M. A., Abdel-Aziz A. T., Mague J. T., ...Daha Fazla

JOURNAL OF SULFUR CHEMISTRY, cilt.37, sa.2, ss.162-175, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 37 Sayı: 2
Basım Tarihi: 2016
Doi Numarası: 10.1080/17415993.2015.1114621
Dergi Adı: JOURNAL OF SULFUR CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.162-175
Erciyes Üniversitesi Adresli: Evet

Özet

An efficient route for the synthesis of (E)-2-(2-(2-nitrobenzylidene)-hydrazinyl)-4-phenylthiazol-3-ium bromide, (E)-2-(2(substituted benzylidene)hydrazinyl)-4-phenylthiazoles and (E)-4-(4-bromophenyl)-2-(cycloalkylidenehydrazono)-3-phenyl-2,3-dihydrothiazoles by reaction of 1-aryl-2-bromoethanones with 2-(1-substituted methylidene)hydrazinecarbothioamides and cycloalkylidene-N-phenyl-hydrazinecarbothioamides. The structure of the products has been confirmed by using IR, NMR, mass spectrometry and single-crystal X-ray analyses.