Facile and convenient synthesis of 2,4-disubstituted and 2,3,4-trisubstituted 1,3-thiazoles


Hassan A. A. , Mohamed S. K. , Mohamed N. K. , El-Shaieb K. M. A. , Abdel-Aziz A. T. , Mague J. T. , ...Daha Fazla

JOURNAL OF SULFUR CHEMISTRY, cilt.37, ss.162-175, 2016 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 37 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1080/17415993.2015.1114621
  • Dergi Adı: JOURNAL OF SULFUR CHEMISTRY
  • Sayfa Sayıları: ss.162-175

Özet

An efficient route for the synthesis of (E)-2-(2-(2-nitrobenzylidene)-hydrazinyl)-4-phenylthiazol-3-ium bromide, (E)-2-(2(substituted benzylidene)hydrazinyl)-4-phenylthiazoles and (E)-4-(4-bromophenyl)-2-(cycloalkylidenehydrazono)-3-phenyl-2,3-dihydrothiazoles by reaction of 1-aryl-2-bromoethanones with 2-(1-substituted methylidene)hydrazinecarbothioamides and cycloalkylidene-N-phenyl-hydrazinecarbothioamides. The structure of the products has been confirmed by using IR, NMR, mass spectrometry and single-crystal X-ray analyses.