Acute and Chronic Effects of Electroconvulsive Therapy on Neuroactive Steroids in Patients with Major Depressive Disorder

Oezoyi S. , EŞEL E. , Hacimusalar Y. , CANDAN Z., Kula M. , Turan T.

TURK PSIKIYATRI DERGISI, vol.19, no.4, pp.341-348, 2008 (Journal Indexed in SSCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2008
  • Title of Journal : TURK PSIKIYATRI DERGISI
  • Page Numbers: pp.341-348


Objective: Baseline serum levels of neuroactive steroids such as dehydroepiandrosterone sulfate (DHEAS), 17-hydroxyprogesterone (17-OHP), testosterone, and cortisol were measured, and the acute and long-term effects of electroconvulsive therapy (ECT) on these hormones and the effect of gender on alterations in steroid hormones were investigated in patients with major depressive disorder (MDD).