Increased advanced oxidation protein products in Behcet's disease: a new activity marker?

Yazici C., Kose K., Calis M., Demir M., Kirnap M., Ates F.

BRITISH JOURNAL OF DERMATOLOGY, vol.151, no.1, pp.105-111, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 151 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1111/j.1365-2133.2004.06003.x
  • Journal Name: BRITISH JOURNAL OF DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.105-111
  • Keywords: advanced oxidation protein products, Behcet's disease, neutrophil-myeloperoxidase system, oxidative stress, protein oxidation, uveitis, SUPEROXIDE SCAVENGING ACTIVITY, CHRONIC-RENAL-FAILURE, MYELOPEROXIDASE LEVELS, LIPID-PEROXIDATION, HYPOCHLOROUS ACID, PLASMA, STRESS, INFLAMMATION, ANTIOXIDANTS, LEUKOCYTES
  • Erciyes University Affiliated: Yes

Abstract

Background Behcet's disease (BD) is a chronic inflammatory disease with unknown pathogenesis As various functions of neutrophils in peripheral blood, such as chemotaxis, phagocytosis and generation of reactive oxygen species (ROS) increase in BD, ROS-mediated oxidative stress related to neutrophil activation may have an important role in the pathogenesis of BD.