Interferon-gamma assays for the diagnosis of tuberculosis infection before using tumour necrosis factor-alpha blockers


Cobanoglu N., Ozcelik U., Kalyoncu U., Ozen S., Kiraz S., Gurcan N., ...More

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, vol.11, no.11, pp.1177-1182, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 11
  • Publication Date: 2007
  • Journal Name: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1177-1182
  • Erciyes University Affiliated: Yes

Abstract

OBJECTIVES: Patients who receive tumour necrosis factor-alpha (TNF-alpha) blockers are mostly immunosuppressed. A study was performed to investigate whether an interferon-gamma (IFN-gamma) assay could rep-resent an alternative approach to the tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection (LTBI) in these patients.