Botulinum Toxin-A to Improve Urethral Wound Healing: An Experimental Study in a Rat Model

Sahinkanat T., Ozkan K. U. , Ciralik H., Ozturk S., Resim S.

UROLOGY, vol.73, no.2, pp.405-409, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1016/j.urology.2008.07.051
  • Title of Journal : UROLOGY
  • Page Numbers: pp.405-409


OBJECTIVES Tensile distracting forces caused by elements such as a muscle pull can cause widening of scars in the tissue during the Wound healing process. The aim of the present Study was to investigate whether induced immobilization of the urethral muscle Using botulinum toxin-A (BTX-A) enhances wound healing and also reduces the amount of scar formation in an experimentally induced urethral injury in a male rat model.